noscapine-2745 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the noscapine-2745 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADGRA2 adhesion G protein-coupled receptor A2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
APP amyloid beta (A4) precursor protein
ATAT1 alpha tubulin acetyltransferase 1
ATXN1 ataxin 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BLZF1 basic leucine zipper nuclear factor 1
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAPZB capping protein (actin filament) muscle Z-line, beta
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP350 centrosomal protein 350kDa
CREM cAMP responsive element modulator
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAC2 elaC ribonuclease Z 2
EMID1 EMI domain containing 1
ERCC1 excision repair cross-complementation group 1
FAM89B family with sequence similarity 89, member B
FBXO41 F-box protein 41
FRMD4B FERM domain containing 4B
FUS FUS RNA binding protein
GALR2 galanin receptor 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GOLGA8A golgin A8 family, member A
GPER1 G protein-coupled estrogen receptor 1
GSK3A glycogen synthase kinase 3 alpha
GYG2 glycogenin 2
HCRP1 hepatocellular carcinoma-related HCRP1
HOMER3 homer scaffolding protein 3
HPS1 Hermansky-Pudlak syndrome 1
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IL1A interleukin 1, alpha
INO80D INO80 complex subunit D
KAT6A K(lysine) acetyltransferase 6A
KATNB1 katanin p80 (WD repeat containing) subunit B 1
LBP lipopolysaccharide binding protein
LOC157562 uncharacterized LOC157562
LRRC14 leucine rich repeat containing 14
LRRC23 leucine rich repeat containing 23
MAPK14 mitogen-activated protein kinase 14
MARK4 MAP/microtubule affinity-regulating kinase 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MKNK2 MAP kinase interacting serine/threonine kinase 2
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL10 myosin, light chain 10, regulatory
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OSBPL10 oxysterol binding protein-like 10
PDE9A phosphodiesterase 9A
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLK3 polo-like kinase 3
PML promyelocytic leukemia
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP5C protein phosphatase 5, catalytic subunit
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB6B RAB6B, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFXAP regulatory factor X-associated protein
RGS2 regulator of G-protein signaling 2
RIC8B RIC8 guanine nucleotide exchange factor B
RND1 Rho family GTPase 1
RPL35A ribosomal protein L35a
RTN2 reticulon 2
RUFY3 RUN and FYVE domain containing 3
SH2B1 SH2B adaptor protein 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNX13 sorting nexin 13
SOS2 son of sevenless homolog 2 (Drosophila)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STK4 serine/threonine kinase 4
TAPBP TAP binding protein (tapasin)
TBX19 T-box 19
TEX40 testis expressed 40
TLR2 toll-like receptor 2
TNS1 tensin 1
TPMT thiopurine S-methyltransferase
TRIM62 tripartite motif containing 62
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VIM vimentin
WAPAL wings apart-like homolog (Drosophila)
WDFY3 WD repeat and FYVE domain containing 3
YIPF2 Yip1 domain family, member 2
YY2 YY2 transcription factor
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPL1 zinc finger protein-like 1
ZNF37BP zinc finger protein 37B, pseudogene
ZNF41 zinc finger protein 41

decreased expression

Symbol Name
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA2P3 annexin A2 pseudogene 3
ARPIN actin-related protein 2/3 complex inhibitor
ASPHD1 aspartate beta-hydroxylase domain containing 1
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CNN2 calponin 2
CNR2 cannabinoid receptor 2 (macrophage)
CTNNBIP1 catenin, beta interacting protein 1
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP2 dual specificity phosphatase 2
EGR3 early growth response 3
ERCC4 excision repair cross-complementation group 4
EXO5 exonuclease 5
FAM189A2 family with sequence similarity 189, member A2
FGL1 fibrinogen-like 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ11710 uncharacterized protein FLJ11710
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA4 GATA binding protein 4
GFI1 growth factor independent 1 transcription repressor
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IDI2-AS1 IDI2 antisense RNA 1
IL22 interleukin 22
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0125 KIAA0125
KLC2 kinesin light chain 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
LARP6 La ribonucleoprotein domain family, member 6
LHX1 LIM homeobox 1
LHX6 LIM homeobox 6
MATK megakaryocyte-associated tyrosine kinase
MFSD11 major facilitator superfamily domain containing 11
MRPS18C mitochondrial ribosomal protein S18C
MUC3A mucin 3A, cell surface associated
MYBBP1A MYB binding protein (P160) 1a
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PTDSS2 phosphatidylserine synthase 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11B RAB11B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RFTN1 raftlin, lipid raft linker 1
RNF123 ring finger protein 123
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A9 solute carrier family 12, member 9
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
STARD13 StAR-related lipid transfer (START) domain containing 13
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMPRSS3 transmembrane protease, serine 3
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRAIP TRAF interacting protein
USP36 ubiquitin specific peptidase 36
VEZT vezatin, adherens junctions transmembrane protein
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF205 zinc finger protein 205
ZNF34 zinc finger protein 34
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF862 zinc finger protein 862