nordihydroguaiaretic acid-5583 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the nordihydroguaiaretic acid-5583 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACVR1B activin A receptor, type IB
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADRA1B adrenoceptor alpha 1B
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AMPD3 adenosine monophosphate deaminase 3
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APC adenomatous polyposis coli
ATP10B ATPase, class V, type 10B
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATXN7L1 ataxin 7-like 1
BMP2 bone morphogenetic protein 2
C21ORF2 chromosome 21 open reading frame 2
C2ORF27A chromosome 2 open reading frame 27A
C8A complement component 8, alpha polypeptide
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN15 calpain 15
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDC14A cell division cycle 14A
CFAP70 cilia and flagella associated protein 70
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CSF1R colony stimulating factor 1 receptor
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGCR8 DGCR8 microprocessor complex subunit
DMXL2 Dmx-like 2
DNM3 dynamin 3
DPF1 D4, zinc and double PHD fingers family 1
DSCC1 DNA replication and sister chromatid cohesion 1
EFNB3 ephrin-B3
EN1 engrailed homeobox 1
FGF18 fibroblast growth factor 18
FPR1 formyl peptide receptor 1
FSCN1 fascin actin-bundling protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSK3A glycogen synthase kinase 3 alpha
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H4C histone cluster 1, H4c
HOXA1 homeobox A1
HOXB7 homeobox B7
IFI6 interferon, alpha-inducible protein 6
IL22 interleukin 22
ING4 inhibitor of growth family, member 4
ISG20 interferon stimulated exonuclease gene 20kDa
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
KLHL25 kelch-like family member 25
KRT19P2 keratin 19 pseudogene 2
LRP12 low density lipoprotein receptor-related protein 12
MIER2 mesoderm induction early response 1, family member 2
MYO7A myosin VIIA
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NNAT neuronatin
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCDH17 protocadherin 17
PDE4DIP phosphodiesterase 4D interacting protein
PDIA2 protein disulfide isomerase family A, member 2
PHF3 PHD finger protein 3
PKNOX1 PBX/knotted 1 homeobox 1
PLCE1 phospholipase C, epsilon 1
PON3 paraoxonase 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRLR prolactin receptor
PVR poliovirus receptor
RAB3B RAB3B, member RAS oncogene family
RHOQ ras homolog family member Q
RIMS2 regulating synaptic membrane exocytosis 2
RNF24 ring finger protein 24
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SIRT5 sirtuin 5
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SOCS3 suppressor of cytokine signaling 3
SSX3 synovial sarcoma, X breakpoint 3
STS steroid sulfatase (microsomal), isozyme S
TAZ tafazzin
TLR2 toll-like receptor 2
TM4SF4 transmembrane 4 L six family member 4
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM2 tripartite motif containing 2
TSPAN1 tetraspanin 1
TYRP1 tyrosinase-related protein 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
YY2 YY2 transcription factor
ZNF134 zinc finger protein 134
ZNF3 zinc finger protein 3
ZNF358 zinc finger protein 358
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAP2 ArfGAP with dual PH domains 2
ADGRE5 adhesion G protein-coupled receptor E5
AGO1 argonaute RISC catalytic component 1
ATP10D ATPase, class V, type 10D
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF105 chromosome 1 open reading frame 105
C2ORF54 chromosome 2 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CIC capicua transcriptional repressor
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK5 docking protein 5
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
FAM189A2 family with sequence similarity 189, member A2
FAM53B family with sequence similarity 53, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF23 fibroblast growth factor 23
FHIT fragile histidine triad
FLCN folliculin
GAMT guanidinoacetate N-methyltransferase
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GRB7 growth factor receptor-bound protein 7
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AJ histone cluster 1, H2aj
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL2 interleukin 2
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNIP1 Kv channel interacting protein 1
KDM8 lysine (K)-specific demethylase 8
KIAA0894 KIAA0894 protein
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT15 keratin 15, type I
LAMP3 lysosomal-associated membrane protein 3
LIME1 Lck interacting transmembrane adaptor 1
LOC100286895 cell division cycle 27 homolog pseudogene
LOC390998 ribosomal protein L10 pseudogene
LOXL3 lysyl oxidase-like 3
LPPR1 lipid phosphate phosphatase-related protein type 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP5L low density lipoprotein receptor-related protein 5-like
LY6G6C lymphocyte antigen 6 complex, locus G6C
MUC3A mucin 3A, cell surface associated
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ONECUT2 one cut homeobox 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PODXL2 podocalyxin-like 2
POM121 POM121 transmembrane nucleoporin
PROL1 proline rich, lacrimal 1
PRSS53 protease, serine, 53
RASAL1 RAS protein activator like 1 (GAP1 like)
RFPL3 ret finger protein-like 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SAMD9 sterile alpha motif domain containing 9
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A8 solute carrier family 12, member 8
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SOX3 SRY (sex determining region Y)-box 3
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TMEM62 transmembrane protein 62
TNS2 tensin 2
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UPK2 uroplakin 2
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
ZFHX2 zinc finger homeobox 2
ZNF250 zinc finger protein 250
ZNF282 zinc finger protein 282
ZNF304 zinc finger protein 304
ZNF442 zinc finger protein 442
ZNF606 zinc finger protein 606
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