novobiocin-435 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

194 genes differentially expressed following the novobiocin-435 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AAK1 AP2 associated kinase 1
ACSS3 acyl-CoA synthetase short-chain family member 3
AGFG2 ArfGAP with FG repeats 2
AHDC1 AT hook, DNA binding motif, containing 1
ANKLE2 ankyrin repeat and LEM domain containing 2
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP5SL ATP5S-like
BHMT betaine--homocysteine S-methyltransferase
BMP7 bone morphogenetic protein 7
C21ORF62 chromosome 21 open reading frame 62
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CARD9 caspase recruitment domain family, member 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC87 coiled-coil domain containing 87
CCL13 chemokine (C-C motif) ligand 13
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDRT1 CMT1A duplicated region transcript 1
CHN2 chimerin 2
CPA3 carboxypeptidase A3 (mast cell)
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCR3 chemokine (C-X-C motif) receptor 3
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DCLRE1B DNA cross-link repair 1B
DMXL2 Dmx-like 2
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DND1 DND microRNA-mediated repression inhibitor 1
DVL3 dishevelled segment polarity protein 3
EFNB3 ephrin-B3
EGR1 early growth response 1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
EPOR erythropoietin receptor
ESPN espin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXOC6B exocyst complex component 6B
FAM110D family with sequence similarity 110, member D
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FSTL4 follistatin-like 4
GALR3 galanin receptor 3
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK4 G protein-coupled receptor kinase 4
GYPB glycophorin B (MNS blood group)
HAMP hepcidin antimicrobial peptide
HMBOX1 homeobox containing 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IL18BP interleukin 18 binding protein
IL19 interleukin 19
IMPACT impact RWD domain protein
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0125 KIAA0125
KLK12 kallikrein-related peptidase 12
KYNU kynureninase
LOC100286895 cell division cycle 27 homolog pseudogene
MAU2 MAU2 sister chromatid cohesion factor
MOGAT2 monoacylglycerol O-acyltransferase 2
MON1B MON1 secretory trafficking family member B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MST1 macrophage stimulating 1
MTMR8 myotubularin related protein 8
MVK mevalonate kinase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYOZ3 myozenin 3
NCS1 neuronal calcium sensor 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRG1 neuregulin 1
PDE4DIP phosphodiesterase 4D interacting protein
PLBD1 phospholipase B domain containing 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PTPRA protein tyrosine phosphatase, receptor type, A
PVR poliovirus receptor
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RC3H2 ring finger and CCCH-type domains 2
RECQL5 RecQ protein-like 5
RNASE3 ribonuclease, RNase A family, 3
SAG S-antigen; retina and pineal gland (arrestin)
SBNO1 strawberry notch homolog 1 (Drosophila)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SEZ6L seizure related 6 homolog (mouse)-like
SIDT2 SID1 transmembrane family, member 2
SLC26A10 solute carrier family 26, member 10
SLC38A7 solute carrier family 38, member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNTG1 syntrophin, gamma 1
SPG20 spastic paraplegia 20 (Troyer syndrome)
STAT4 signal transducer and activator of transcription 4
TESPA1 thymocyte expressed, positive selection associated 1
TIPRL TOR signaling pathway regulator
TRAC T cell receptor alpha constant
TUBB1 tubulin, beta 1 class VI
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
WISP1 WNT1 inducible signaling pathway protein 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
AMT aminomethyltransferase
ANKRD36B ankyrin repeat domain 36B
ANKRD40 ankyrin repeat domain 40
ARSF arylsulfatase F
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATXN2 ataxin 2
AVPR1B arginine vasopressin receptor 1B
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BSPRY B-box and SPRY domain containing
BTBD2 BTB (POZ) domain containing 2
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAV3 caveolin 3
CCBL2 cysteine conjugate-beta lyase 2
CCS copper chaperone for superoxide dismutase
CD40LG CD40 ligand
CETN1 centrin, EF-hand protein, 1
CHN1 chimerin 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLTCL1 clathrin, heavy chain-like 1
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EDC4 enhancer of mRNA decapping 4
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPX eosinophil peroxidase
ERN2 endoplasmic reticulum to nucleus signaling 2
FKBP6 FK506 binding protein 6, 36kDa
FOXC1 forkhead box C1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
HDAC7 histone deacetylase 7
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRIP3 HIRA interacting protein 3
HOMER1 homer scaffolding protein 1
HP1BP3 heterochromatin protein 1, binding protein 3
IL13 interleukin 13
IL13RA2 interleukin 13 receptor, alpha 2
IL36RN interleukin 36 receptor antagonist
IRF8 interferon regulatory factor 8
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LGMN legumain
LUC7L LUC7-like (S. cerevisiae)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAGEA5 melanoma antigen family A5
MAGOHB mago-nashi homolog B (Drosophila)
MAPKBP1 mitogen-activated protein kinase binding protein 1
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OVGP1 oviductal glycoprotein 1, 120kDa
PALB2 partner and localizer of BRCA2
PAQR6 progestin and adipoQ receptor family member VI
PARG poly (ADP-ribose) glycohydrolase
PFAS phosphoribosylformylglycinamidine synthase
PGM5 phosphoglucomutase 5
PGS1 phosphatidylglycerophosphate synthase 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLCD1 phospholipase C, delta 1
PNMA3 paraneoplastic Ma antigen 3
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPP4C protein phosphatase 4, catalytic subunit
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRPF38B pre-mRNA processing factor 38B
PTPRS protein tyrosine phosphatase, receptor type, S
QTRT1 queuine tRNA-ribosyltransferase 1
RANBP17 RAN binding protein 17
RGS17 regulator of G-protein signaling 17
RPL23AP7 ribosomal protein L23a pseudogene 7
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEPP1 selenoprotein P, plasma, 1
SH3GL1 SH3-domain GRB2-like 1
SMYD5 SMYD family member 5
SRPK3 SRSF protein kinase 3
STAB2 stabilin 2
STK16 serine/threonine kinase 16
T T, brachyury homolog (mouse)
TCEA2 transcription elongation factor A (SII), 2
TG thyroglobulin
TLR5 toll-like receptor 5
TMEM127 transmembrane protein 127
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TOE1 target of EGR1, member 1 (nuclear)
TRAPPC12 trafficking protein particle complex 12
TRIM25 tripartite motif containing 25
TSLIG2 tRNA splicing ligase complex subunit 2
TYK2 tyrosine kinase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR91 WD repeat domain 91
ZFR2 zinc finger RNA binding protein 2
ZNF652 zinc finger protein 652