nordihydroguaiaretic acid-2683 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nordihydroguaiaretic acid-2683 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADCK4 aarF domain containing kinase 4
AMDHD2 amidohydrolase domain containing 2
ARHGAP35 Rho GTPase activating protein 35
ASPH aspartate beta-hydroxylase
BRSK2 BR serine/threonine kinase 2
C17ORF59 chromosome 17 open reading frame 59
CARTPT CART prepropeptide
CD247 CD247 molecule
CD300C CD300c molecule
CDC42 cell division cycle 42
CDH10 cadherin 10, type 2 (T2-cadherin)
CDRT1 CMT1A duplicated region transcript 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFHR5 complement factor H-related 5
CNTNAP1 contactin associated protein 1
COL1A2 collagen, type I, alpha 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRAT carnitine O-acetyltransferase
CREB3L1 cAMP responsive element binding protein 3-like 1
CTSZ cathepsin Z
CXCL3 chemokine (C-X-C motif) ligand 3
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DMD dystrophin
DOPEY2 dopey family member 2
DPT dermatopontin
DUSP4 dual specificity phosphatase 4
ECEL1 endothelin converting enzyme-like 1
ETV7 ets variant 7
EYA4 EYA transcriptional coactivator and phosphatase 4
FER fer (fps/fes related) tyrosine kinase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPM6B glycoprotein M6B
GPR15 G protein-coupled receptor 15
GRIP2 glutamate receptor interacting protein 2
HOXA10 homeobox A10
HOXB3 homeobox B3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRH4 histamine receptor H4
ICOSLG inducible T-cell co-stimulator ligand
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGL immunoglobulin lambda locus
IL12B interleukin 12B
ITGA9 integrin, alpha 9
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCTD20 potassium channel tetramerization domain containing 20
KIF3C kinesin family member 3C
KLHL35 kelch-like family member 35
KRT86 keratin 86, type II
KRTAP2-4 keratin associated protein 2-4
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LRRC15 leucine rich repeat containing 15
MBNL2 muscleblind-like splicing regulator 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTMR8 myotubularin related protein 8
NF2 neurofibromin 2 (merlin)
NLRP1 NLR family, pyrin domain containing 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
OR2J2 olfactory receptor, family 2, subfamily J, member 2
ORC5 origin recognition complex, subunit 5
PCP4 Purkinje cell protein 4
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PHOX2A paired-like homeobox 2a
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PQBP1 polyglutamine binding protein 1
PRKCQ protein kinase C, theta
PRO2964 uncharacterized protein PRO2964
PTCRA pre T-cell antigen receptor alpha
PTEN phosphatase and tensin homolog
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBPMS RNA binding protein with multiple splicing
RGS12 regulator of G-protein signaling 12
RGS4 regulator of G-protein signaling 4
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SORBS3 sorbin and SH3 domain containing 3
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUGCT succinyl-CoA:glutarate-CoA transferase
TBX5 T-box 5
TLK1 tousled-like kinase 1
TMEM63A transmembrane protein 63A
TMPRSS4 transmembrane protease, serine 4
TUBB2B tubulin, beta 2B class IIb
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VAV2 vav 2 guanine nucleotide exchange factor
WNT8B wingless-type MMTV integration site family, member 8B
WSCD1 WSC domain containing 1
ZFPL1 zinc finger protein-like 1
ZNF385D zinc finger protein 385D

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGB androglobin
ADGRE3 adhesion G protein-coupled receptor E3
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANAPC2 anaphase promoting complex subunit 2
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOC4 apolipoprotein C-IV
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARL15 ADP-ribosylation factor-like 15
ATAD3A ATPase family, AAA domain containing 3A
ATAD5 ATPase family, AAA domain containing 5
BAHCC1 BAH domain and coiled-coil containing 1
BCAR3 breast cancer anti-estrogen resistance 3
BCORL1 BCL6 corepressor-like 1
C14ORF93 chromosome 14 open reading frame 93
C8A complement component 8, alpha polypeptide
C9ORF91 chromosome 9 open reading frame 91
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC92 coiled-coil domain containing 92
CCRL2 chemokine (C-C motif) receptor-like 2
CDK6 cyclin-dependent kinase 6
CGA glycoprotein hormones, alpha polypeptide
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLGN calmegin
CNN1 calponin 1, basic, smooth muscle
CPNE7 copine VII
DAAM1 dishevelled associated activator of morphogenesis 1
DEFB1 defensin, beta 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPEP2 dipeptidase 2
DUSP2 dual specificity phosphatase 2
ENO3 enolase 3 (beta, muscle)
FBXL2 F-box and leucine-rich repeat protein 2
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCHO1 FCH domain only 1
FLJ21369 uncharacterized protein FLJ21369
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GATA6 GATA binding protein 6
HCFC1 host cell factor C1
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HHLA3 HERV-H LTR-associating 3
HIST1H2AG histone cluster 1, H2ag
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IDI2-AS1 IDI2 antisense RNA 1
IL12RB1 interleukin 12 receptor, beta 1
IL18 interleukin 18
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0556 KIAA0556
KLF3 Kruppel-like factor 3 (basic)
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
KPTN kaptin (actin binding protein)
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MARC1 mitochondrial amidoxime reducing component 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MOCS3 molybdenum cofactor synthesis 3
MTMR11 myotubularin related protein 11
MXD3 MAX dimerization protein 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSD1 nuclear receptor binding SET domain protein 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDE12 phosphodiesterase 12
PMP22 peripheral myelin protein 22
POU5F1B POU class 5 homeobox 1B
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRDM12 PR domain containing 12
PRF1 perforin 1 (pore forming protein)
PRICKLE3 prickle homolog 3 (Drosophila)
PRR7 proline rich 7 (synaptic)
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
SETD1A SET domain containing 1A
SIDT1 SID1 transmembrane family, member 1
SIX3 SIX homeobox 3
SLC16A4 solute carrier family 16, member 4
SLC22A14 solute carrier family 22, member 14
SLITRK5 SLIT and NTRK-like family, member 5
SLPI secretory leukocyte peptidase inhibitor
SPATA2L spermatogenesis associated 2-like
STX17 syntaxin 17
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUFT1 tuftelin 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF671 zinc finger protein 671
ZNF696 zinc finger protein 696