| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the novobiocin-2990 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| APC2 | adenomatosis polyposis coli 2 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) |
| ARTN | artemin |
| ATP9A | ATPase, class II, type 9A |
| BCL2L1 | BCL2-like 1 |
| BEND5 | BEN domain containing 5 |
| BMP7 | bone morphogenetic protein 7 |
| BPI | bactericidal/permeability-increasing protein |
| CASZ1 | castor zinc finger 1 |
| CCDC181 | coiled-coil domain containing 181 |
| CCDC87 | coiled-coil domain containing 87 |
| CCNK | cyclin K |
| CD163 | CD163 molecule |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CEP112 | centrosomal protein 112kDa |
| CFAP74 | cilia and flagella associated protein 74 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRP | C-reactive protein, pentraxin-related |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DOK3 | docking protein 3 |
| EDA | ectodysplasin A |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EMC3 | ER membrane protein complex subunit 3 |
| EPO | erythropoietin |
| GLRX3 | glutaredoxin 3 |
| GMPR | guanosine monophosphate reductase |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLA-F | major histocompatibility complex, class I, F |
| HOXB1 | homeobox B1 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IL36RN | interleukin 36 receptor antagonist |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KHK | ketohexokinase (fructokinase) |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLK10 | kallikrein-related peptidase 10 |
| KRT14 | keratin 14, type I |
| KRT23 | keratin 23, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIMD2 | LIM domain containing 2 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MED14 | mediator complex subunit 14 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MNMIP1 | manchette microtubule inner protein 1 |
| MUC1 | mucin 1, cell surface associated |
| MYBPC2 | myosin binding protein C, fast type |
| MYL10 | myosin, light chain 10, regulatory |
| MYOD1 | myogenic differentiation 1 |
| MYOZ3 | myozenin 3 |
| ONECUT2 | one cut homeobox 2 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| PACRG | PARK2 co-regulated |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PICK1 | protein interacting with PRKCA 1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTHLH | parathyroid hormone-like hormone |
| PVR | poliovirus receptor |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RNF122 | ring finger protein 122 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| ROM1 | retinal outer segment membrane protein 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SIX2 | SIX homeobox 2 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPRR2B | small proline-rich protein 2B |
| TDRD1 | tudor domain containing 1 |
| TEX13A | testis expressed 13A |
| TMEM51 | transmembrane protein 51 |
| TMEM53 | transmembrane protein 53 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TPM3 | tropomyosin 3 |
| VAMP5 | vesicle-associated membrane protein 5 |
| VCX2 | variable charge, X-linked 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR1 | WD repeat domain 1 |
| WDR59 | WD repeat domain 59 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF154 | zinc finger protein 154 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADGB | androglobin |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AKTIP | AKT interacting protein |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| BNC2 | basonuclin 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP72 | centrosomal protein 72kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CST1 | cystatin SN |
| CTSD | cathepsin D |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DPYS | dihydropyrimidinase |
| EBF2 | early B-cell factor 2 |
| FHIT | fragile histidine triad |
| FHL3 | four and a half LIM domains 3 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HDAC7 | histone deacetylase 7 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3H | histone cluster 1, H3h |
| HOXC8 | homeobox C8 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFT54 | intraflagellar transport 54 |
| IL2 | interleukin 2 |
| JAM3 | junctional adhesion molecule 3 |
| JPH3 | junctophilin 3 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0753 | KIAA0753 |
| KIAA1024 | KIAA1024 |
| KIAA1107 | KIAA1107 |
| KPTN | kaptin (actin binding protein) |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LTA | lymphotoxin alpha |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAGEH1 | melanoma antigen family H1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP6D1 | MAP6 domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYH4 | myosin, heavy chain 4, skeletal muscle |
| NCKAP1L | NCK-associated protein 1-like |
| NINJ2 | ninjurin 2 |
| NMUR1 | neuromedin U receptor 1 |
| NNAT | neuronatin |
| PCBP4 | poly(rC) binding protein 4 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLA2G3 | phospholipase A2, group III |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PLS1 | plastin 1 |
| PMP22 | peripheral myelin protein 22 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRSS53 | protease, serine, 53 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB40A | RAB40A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RPAP1 | RNA polymerase II associated protein 1 |
| SCRT1 | scratch family zinc finger 1 |
| SETD1A | SET domain containing 1A |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SRPX | sushi-repeat containing protein, X-linked |
| STAT5A | signal transducer and activator of transcription 5A |
| TAS2R10 | taste receptor, type 2, member 10 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCHH | trichohyalin |
| TFDP3 | transcription factor Dp family, member 3 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM184C | transmembrane protein 184C |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| UNC13A | unc-13 homolog A (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| XAB2 | XPA binding protein 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF155 | zinc finger protein 155 |
| ZNF81 | zinc finger protein 81 |