nordihydroguaiaretic acid-203 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the nordihydroguaiaretic acid-203 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM2 adrenomedullin 2
AGFG1 ArfGAP with FG repeats 1
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
ARHGAP5 Rho GTPase activating protein 5
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C2CD2L C2CD2-like
CADM1 cell adhesion molecule 1
CCKAR cholecystokinin A receptor
CHD9 chromodomain helicase DNA binding protein 9
CLIC5 chloride intracellular channel 5
CST5 cystatin D
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DBT dihydrolipoamide branched chain transacylase E2
DCAF7 DDB1 and CUL4 associated factor 7
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DIEXF digestive organ expansion factor homolog (zebrafish)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DPEP1 dipeptidase 1 (renal)
DUSP22 dual specificity phosphatase 22
EFNB3 ephrin-B3
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ERN2 endoplasmic reticulum to nucleus signaling 2
F5 coagulation factor V (proaccelerin, labile factor)
FXR2 fragile X mental retardation, autosomal homolog 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GALR3 galanin receptor 3
GJA9 gap junction protein, alpha 9, 59kDa
GLG1 golgi glycoprotein 1
GSK3A glycogen synthase kinase 3 alpha
HCG26 HLA complex group 26 (non-protein coding)
HES1 hes family bHLH transcription factor 1
HHLA1 HERV-H LTR-associating 1
HIST1H3I histone cluster 1, H3i
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IGKC immunoglobulin kappa constant
IL15RA interleukin 15 receptor, alpha
IL18RAP interleukin 18 receptor accessory protein
IRF8 interferon regulatory factor 8
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LIF leukemia inhibitory factor
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP6 low density lipoprotein receptor-related protein 6
MALT1 MALT1 paracaspase
MAP2K5 mitogen-activated protein kinase kinase 5
MBNL2 muscleblind-like splicing regulator 2
MIA melanoma inhibitory activity
MKL1 megakaryoblastic leukemia (translocation) 1
MRPS30 mitochondrial ribosomal protein S30
MVK mevalonate kinase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO9B myosin IXB
MYOZ1 myozenin 1
NRGN neurogranin (protein kinase C substrate, RC3)
OGG1 8-oxoguanine DNA glycosylase
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEX11A peroxisomal biogenesis factor 11 alpha
PLA2G12A phospholipase A2, group XIIA
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRDX2 peroxiredoxin 2
PVALB parvalbumin
RANBP3 RAN binding protein 3
RBL2 retinoblastoma-like 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNDC3A RUN domain containing 3A
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRPA signal-regulatory protein alpha
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC38A7 solute carrier family 38, member 7
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SUSD4 sushi domain containing 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGM2 transglutaminase 2
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMPRSS6 transmembrane protease, serine 6
TRAK1 trafficking protein, kinesin binding 1
TRAPPC12 trafficking protein particle complex 12
TRIO trio Rho guanine nucleotide exchange factor
USP20 ubiquitin specific peptidase 20
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WBP4 WW domain binding protein 4
WNT16 wingless-type MMTV integration site family, member 16
WRAP53 WD repeat containing, antisense to TP53
ZNF142 zinc finger protein 142
ZNF331 zinc finger protein 331
ZNF668 zinc finger protein 668
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABLIM3 actin binding LIM protein family, member 3
ACBD4 acyl-CoA binding domain containing 4
ADCK3 aarF domain containing kinase 3
AHSP alpha hemoglobin stabilizing protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AMN amnion associated transmembrane protein
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARR3 arrestin 3, retinal (X-arrestin)
ASPA aspartoacylase
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AXIN1 axin 1
BBC3 BCL2 binding component 3
BCCIP BRCA2 and CDKN1A interacting protein
BEST2 bestrophin 2
C11ORF80 chromosome 11 open reading frame 80
C1ORF105 chromosome 1 open reading frame 105
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF30 chromosome 5 open reading frame 30
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CAV3 caveolin 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL19 chemokine (C-C motif) ligand 19
CCNO cyclin O
CD5 CD5 molecule
CD82 CD82 molecule
CD8A CD8a molecule
CIDEC cell death-inducing DFFA-like effector c
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN11 claudin 11
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPTP ceramide-1-phosphate transfer protein
CRMP1 collapsin response mediator protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1A DNA cross-link repair 1A
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DUSP13 dual specificity phosphatase 13
ENO3 enolase 3 (beta, muscle)
ERCC2 excision repair cross-complementation group 2
FAIM Fas apoptotic inhibitory molecule
FAM153A family with sequence similarity 153, member A
FOXC1 forkhead box C1
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GML glycosylphosphatidylinositol anchored molecule like
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GREB1L growth regulation by estrogen in breast cancer-like
GRIP2 glutamate receptor interacting protein 2
HLA-J major histocompatibility complex, class I, J (pseudogene)
INA internexin neuronal intermediate filament protein, alpha
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMO1 LIM domain only 1 (rhombotin 1)
LPAR3 lysophosphatidic acid receptor 3
MED17 mediator complex subunit 17
MOCS3 molybdenum cofactor synthesis 3
MUC6 mucin 6, oligomeric mucus/gel-forming
MXRA8 matrix-remodelling associated 8
NBAS neuroblastoma amplified sequence
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PDZD7 PDZ domain containing 7
PGC progastricsin (pepsinogen C)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD2L1 polycystic kidney disease 2-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRDM14 PR domain containing 14
PRDM5 PR domain containing 5
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC26A10 solute carrier family 26, member 10
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SND1-IT1 SND1 intronic transcript 1
SRPK3 SRSF protein kinase 3
SSTR4 somatostatin receptor 4
ST5 suppression of tumorigenicity 5
STOML1 stomatin (EPB72)-like 1
SYNPO synaptopodin
SYP synaptophysin
TEAD3 TEA domain family member 3
TLR5 toll-like receptor 5
TMEM176A transmembrane protein 176A
TMSB4Y thymosin beta 4, Y-linked
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAC T cell receptor alpha constant
TRIM45 tripartite motif containing 45
TSPAN32 tetraspanin 32
TSPYL2 TSPY-like 2
TTC13 tetratricopeptide repeat domain 13
TWF2 twinfilin actin binding protein 2
UBXN6 UBX domain protein 6
ZBED8 zinc finger, BED-type containing 8
ZNF322P1 zinc finger protein 322 pseudogene 1