nordihydroguaiaretic acid-6983 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the nordihydroguaiaretic acid-6983 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACSF2 acyl-CoA synthetase family member 2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ANKMY1 ankyrin repeat and MYND domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARL4C ADP-ribosylation factor-like 4C
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG12 autophagy related 12
BAIAP3 BAI1-associated protein 3
BMP5 bone morphogenetic protein 5
CAPN9 calpain 9
CCNO cyclin O
CFLAR CASP8 and FADD-like apoptosis regulator
CIDEB cell death-inducing DFFA-like effector b
CLMN calmin (calponin-like, transmembrane)
CORT cortistatin
CTNS cystinosin, lysosomal cystine transporter
DBN1 drebrin 1
DSCAM Down syndrome cell adhesion molecule
EDRF1 erythroid differentiation regulatory factor 1
EGR1 early growth response 1
ELF4 E74-like factor 4 (ets domain transcription factor)
ENO2 enolase 2 (gamma, neuronal)
ERCC4 excision repair cross-complementation group 4
FBXL8 F-box and leucine-rich repeat protein 8
FER1L4 fer-1-like family member 4, pseudogene (functional)
FTO fat mass and obesity associated
FXR2 fragile X mental retardation, autosomal homolog 2
FZD7 frizzled class receptor 7
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GADD45G growth arrest and DNA-damage-inducible, gamma
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GSAP gamma-secretase activating protein
GSTP1 glutathione S-transferase pi 1
GTDC1 glycosyltransferase-like domain containing 1
HAO2 hydroxyacid oxidase 2 (long chain)
HMOX1 heme oxygenase 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGHA1 immunoglobulin heavy constant alpha 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IQCE IQ motif containing E
ITGA8 integrin, alpha 8
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KDM5A lysine (K)-specific demethylase 5A
KIAA0355 KIAA0355
KIF5C kinesin family member 5C
LHB luteinizing hormone beta polypeptide
MARC2 mitochondrial amidoxime reducing component 2
MBD3 methyl-CpG binding domain protein 3
MED6 mediator complex subunit 6
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO1F myosin IF
NPFFR1 neuropeptide FF receptor 1
ORC5 origin recognition complex, subunit 5
PAWR PRKC, apoptosis, WT1, regulator
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PVR poliovirus receptor
PVRL3 poliovirus receptor-related 3
RELN reelin
RIN3 Ras and Rab interactor 3
RNF39 ring finger protein 39
RPAP2 RNA polymerase II associated protein 2
RPH3AL rabphilin 3A-like (without C2 domains)
RPS14 ribosomal protein S14
RRBP1 ribosome binding protein 1
SIX2 SIX homeobox 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPATA5L1 spermatogenesis associated 5-like 1
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD3 StAR-related lipid transfer (START) domain containing 3
SYNGR1 synaptogyrin 1
TBC1D5 TBC1 domain family, member 5
TET3 tet methylcytosine dioxygenase 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMC5 transmembrane channel-like 5
TMPRSS2 transmembrane protease, serine 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNK1 tyrosine kinase, non-receptor, 1
TRAPPC10 trafficking protein particle complex 10
TREX1 three prime repair exonuclease 1
TYMS thymidylate synthetase
UBOX5 U-box domain containing 5
VIPR1 vasoactive intestinal peptide receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDR55 WD repeat domain 55
ZNF137P zinc finger protein 137, pseudogene
ZNF16 zinc finger protein 16
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABCB7 ATP-binding cassette, sub-family B (MDR/TAP), member 7
ABLIM3 actin binding LIM protein family, member 3
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF80 chromosome 11 open reading frame 80
C17ORF70 chromosome 17 open reading frame 70
C5 complement component 5
CASKIN2 CASK interacting protein 2
CASZ1 castor zinc finger 1
CCNT1 cyclin T1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDR2L cerebellar degeneration-related protein 2-like
CHKB choline kinase beta
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DOCK1 dedicator of cytokinesis 1
DVL1 dishevelled segment polarity protein 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFCAB2 EF-hand calcium binding domain 2
EFHD2 EF-hand domain family, member D2
EIF5A2 eukaryotic translation initiation factor 5A2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM127B family with sequence similarity 127, member B
FAM155B family with sequence similarity 155, member B
FBXL15 F-box and leucine-rich repeat protein 15
FKBP10 FK506 binding protein 10, 65 kDa
FOSL1 FOS-like antigen 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GPATCH2L G patch domain containing 2-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MBIP MAP3K12 binding inhibitory protein 1
MBTD1 mbt domain containing 1
MEIS1 Meis homeobox 1
MTA2 metastasis associated 1 family, member 2
MYBBP1A MYB binding protein (P160) 1a
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NCAM2 neural cell adhesion molecule 2
NCSTN nicastrin
NRGN neurogranin (protein kinase C substrate, RC3)
PCNXL4 pecanex-like 4 (Drosophila)
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGM1 phosphoglucomutase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PILRB paired immunoglobin-like type 2 receptor beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLD3 phospholipase D family, member 3
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PPOX protoporphyrinogen oxidase
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PTBP2 polypyrimidine tract binding protein 2
PTTG3P pituitary tumor-transforming 3, pseudogene
PYCRL pyrroline-5-carboxylate reductase-like
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RWDD3 RWD domain containing 3
SCML2 sex comb on midleg-like 2 (Drosophila)
SCPEP1 serine carboxypeptidase 1
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SLC25A40 solute carrier family 25, member 40
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNUPN snurportin 1
SOX12 SRY (sex determining region Y)-box 12
SUSD6 sushi domain containing 6
TCTN1 tectonic family member 1
TM7SF3 transmembrane 7 superfamily member 3
TMSB15A thymosin beta 15a
TRABD TraB domain containing
TRAF5 TNF receptor-associated factor 5
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBGCP5 tubulin, gamma complex associated protein 5
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
VASH2 vasohibin 2
WDR91 WD repeat domain 91
ZDHHC18 zinc finger, DHHC-type containing 18
ZFP30 ZFP30 zinc finger protein
ZFP69B ZFP69 zinc finger protein B
ZNF273 zinc finger protein 273
ZNF324 zinc finger protein 324
ZNF432 zinc finger protein 432