nordihydroguaiaretic acid-415 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nordihydroguaiaretic acid-415 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ABHD17B abhydrolase domain containing 17B
AK1 adenylate kinase 1
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
AREG amphiregulin
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATP13A3 ATPase type 13A3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASR calcium-sensing receptor
CAV3 caveolin 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHKB choline kinase beta
CPD carboxypeptidase D
CREB1 cAMP responsive element binding protein 1
CUEDC1 CUE domain containing 1
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIO2 deiodinase, iodothyronine, type II
EEA1 early endosome antigen 1
ELF2 E74-like factor 2 (ets domain transcription factor)
EML4 echinoderm microtubule associated protein like 4
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
FAM76A family with sequence similarity 76, member A
FH fumarate hydratase
FNDC3A fibronectin type III domain containing 3A
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
GCKR glucokinase (hexokinase 4) regulator
GFOD2 glucose-fructose oxidoreductase domain containing 2
GPX2 glutathione peroxidase 2
H2AFV H2A histone family, member V
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2AI histone cluster 1, H2ai
HTATSF1 HIV-1 Tat specific factor 1
HUS1 HUS1 checkpoint homolog (S. pombe)
IGF1 insulin-like growth factor 1 (somatomedin C)
IL11 interleukin 11
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KDM4B lysine (K)-specific demethylase 4B
KDR kinase insert domain receptor
KIAA1109 KIAA1109
KRT6B keratin 6B, type II
LMTK2 lemur tyrosine kinase 2
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MGA MGA, MAX dimerization protein
MOGAT2 monoacylglycerol O-acyltransferase 2
MTMR3 myotubularin related protein 3
MTUS1 microtubule associated tumor suppressor 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG2 NDRG family member 2
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOTCH3 notch 3
NXT2 nuclear transport factor 2-like export factor 2
OCA2 oculocutaneous albinism II
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PCSK7 proprotein convertase subtilisin/kexin type 7
PDLIM5 PDZ and LIM domain 5
PGR progesterone receptor
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PSME4 proteasome (prosome, macropain) activator subunit 4
PTBP3 polypyrimidine tract binding protein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
RBL2 retinoblastoma-like 2
RET ret proto-oncogene
SCAMP1 secretory carrier membrane protein 1
SEC23IP SEC23 interacting protein
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SH2D1A SH2 domain containing 1A
SH3GL3 SH3-domain GRB2-like 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPON2 spondin 2, extracellular matrix protein
SQSTM1 sequestosome 1
STK4 serine/threonine kinase 4
STRN striatin, calmodulin binding protein
SUGP2 SURP and G patch domain containing 2
TBL1X transducin (beta)-like 1X-linked
TMEM206 transmembrane protein 206
TMF1 TATA element modulatory factor 1
TMOD3 tropomodulin 3 (ubiquitous)
TMX1 thioredoxin-related transmembrane protein 1
UBE2W ubiquitin-conjugating enzyme E2W (putative)
UBOX5 U-box domain containing 5
USO1 USO1 vesicle transport factor
VARS valyl-tRNA synthetase
WDR13 WD repeat domain 13
ZFR zinc finger RNA binding protein
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACVR2B activin A receptor, type IIB
ADM2 adrenomedullin 2
ADRA2C adrenoceptor alpha 2C
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARSA arylsulfatase A
ASCL3 achaete-scute family bHLH transcription factor 3
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAGE B melanoma antigen
BIK BCL2-interacting killer (apoptosis-inducing)
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C22ORF29 chromosome 22 open reading frame 29
C4BPA complement component 4 binding protein, alpha
CA14 carbonic anhydrase XIV
CBX8 chromobox homolog 8
CCDC94 coiled-coil domain containing 94
CCL17 chemokine (C-C motif) ligand 17
CD68 CD68 molecule
CDK5 cyclin-dependent kinase 5
CLIP3 CAP-GLY domain containing linker protein 3
CLPS colipase, pancreatic
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORO2A coronin, actin binding protein, 2A
CROT carnitine O-octanoyltransferase
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DGAT1 diacylglycerol O-acyltransferase 1
DYSF dysferlin
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EFNA1 ephrin-A1
EVPL envoplakin
FAM110D family with sequence similarity 110, member D
FANCE Fanconi anemia, complementation group E
FLRT1 fibronectin leucine rich transmembrane protein 1
FMO2 flavin containing monooxygenase 2 (non-functional)
GAB2 GRB2-associated binding protein 2
GALR3 galanin receptor 3
GNRH2 gonadotropin-releasing hormone 2
GREB1L growth regulation by estrogen in breast cancer-like
GRIP2 glutamate receptor interacting protein 2
H2AFY2 H2A histone family, member Y2
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP6 insulin-like growth factor binding protein 6
IL36RN interleukin 36 receptor antagonist
IL7R interleukin 7 receptor
ILK integrin-linked kinase
ITPKB inositol-trisphosphate 3-kinase B
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF15 Kruppel-like factor 15
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIAS lipoic acid synthetase
LOC390998 ribosomal protein L10 pseudogene
LOC440895 two pore channel 3 pseudogene
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
LY6G6C lymphocyte antigen 6 complex, locus G6C
MOB3B MOB kinase activator 3B
MTERF4 mitochondrial transcription termination factor 4
MTG1 mitochondrial ribosome-associated GTPase 1
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NRGN neurogranin (protein kinase C substrate, RC3)
OGFRL1 opioid growth factor receptor-like 1
OMG oligodendrocyte myelin glycoprotein
PAIP2B poly(A) binding protein interacting protein 2B
PCDH12 protocadherin 12
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
PSAT1 phosphoserine aminotransferase 1
PSCA prostate stem cell antigen
PTK6 protein tyrosine kinase 6
RHOH ras homolog family member H
RNF43 ring finger protein 43
RORC RAR-related orphan receptor C
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SCARA3 scavenger receptor class A, member 3
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIDT1 SID1 transmembrane family, member 1
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPAG11A sperm associated antigen 11A
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUSD4 sushi domain containing 4
SYT13 synaptotagmin XIII
TM7SF3 transmembrane 7 superfamily member 3
TSPAN15 tetraspanin 15
USP20 ubiquitin specific peptidase 20
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZC4H2 zinc finger, C4H2 domain containing