nordihydroguaiaretic acid-524 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the nordihydroguaiaretic acid-524 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAM22 ADAM metallopeptidase domain 22
AKIP1 A kinase (PRKA) interacting protein 1
APAF1 apoptotic peptidase activating factor 1
ARHGAP33 Rho GTPase activating protein 33
ARRB2 arrestin, beta 2
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
C19ORF66 chromosome 19 open reading frame 66
CCPG1 cell cycle progression 1
CCSER2 coiled-coil serine-rich protein 2
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CFAP70 cilia and flagella associated protein 70
CNGA1 cyclic nucleotide gated channel alpha 1
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24
DTX3 deltex 3, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
EHD1 EH-domain containing 1
FAM189A1 family with sequence similarity 189, member A1
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
FBXO31 F-box protein 31
FGD6 FYVE, RhoGEF and PH domain containing 6
FOXA2 forkhead box A2
FUZ fuzzy planar cell polarity protein
G3BP2 GTPase activating protein (SH3 domain) binding protein 2
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLRA2 glycine receptor, alpha 2
GPR137 G protein-coupled receptor 137
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
GSTT1 glutathione S-transferase theta 1
HIST1H2BF histone cluster 1, H2bf
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
KHSRP KH-type splicing regulatory protein
KIFAP3 kinesin-associated protein 3
KLF9 Kruppel-like factor 9
KRT7 keratin 7, type II
L1CAM L1 cell adhesion molecule
LUZP1 leucine zipper protein 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MINK1 misshapen-like kinase 1
MIS18A MIS18 kinetochore protein A
MRPL35 mitochondrial ribosomal protein L35
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MVK mevalonate kinase
NPFFR1 neuropeptide FF receptor 1
NPHP4 nephronophthisis 4
NR4A1 nuclear receptor subfamily 4, group A, member 1
NXPH3 neurexophilin 3
PAK1IP1 PAK1 interacting protein 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PODXL podocalyxin-like
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM14 PR domain containing 14
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTK2B protein tyrosine kinase 2 beta
RARA retinoic acid receptor, alpha
RBX1 ring-box 1, E3 ubiquitin protein ligase
RIMS2 regulating synaptic membrane exocytosis 2
RUNDC3A RUN domain containing 3A
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC2 syndecan 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC38A3 solute carrier family 38, member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX21 SRY (sex determining region Y)-box 21
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNGR1 synaptogyrin 1
TBX10 T-box 10
TEX13B testis expressed 13B
TG thyroglobulin
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM140 transmembrane protein 140
TMEM53 transmembrane protein 53
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNK2 tyrosine kinase, non-receptor, 2
TNN tenascin N
TOP3B topoisomerase (DNA) III beta
TOR1AIP1 torsin A interacting protein 1
TP53I11 tumor protein p53 inducible protein 11
TSPAN32 tetraspanin 32
TUB tubby bipartite transcription factor
VARS valyl-tRNA synthetase
WSB1 WD repeat and SOCS box containing 1
WTAP Wilms tumor 1 associated protein
ZC3H13 zinc finger CCCH-type containing 13

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRE5 adhesion G protein-coupled receptor E5
AGRP agouti related neuropeptide
AIDA axin interactor, dorsalization associated
ALAS1 5'-aminolevulinate synthase 1
ARHGAP5 Rho GTPase activating protein 5
ASTE1 asteroid homolog 1 (Drosophila)
ATF3 activating transcription factor 3
ATXN8OS ATXN8 opposite strand (non-protein coding)
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BNC2 basonuclin 2
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
C1D C1D nuclear receptor corepressor
CADPS2 Ca++-dependent secretion activator 2
CCDC130 coiled-coil domain containing 130
CCDC176 coiled-coil domain containing 176
CCDC85C coiled-coil domain containing 85C
CD48 CD48 molecule
CDC73 cell division cycle 73
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CETN1 centrin, EF-hand protein, 1
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CLDN15 claudin 15
CPB1 carboxypeptidase B1 (tissue)
CPOX coproporphyrinogen oxidase
CRYBG3 beta-gamma crystallin domain containing 3
CTSF cathepsin F
DCAF16 DDB1 and CUL4 associated factor 16
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC4 excision repair cross-complementation group 4
EXTL2 exostosin-like glycosyltransferase 2
FAM172A family with sequence similarity 172, member A
FAM188A family with sequence similarity 188, member A
FAR2 fatty acyl CoA reductase 2
FGR FGR proto-oncogene, Src family tyrosine kinase
GAB2 GRB2-associated binding protein 2
GLB1L galactosidase, beta 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL22 interleukin 22
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KRT38 keratin 38, type I
LEMD3 LEM domain containing 3
MAGT1 magnesium transporter 1
MALL mal, T-cell differentiation protein-like
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MARC1 mitochondrial amidoxime reducing component 1
METAP1 methionyl aminopeptidase 1
MEX3C mex-3 RNA binding family member C
MOCOS molybdenum cofactor sulfurase
MRPL44 mitochondrial ribosomal protein L44
MYL12B myosin, light chain 12B, regulatory
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NRGN neurogranin (protein kinase C substrate, RC3)
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PARM1 prostate androgen-regulated mucin-like protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PFAS phosphoribosylformylglycinamidine synthase
PLCD1 phospholipase C, delta 1
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RAB33B RAB33B, member RAS oncogene family
RBM47 RNA binding motif protein 47
RNF39 ring finger protein 39
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
SAC3D1 SAC3 domain containing 1
SALL2 spalt-like transcription factor 2
SETD4 SET domain containing 4
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC35E3 solute carrier family 35, member E3
SPEF1 sperm flagellar 1
STAT4 signal transducer and activator of transcription 4
TBX21 T-box 21
TMEM121 transmembrane protein 121
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRAPPC12 trafficking protein particle complex 12
TSHB thyroid stimulating hormone, beta
TSPAN15 tetraspanin 15
UBXN2B UBX domain protein 2B
USP20 ubiquitin specific peptidase 20
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR18 WD repeat domain 18
WDR44 WD repeat domain 44
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB10 zinc finger and BTB domain containing 10