| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the novobiocin-499 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| AEN | apoptosis enhancing nuclease |
| ALX3 | ALX homeobox 3 |
| ATXN2L | ataxin 2-like |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| CAV3 | caveolin 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CD44 | CD44 molecule (Indian blood group) |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEP57 | centrosomal protein 57kDa |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CFAP70 | cilia and flagella associated protein 70 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CTTN | cortactin |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP2C19 | cytochrome P450, family 2, subfamily C, polypeptide 19 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 |
| CYTH4 | cytohesin 4 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DIXDC1 | DIX domain containing 1 |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| DPEP1 | dipeptidase 1 (renal) |
| ECE2 | endothelin converting enzyme 2 |
| EPHB1 | EPH receptor B1 |
| EPOR | erythropoietin receptor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM134B | family with sequence similarity 134, member B |
| FAM188A | family with sequence similarity 188, member A |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| GAGE3 | G antigen 3 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| GMDS | GDP-mannose 4,6-dehydratase |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GYPB | glycophorin B (MNS blood group) |
| HBBP1 | hemoglobin, beta pseudogene 1 |
| HLA-F | major histocompatibility complex, class I, F |
| HMGA1 | high mobility group AT-hook 1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL13 | interleukin 13 |
| IRS4 | insulin receptor substrate 4 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| KIAA1614 | KIAA1614 |
| KLK8 | kallikrein-related peptidase 8 |
| KRT75 | keratin 75, type II |
| LETM1 | leucine zipper-EF-hand containing transmembrane protein 1 |
| LGMN | legumain |
| LOC440895 | two pore channel 3 pseudogene |
| LOC647070 | uncharacterized LOC647070 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MRC2 | mannose receptor, C type 2 |
| MYL10 | myosin, light chain 10, regulatory |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NDRG2 | NDRG family member 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRP2 | neuropilin 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIP | prolactin-induced protein |
| PLXNA2 | plexin A2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKD3 | protein kinase D3 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBM5 | RNA binding motif protein 5 |
| RGSL1 | regulator of G-protein signaling like 1 |
| RHAG | Rh-associated glycoprotein |
| RHOD | ras homolog family member D |
| RORC | RAR-related orphan receptor C |
| RPL10 | ribosomal protein L10 |
| SH2D1A | SH2 domain containing 1A |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| STK19 | serine/threonine kinase 19 |
| STX2 | syntaxin 2 |
| TGM3 | transglutaminase 3 |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMEM177 | transmembrane protein 177 |
| TRIM10 | tripartite motif containing 10 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSPYL2 | TSPY-like 2 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ADAMTSL4 | ADAMTS-like 4 |
| ADIRF | adipogenesis regulatory factor |
| ANXA6 | annexin A6 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BHMT | betaine--homocysteine S-methyltransferase |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA11 | carbonic anhydrase XI |
| CBX7 | chromobox homolog 7 |
| CENPE | centromere protein E, 312kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CFAP69 | cilia and flagella associated protein 69 |
| CLCA1 | chloride channel accessory 1 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDN15 | claudin 15 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CRYAA | crystallin, alpha A |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DCPS | decapping enzyme, scavenger |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DRP2 | dystrophin related protein 2 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVPL | envoplakin |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM153A | family with sequence similarity 153, member A |
| FAM192A | family with sequence similarity 192, member A |
| FANCF | Fanconi anemia, complementation group F |
| FCN3 | ficolin (collagen/fibrinogen domain containing) 3 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXN2 | forkhead box N2 |
| FTCD | formimidoyltransferase cyclodeaminase |
| FXYD6 | FXYD domain containing ion transport regulator 6 |
| G6PC2 | glucose-6-phosphatase, catalytic, 2 |
| GALR3 | galanin receptor 3 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HIRA | histone cell cycle regulator |
| HPGDS | hematopoietic prostaglandin D synthase |
| IRF9 | interferon regulatory factor 9 |
| JOSD1 | Josephin domain containing 1 |
| KIF20B | kinesin family member 20B |
| KIFAP3 | kinesin-associated protein 3 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LHX6 | LIM homeobox 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MALL | mal, T-cell differentiation protein-like |
| MAOB | monoamine oxidase B |
| MARK1 | MAP/microtubule affinity-regulating kinase 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC3R | melanocortin 3 receptor |
| MON1B | MON1 secretory trafficking family member B |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NRSN2 | neurensin 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHB3 | protocadherin beta 3 |
| PHOX2A | paired-like homeobox 2a |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| PODNL1 | podocan-like 1 |
| PON3 | paraoxonase 3 |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAI14 | retinoic acid induced 14 |
| RASL10A | RAS-like, family 10, member A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SIL1 | SIL1 nucleotide exchange factor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| SYT2 | synaptotagmin II |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TEX13B | testis expressed 13B |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TMEM127 | transmembrane protein 127 |
| TMEM185B | transmembrane protein 185B |
| TNS4 | tensin 4 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TREML2 | triggering receptor expressed on myeloid cells-like 2 |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| USP20 | ubiquitin specific peptidase 20 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |