| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the noscapine-2745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APP | amyloid beta (A4) precursor protein |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATXN1 | ataxin 1 |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTG2 | BTG family, member 2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP350 | centrosomal protein 350kDa |
| CREM | cAMP responsive element modulator |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ELAC2 | elaC ribonuclease Z 2 |
| EMID1 | EMI domain containing 1 |
| ERCC1 | excision repair cross-complementation group 1 |
| FAM89B | family with sequence similarity 89, member B |
| FBXO41 | F-box protein 41 |
| FRMD4B | FERM domain containing 4B |
| FUS | FUS RNA binding protein |
| GALR2 | galanin receptor 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GOLGA8A | golgin A8 family, member A |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYG2 | glycogenin 2 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HOMER3 | homer scaffolding protein 3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IL1A | interleukin 1, alpha |
| INO80D | INO80 complex subunit D |
| KAT6A | K(lysine) acetyltransferase 6A |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| LBP | lipopolysaccharide binding protein |
| LOC157562 | uncharacterized LOC157562 |
| LRRC14 | leucine rich repeat containing 14 |
| LRRC23 | leucine rich repeat containing 23 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYL10 | myosin, light chain 10, regulatory |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCOA2 | nuclear receptor coactivator 2 |
| NF1 | neurofibromin 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PDE9A | phosphodiesterase 9A |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB6B | RAB6B, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RFXAP | regulatory factor X-associated protein |
| RGS2 | regulator of G-protein signaling 2 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RND1 | Rho family GTPase 1 |
| RPL35A | ribosomal protein L35a |
| RTN2 | reticulon 2 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SH2B1 | SH2B adaptor protein 1 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SNX13 | sorting nexin 13 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STK4 | serine/threonine kinase 4 |
| TAPBP | TAP binding protein (tapasin) |
| TBX19 | T-box 19 |
| TEX40 | testis expressed 40 |
| TLR2 | toll-like receptor 2 |
| TNS1 | tensin 1 |
| TPMT | thiopurine S-methyltransferase |
| TRIM62 | tripartite motif containing 62 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| VIM | vimentin |
| WAPAL | wings apart-like homolog (Drosophila) |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| YIPF2 | Yip1 domain family, member 2 |
| YY2 | YY2 transcription factor |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK3 | cyclin-dependent kinase 3 |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNN2 | calponin 2 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DEAF1 | DEAF1 transcription factor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EGR3 | early growth response 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| EXO5 | exonuclease 5 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FGL1 | fibrinogen-like 1 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GATA4 | GATA binding protein 4 |
| GFI1 | growth factor independent 1 transcription repressor |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMOX1 | heme oxygenase 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL22 | interleukin 22 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0125 | KIAA0125 |
| KLC2 | kinesin light chain 2 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LHX1 | LIM homeobox 1 |
| LHX6 | LIM homeobox 6 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUC3A | mucin 3A, cell surface associated |
| MYBBP1A | MYB binding protein (P160) 1a |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSMR | oncostatin M receptor |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB11B | RAB11B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF123 | ring finger protein 123 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAIP | TRAF interacting protein |
| USP36 | ubiquitin specific peptidase 36 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF160 | zinc finger protein 160 |
| ZNF205 | zinc finger protein 205 |
| ZNF34 | zinc finger protein 34 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF862 | zinc finger protein 862 |