nordihydroguaiaretic acid-5220 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nordihydroguaiaretic acid-5220 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADAM22 ADAM metallopeptidase domain 22
AKR1C1 aldo-keto reductase family 1, member C1
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARID4B AT rich interactive domain 4B (RBP1-like)
ARMC4 armadillo repeat containing 4
ARNT aryl hydrocarbon receptor nuclear translocator
ART1 ADP-ribosyltransferase 1
BST2 bone marrow stromal cell antigen 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD101 CD101 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DICER1 dicer 1, ribonuclease type III
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSTYK dual serine/threonine and tyrosine protein kinase
EGF epidermal growth factor
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EPHB2 EPH receptor B2
EXPH5 exophilin 5
FAM188A family with sequence similarity 188, member A
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
GAL3ST4 galactose-3-O-sulfotransferase 4
GAP43 growth associated protein 43
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR143 G protein-coupled receptor 143
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HOXB5 homeobox B5
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
IFI35 interferon-induced protein 35
IL17RA interleukin 17 receptor A
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRF4 interferon regulatory factor 4
JUND jun D proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LAMP1 lysosomal-associated membrane protein 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEB2 melanoma antigen family B2
MAOA monoamine oxidase A
MAP2 microtubule-associated protein 2
MTA1 metastasis associated 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH14 myosin, heavy chain 14, non-muscle
NDRG1 N-myc downstream regulated 1
NEUROG2 neurogenin 2
NF1 neurofibromin 1
NOP16 NOP16 nucleolar protein
NRIP3 nuclear receptor interacting protein 3
PCDHA5 protocadherin alpha 5
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCSK6 proprotein convertase subtilisin/kexin type 6
PLAU plasminogen activator, urokinase
PQBP1 polyglutamine binding protein 1
PRDX2 peroxiredoxin 2
PTHLH parathyroid hormone-like hormone
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPL18 ribosomal protein L18
S100A13 S100 calcium binding protein A13
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOS2 son of sevenless homolog 2 (Drosophila)
SRCAP Snf2-related CREBBP activator protein
SRPK2 SRSF protein kinase 2
SRSF7 serine/arginine-rich splicing factor 7
STAB1 stabilin 1
STIM1 stromal interaction molecule 1
STK17A serine/threonine kinase 17a
SUGP1 SURP and G patch domain containing 1
TCEAL2 transcription elongation factor A (SII)-like 2
TMCC2 transmembrane and coiled-coil domain family 2
TOP3A topoisomerase (DNA) III alpha
TPMT thiopurine S-methyltransferase
TRIM10 tripartite motif containing 10
ULK2 unc-51 like autophagy activating kinase 2
VCAN versican
VIPR1 vasoactive intestinal peptide receptor 1
WSB1 WD repeat and SOCS box containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB7A zinc finger and BTB domain containing 7A
ZNF10 zinc finger protein 10
ZNF440 zinc finger protein 440
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACYP1 acylphosphatase 1, erythrocyte (common) type
ACYP2 acylphosphatase 2, muscle type
ANKRD36 ankyrin repeat domain 36
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
CAMTA2 calmodulin binding transcription activator 2
CBX4 chromobox homolog 4
CCNO cyclin O
CDT1 chromatin licensing and DNA replication factor 1
CENPO centromere protein O
CEP72 centrosomal protein 72kDa
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CLDN15 claudin 15
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCP1A decapping mRNA 1A
DDIT3 DNA-damage-inducible transcript 3
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNM1 dynamin 1
EAF2 ELL associated factor 2
ETAA1 Ewing tumor-associated antigen 1
FAM186A family with sequence similarity 186, member A
FAM50B family with sequence similarity 50, member B
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXL2 F-box and leucine-rich repeat protein 2
FURIN furin (paired basic amino acid cleaving enzyme)
GEMIN8 gem (nuclear organelle) associated protein 8
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GPATCH3 G patch domain containing 3
GPR1 G protein-coupled receptor 1
HIST1H4C histone cluster 1, H4c
HOXA4 homeobox A4
IL22 interleukin 22
KDM5C lysine (K)-specific demethylase 5C
KIF20B kinesin family member 20B
KIFC1 kinesin family member C1
KLHL28 kelch-like family member 28
KPTN kaptin (actin binding protein)
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LRP5L low density lipoprotein receptor-related protein 5-like
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MBTD1 mbt domain containing 1
METRN meteorin, glial cell differentiation regulator
MKNK2 MAP kinase interacting serine/threonine kinase 2
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXD3 MAX dimerization protein 3
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NLK nemo-like kinase
NOL12 nucleolar protein 12
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMCH pro-melanin-concentrating hormone
PMM1 phosphomannomutase 1
PNPLA6 patatin-like phospholipase domain containing 6
PRKX protein kinase, X-linked
PTCD2 pentatricopeptide repeat domain 2
PTK6 protein tyrosine kinase 6
QPCT glutaminyl-peptide cyclotransferase
QPCTL glutaminyl-peptide cyclotransferase-like
RFTN1 raftlin, lipid raft linker 1
RIBC2 RIB43A domain with coiled-coils 2
RNF2 ring finger protein 2
SH2D4A SH2 domain containing 4A
SIK1 salt-inducible kinase 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOWAHC sosondowah ankyrin repeat domain family member C
STARD5 StAR-related lipid transfer (START) domain containing 5
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN1 tectonic family member 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM180 transmembrane protein 180
TMEM212 transmembrane protein 212
TRAF2 TNF receptor-associated factor 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
UBXN6 UBX domain protein 6
WDR25 WD repeat domain 25
YIPF3 Yip1 domain family, member 3
ZBED1 zinc finger, BED-type containing 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF446 zinc finger protein 446
ZNF787 zinc finger protein 787