noscapine-5851 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the noscapine-5851 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTN3 actinin, alpha 3 (gene/pseudogene)
ALDOB aldolase B, fructose-bisphosphate
ALK anaplastic lymphoma receptor tyrosine kinase
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMC9 armadillo repeat containing 9
ARTN artemin
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BGN biglycan
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C1QTNF3 C1q and tumor necrosis factor related protein 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CELF2 CUGBP, Elav-like family member 2
CHN2 chimerin 2
CISH cytokine inducible SH2-containing protein
COBL cordon-bleu WH2 repeat protein
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DCN decorin
DHODH dihydroorotate dehydrogenase (quinone)
DUSP10 dual specificity phosphatase 10
EDNRA endothelin receptor type A
EFCAB11 EF-hand calcium binding domain 11
EFNB1 ephrin-B1
ELSPBP1 epididymal sperm binding protein 1
EMX1 empty spiracles homeobox 1
FBXO22 F-box protein 22
FLT4 fms-related tyrosine kinase 4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXO4 forkhead box O4
FZD1 frizzled class receptor 1
GNS glucosamine (N-acetyl)-6-sulfatase
GPC3 glypican 3
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRTP1 growth hormone regulated TBC protein 1
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HABP4 hyaluronan binding protein 4
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HCRP1 hepatocellular carcinoma-related HCRP1
HOXA4 homeobox A4
IL22 interleukin 22
INO80B INO80 complex subunit B
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGA10 integrin, alpha 10
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT34 keratin 34, type I
LDLR low density lipoprotein receptor
LMAN1 lectin, mannose-binding, 1
LRMP lymphoid-restricted membrane protein
LRP4 low density lipoprotein receptor-related protein 4
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK10 mitogen-activated protein kinase 10
MDFI MyoD family inhibitor
MTMR7 myotubularin related protein 7
MXD4 MAX dimerization protein 4
NCKIPSD NCK interacting protein with SH3 domain
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NLGN1 neuroligin 1
NLGN4X neuroligin 4, X-linked
PDE4B phosphodiesterase 4B, cAMP-specific
PHF20 PHD finger protein 20
PIGR polymeric immunoglobulin receptor
PLXNB3 plexin B3
PRICKLE3 prickle homolog 3 (Drosophila)
PRMT2IP PRMT2 interacting protein
PTK6 protein tyrosine kinase 6
RARG retinoic acid receptor, gamma
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
SATB2 SATB homeobox 2
SCAND2P SCAN domain containing 2 pseudogene
SCARF1 scavenger receptor class F, member 1
SH2D3A SH2 domain containing 3A
SIAH1 siah E3 ubiquitin protein ligase 1
SIKE1 suppressor of IKBKE 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SORBS2 sorbin and SH3 domain containing 2
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRSF7 serine/arginine-rich splicing factor 7
STAC SH3 and cysteine rich domain
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYT17 synaptotagmin XVII
TLDC1 TBC/LysM-associated domain containing 1
TLN2 talin 2
TMEM121 transmembrane protein 121
TMEM231 transmembrane protein 231
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VWA5A von Willebrand factor A domain containing 5A
XAF1 XIAP associated factor 1
ZFPL1 zinc finger protein-like 1
ZNF423 zinc finger protein 423
ZNF606 zinc finger protein 606

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACVR2A activin A receptor, type IIA
ADAM15 ADAM metallopeptidase domain 15
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASB13 ankyrin repeat and SOCS box containing 13
ATP7B ATPase, Cu++ transporting, beta polypeptide
BANK1 B-cell scaffold protein with ankyrin repeats 1
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C1ORF159 chromosome 1 open reading frame 159
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP6 charged multivesicular body protein 6
CHPF chondroitin polymerizing factor
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIP2 CAP-GLY domain containing linker protein 2
CUL9 cullin 9
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPTOR DEP domain containing MTOR-interacting protein
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EFNA1 ephrin-A1
EFNA3 ephrin-A3
EHF ets homologous factor
ELP3 elongator acetyltransferase complex subunit 3
FGGY FGGY carbohydrate kinase domain containing
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLT8D2 glycosyltransferase 8 domain containing 2
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR1 G protein-coupled receptor 1
HIST1H2AJ histone cluster 1, H2aj
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
IL4R interleukin 4 receptor
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
JUNB jun B proto-oncogene
KATNBL1 katanin p80 subunit B-like 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LAMA5 laminin, alpha 5
LIMS2 LIM and senescent cell antigen-like domains 2
LPAR6 lysophosphatidic acid receptor 6
MCRS1 microspherule protein 1
METRN meteorin, glial cell differentiation regulator
METTL1 methyltransferase like 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTMR14 myotubularin related protein 14
MYO9A myosin IXA
NID2 nidogen 2 (osteonidogen)
NOL12 nucleolar protein 12
NPM3 nucleophosmin/nucleoplasmin 3
ODF2 outer dense fiber of sperm tails 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX3 pre-B-cell leukemia homeobox 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PMCH pro-melanin-concentrating hormone
POLM polymerase (DNA directed), mu
POM121 POM121 transmembrane nucleoporin
PORCN porcupine homolog (Drosophila)
PPT2 palmitoyl-protein thioesterase 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RANBP17 RAN binding protein 17
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF25 ring finger protein 25
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCAMP5 secretory carrier membrane protein 5
SH3BGR SH3 domain binding glutamate-rich protein
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC41A3 solute carrier family 41, member 3
SPEG SPEG complex locus
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TESK2 testis-specific kinase 2
TMEM209 transmembrane protein 209
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
UNC13B unc-13 homolog B (C. elegans)
WDR18 WD repeat domain 18
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZFAND3 zinc finger, AN1-type domain 3
ZFHX3 zinc finger homeobox 3
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF136 zinc finger protein 136
ZNF197 zinc finger protein 197
ZNF253 zinc finger protein 253
ZNF629 zinc finger protein 629