| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the novobiocin-437 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APC | adenomatous polyposis coli |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| B9D1 | B9 protein domain 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CADM3 | cell adhesion molecule 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CD44 | CD44 molecule (Indian blood group) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CKB | creatine kinase, brain |
| CLCC1 | chloride channel CLIC-like 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CUL4B | cullin 4B |
| DAPK1 | death-associated protein kinase 1 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| EIF5B | eukaryotic translation initiation factor 5B |
| ENOSF1 | enolase superfamily member 1 |
| EPX | eosinophil peroxidase |
| ESR1 | estrogen receptor 1 |
| F8 | coagulation factor VIII, procoagulant component |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FLOT1 | flotillin 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HFE | hemochromatosis |
| HLA-G | major histocompatibility complex, class I, G |
| HNF1A | HNF1 homeobox A |
| HOXB1 | homeobox B1 |
| HPSE | heparanase |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IL1B | interleukin 1, beta |
| INO80B | INO80 complex subunit B |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KIAA0141 | KIAA0141 |
| KLHL9 | kelch-like family member 9 |
| KRT6B | keratin 6B, type II |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MED18 | mediator complex subunit 18 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MT4 | metallothionein 4 |
| MYCBP | MYC binding protein |
| MYL10 | myosin, light chain 10, regulatory |
| NDRG2 | NDRG family member 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PARVA | parvin, alpha |
| PAX8 | paired box 8 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKCA | protein kinase C, alpha |
| RAB23 | RAB23, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RAPGEF3 | Rap guanine nucleotide exchange factor (GEF) 3 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RPL35A | ribosomal protein L35a |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SIK3 | SIK family kinase 3 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 |
| SMAD6 | SMAD family member 6 |
| SNX19 | sorting nexin 19 |
| SRRT | serrate, RNA effector molecule |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| TMEM161A | transmembrane protein 161A |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSC22D3 | TSC22 domain family, member 3 |
| UBE3A | ubiquitin protein ligase E3A |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF24 | zinc finger protein 24 |
| ZNF33B | zinc finger protein 33B |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACYP2 | acylphosphatase 2, muscle type |
| AIM2 | absent in melanoma 2 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BDKRB1 | bradykinin receptor B1 |
| BEAN1 | brain expressed, associated with NEDD4, 1 |
| BSG | basigin (Ok blood group) |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C20ORF195 | chromosome 20 open reading frame 195 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPT | centromere protein T |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCA1 | chloride channel accessory 1 |
| CLDN17 | claudin 17 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CNTN1 | contactin 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CRLF2 | cytokine receptor-like factor 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CRYAB | crystallin, alpha B |
| CSN2 | casein beta |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DYSF | dysferlin |
| EVPL | envoplakin |
| FANCF | Fanconi anemia, complementation group F |
| FOXC1 | forkhead box C1 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GDF2 | growth differentiation factor 2 |
| GDF3 | growth differentiation factor 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GP9 | glycoprotein IX (platelet) |
| GPR27 | G protein-coupled receptor 27 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFNA4 | interferon, alpha 4 |
| IL36RN | interleukin 36 receptor antagonist |
| IL4R | interleukin 4 receptor |
| KIF13B | kinesin family member 13B |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LEFTY1 | left-right determination factor 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MEFV | Mediterranean fever |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MLXIPL | MLX interacting protein-like |
| MOB3B | MOB kinase activator 3B |
| MPPED1 | metallophosphoesterase domain containing 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OLFML2A | olfactomedin-like 2A |
| PAX1 | paired box 1 |
| PCTP | phosphatidylcholine transfer protein |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PQLC2 | PQ loop repeat containing 2 |
| PQLC3 | PQ loop repeat containing 3 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF121 | ring finger protein 121 |
| RNF39 | ring finger protein 39 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC38A3 | solute carrier family 38, member 3 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPEF1 | sperm flagellar 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS2 | thrombospondin 2 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM57 | transmembrane protein 57 |
| TMEM59L | transmembrane protein 59-like |
| TMEM8A | transmembrane protein 8A |
| TNS2 | tensin 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN1 | tetraspanin 1 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 |
| ZDHHC8P1 | zinc finger, DHHC-type containing 8 pseudogene 1 |
| ZNF408 | zinc finger protein 408 |