| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the novobiocin-435 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AAK1 | AP2 associated kinase 1 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| AGFG2 | ArfGAP with FG repeats 2 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP5SL | ATP5S-like |
| BHMT | betaine--homocysteine S-methyltransferase |
| BMP7 | bone morphogenetic protein 7 |
| C21ORF62 | chromosome 21 open reading frame 62 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CARD9 | caspase recruitment domain family, member 9 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC87 | coiled-coil domain containing 87 |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHN2 | chimerin 2 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DMXL2 | Dmx-like 2 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| DVL3 | dishevelled segment polarity protein 3 |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EPOR | erythropoietin receptor |
| ESPN | espin |
| ESR1 | estrogen receptor 1 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXOC6B | exocyst complex component 6B |
| FAM110D | family with sequence similarity 110, member D |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FSTL4 | follistatin-like 4 |
| GALR3 | galanin receptor 3 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B |
| GRK4 | G protein-coupled receptor kinase 4 |
| GYPB | glycophorin B (MNS blood group) |
| HAMP | hepcidin antimicrobial peptide |
| HMBOX1 | homeobox containing 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL18BP | interleukin 18 binding protein |
| IL19 | interleukin 19 |
| IMPACT | impact RWD domain protein |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0125 | KIAA0125 |
| KLK12 | kallikrein-related peptidase 12 |
| KYNU | kynureninase |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MON1B | MON1 secretory trafficking family member B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MST1 | macrophage stimulating 1 |
| MTMR8 | myotubularin related protein 8 |
| MVK | mevalonate kinase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYOZ3 | myozenin 3 |
| NCS1 | neuronal calcium sensor 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NRG1 | neuregulin 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PLBD1 | phospholipase B domain containing 1 |
| PSG2 | pregnancy specific beta-1-glycoprotein 2 |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| PVR | poliovirus receptor |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RECQL5 | RecQ protein-like 5 |
| RNASE3 | ribonuclease, RNase A family, 3 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC26A10 | solute carrier family 26, member 10 |
| SLC38A7 | solute carrier family 38, member 7 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNTG1 | syntrophin, gamma 1 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| STAT4 | signal transducer and activator of transcription 4 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TIPRL | TOR signaling pathway regulator |
| TRAC | T cell receptor alpha constant |
| TUBB1 | tubulin, beta 1 class VI |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WISP1 | WNT1 inducible signaling pathway protein 1 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AMT | aminomethyltransferase |
| ANKRD36B | ankyrin repeat domain 36B |
| ANKRD40 | ankyrin repeat domain 40 |
| ARSF | arylsulfatase F |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H |
| ATXN2 | ataxin 2 |
| AVPR1B | arginine vasopressin receptor 1B |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BSPRY | B-box and SPRY domain containing |
| BTBD2 | BTB (POZ) domain containing 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAV3 | caveolin 3 |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCS | copper chaperone for superoxide dismutase |
| CD40LG | CD40 ligand |
| CETN1 | centrin, EF-hand protein, 1 |
| CHN1 | chimerin 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EDC4 | enhancer of mRNA decapping 4 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FKBP6 | FK506 binding protein 6, 36kDa |
| FOXC1 | forkhead box C1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| HDAC7 | histone deacetylase 7 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRIP3 | HIRA interacting protein 3 |
| HOMER1 | homer scaffolding protein 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IL13 | interleukin 13 |
| IL13RA2 | interleukin 13 receptor, alpha 2 |
| IL36RN | interleukin 36 receptor antagonist |
| IRF8 | interferon regulatory factor 8 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| LGMN | legumain |
| LUC7L | LUC7-like (S. cerevisiae) |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAGEA5 | melanoma antigen family A5 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PALB2 | partner and localizer of BRCA2 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARG | poly (ADP-ribose) glycohydrolase |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PGM5 | phosphoglucomutase 5 |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCD1 | phospholipase C, delta 1 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRPF38B | pre-mRNA processing factor 38B |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP17 | RAN binding protein 17 |
| RGS17 | regulator of G-protein signaling 17 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEPP1 | selenoprotein P, plasma, 1 |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SMYD5 | SMYD family member 5 |
| SRPK3 | SRSF protein kinase 3 |
| STAB2 | stabilin 2 |
| STK16 | serine/threonine kinase 16 |
| T | T, brachyury homolog (mouse) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TG | thyroglobulin |
| TLR5 | toll-like receptor 5 |
| TMEM127 | transmembrane protein 127 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM25 | tripartite motif containing 25 |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TYK2 | tyrosine kinase 2 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR91 | WD repeat domain 91 |
| ZFR2 | zinc finger RNA binding protein 2 |
| ZNF652 | zinc finger protein 652 |