nordihydroguaiaretic acid-6182 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the nordihydroguaiaretic acid-6182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADGRL1 adhesion G protein-coupled receptor L1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP13 A kinase (PRKA) anchor protein 13
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOC4 apolipoprotein C-IV
AQP7 aquaporin 7
ARG1 arginase 1
ASIC3 acid sensing (proton gated) ion channel 3
BICD1 bicaudal D homolog 1 (Drosophila)
C5ORF45 chromosome 5 open reading frame 45
CA5B carbonic anhydrase VB, mitochondrial
CABP2 calcium binding protein 2
CCDC134 coiled-coil domain containing 134
CCL27 chemokine (C-C motif) ligand 27
CDC25C cell division cycle 25C
CDRT1 CMT1A duplicated region transcript 1
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
DCAF17 DDB1 and CUL4 associated factor 17
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIAPH2 diaphanous-related formin 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
EED embryonic ectoderm development
FGFR1 fibroblast growth factor receptor 1
FOLR3 folate receptor 3 (gamma)
FRMPD1 FERM and PDZ domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G0S2 G0/G1 switch 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAREM GRB2 associated, regulator of MAPK1
GAS8 growth arrest-specific 8
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GPX2 glutathione peroxidase 2
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
GSK3A glycogen synthase kinase 3 alpha
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AK histone cluster 1, H2ak
HOXA10 homeobox A10
ICAM5 intercellular adhesion molecule 5, telencephalin
IL1RL1 interleukin 1 receptor-like 1
INHBA inhibin, beta A
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9
KIF1C kinesin family member 1C
KLHL25 kelch-like family member 25
LMF1 lipase maturation factor 1
LMTK2 lemur tyrosine kinase 2
MBNL2 muscleblind-like splicing regulator 2
MED25 mediator complex subunit 25
MET MET proto-oncogene, receptor tyrosine kinase
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MRC2 mannose receptor, C type 2
MSH3 mutS homolog 3
MST1L macrophage stimulating 1-like
NAV2 neuron navigator 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NMT2 N-myristoyltransferase 2
NOD2 nucleotide-binding oligomerization domain containing 2
NRSN2 neurensin 2
OPRL1 opiate receptor-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARVA parvin, alpha
PCDHGA3 protocadherin gamma subfamily A, 3
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PEX11A peroxisomal biogenesis factor 11 alpha
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PLD3 phospholipase D family, member 3
PLXNC1 plexin C1
PTCRA pre T-cell antigen receptor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PXDC1 PX domain containing 1
RAB3D RAB3D, member RAS oncogene family
RBBP4 retinoblastoma binding protein 4
RPL7 ribosomal protein L7
RRBP1 ribosome binding protein 1
SAMD4B sterile alpha motif domain containing 4B
SH3BGR SH3 domain binding glutamate-rich protein
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLCO1C1 solute carrier organic anion transporter family, member 1C1
SOCS7 suppressor of cytokine signaling 7
SORBS3 sorbin and SH3 domain containing 3
SPTBN1 spectrin, beta, non-erythrocytic 1
STAP1 signal transducing adaptor family member 1
STX2 syntaxin 2
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPSAB1 tryptase alpha/beta 1
TRAPPC9 trafficking protein particle complex 9
TRGV5 T cell receptor gamma variable 5
TRIM23 tripartite motif containing 23
TRIM3 tripartite motif containing 3
UNC5C unc-5 homolog C (C. elegans)
VPS13B vacuolar protein sorting 13 homolog B (yeast)
ZNF132 zinc finger protein 132
ZNF155 zinc finger protein 155

decreased expression

Symbol Name
AICDA activation-induced cytidine deaminase
ARSB arylsulfatase B
BCAS3 breast carcinoma amplified sequence 3
BTBD18 BTB (POZ) domain containing 18
C1ORF105 chromosome 1 open reading frame 105
CCDC121 coiled-coil domain containing 121
CCDC71 coiled-coil domain containing 71
CCL20 chemokine (C-C motif) ligand 20
CD1C CD1c molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHML choroideremia-like (Rab escort protein 2)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPTP ceramide-1-phosphate transfer protein
CRABP2 cellular retinoic acid binding protein 2
CTSV cathepsin V
DDN dendrin
DEAF1 DEAF1 transcription factor
DENND5B DENN/MADD domain containing 5B
DEPDC5 DEP domain containing 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOSC1 exosome component 1
FAM86B1 family with sequence similarity 86, member B1
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJA9 gap junction protein, alpha 9, 59kDa
GPR22 G protein-coupled receptor 22
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRPR gastrin-releasing peptide receptor
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC11 histone deacetylase 11
HHLA3 HERV-H LTR-associating 3
HIST1H1T histone cluster 1, H1t
HIST1H3G histone cluster 1, H3g
HIST1H4A histone cluster 1, H4a
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IGFBP4 insulin-like growth factor binding protein 4
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INO80D INO80 complex subunit D
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0753 KIAA0753
LAMB3 laminin, beta 3
LGALS4 lectin, galactoside-binding, soluble, 4
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC15 leucine rich repeat containing 15
LTB lymphotoxin beta (TNF superfamily, member 3)
MOB3B MOB kinase activator 3B
MTMR12 myotubularin related protein 12
MVD mevalonate (diphospho) decarboxylase
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NPFFR1 neuropeptide FF receptor 1
NT5M 5',3'-nucleotidase, mitochondrial
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PDE12 phosphodiesterase 12
PFN2 profilin 2
PGP phosphoglycolate phosphatase
PHF14 PHD finger protein 14
PLAG1 pleiomorphic adenoma gene 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKCE protein kinase C, epsilon
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRY PTPN13-like, Y-linked
PTCD1 pentatricopeptide repeat domain 1
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB8B RAB8B, member RAS oncogene family
RANBP17 RAN binding protein 17
REPS2 RALBP1 associated Eps domain containing 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC17A2 solute carrier family 17, member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOX21 SRY (sex determining region Y)-box 21
TBC1D17 TBC1 domain family, member 17
TBKBP1 TBK1 binding protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX40 testis expressed 40
THBS4 thrombospondin 4
THEM6 thioesterase superfamily member 6
TPBG trophoblast glycoprotein
TSC22D4 TSC22 domain family, member 4
TTC4 tetratricopeptide repeat domain 4
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB2A tubulin, beta 2A class IIa
UBTD1 ubiquitin domain containing 1
USP18 ubiquitin specific peptidase 18
WDR25 WD repeat domain 25
ZBED1 zinc finger, BED-type containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF492 zinc finger protein 492
ZNF862 zinc finger protein 862