novobiocin-576 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the novobiocin-576 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADAM23 ADAM metallopeptidase domain 23
AIF1 allograft inflammatory factor 1
AMPD3 adenosine monophosphate deaminase 3
APOA4 apolipoprotein A-IV
ARSF arylsulfatase F
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BEST2 bestrophin 2
BIRC5 baculoviral IAP repeat containing 5
BMP10 bone morphogenetic protein 10
C1ORF54 chromosome 1 open reading frame 54
C22ORF31 chromosome 22 open reading frame 31
C5 complement component 5
CA6 carbonic anhydrase VI
CAV3 caveolin 3
CCNJL cyclin J-like
CCR8 chemokine (C-C motif) receptor 8
CD6 CD6 molecule
CHERP calcium homeostasis endoplasmic reticulum protein
CHN2 chimerin 2
COX5B cytochrome c oxidase subunit Vb
CPT1A carnitine palmitoyltransferase 1A (liver)
CSN2 casein beta
CTTN cortactin
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DLX4 distal-less homeobox 4
EIF5A eukaryotic translation initiation factor 5A
EPAS1 endothelial PAS domain protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GDF10 growth differentiation factor 10
GIMAP5 GTPase, IMAP family member 5
GLRX3 glutaredoxin 3
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HCG9 HLA complex group 9 (non-protein coding)
HDLBP high density lipoprotein binding protein
HFE hemochromatosis
HIPK2 homeodomain interacting protein kinase 2
HOXB1 homeobox B1
HOXD1 homeobox D1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1B interleukin 1, beta
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KIAA1045 KIAA1045
KLF6 Kruppel-like factor 6
KLK13 kallikrein-related peptidase 13
LOC647070 uncharacterized LOC647070
LONRF3 LON peptidase N-terminal domain and ring finger 3
LRRN3 leucine rich repeat neuronal 3
LRTM1 leucine-rich repeats and transmembrane domains 1
MAGEB2 melanoma antigen family B2
MEFV Mediterranean fever
MOGAT2 monoacylglycerol O-acyltransferase 2
MTERF4 mitochondrial transcription termination factor 4
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NCF2 neutrophil cytosolic factor 2
NCKIPSD NCK interacting protein with SH3 domain
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARVA parvin, alpha
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PICK1 protein interacting with PRKCA 1
PIWIL2 piwi-like RNA-mediated gene silencing 2
PSG11 pregnancy specific beta-1-glycoprotein 11
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTK2B protein tyrosine kinase 2 beta
RASIP1 Ras interacting protein 1
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPL14 ribosomal protein L14
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SET SET nuclear proto-oncogene
SH3BP2 SH3-domain binding protein 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNAI1 snail family zinc finger 1
SP100 SP100 nuclear antigen
SPN sialophorin
SPRR1B small proline-rich protein 1B
SSTR4 somatostatin receptor 4
TLN1 talin 1
TLN2 talin 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNXB tenascin XB
TPMT thiopurine S-methyltransferase
TSPO2 translocator protein 2
USP29 ubiquitin specific peptidase 29
WDR19 WD repeat domain 19
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF236 zinc finger protein 236

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
ACD adrenocortical dysplasia homolog (mouse)
ACOT9 acyl-CoA thioesterase 9
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ADGRL2 adhesion G protein-coupled receptor L2
AGBL5 ATP/GTP binding protein-like 5
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
AKTIP AKT interacting protein
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
BCL7B B-cell CLL/lymphoma 7B
C14ORF79 chromosome 14 open reading frame 79
C2CD5 C2 calcium-dependent domain containing 5
C4BPA complement component 4 binding protein, alpha
C7ORF43 chromosome 7 open reading frame 43
CA7 carbonic anhydrase VII
CBR1 carbonyl reductase 1
CCP110 centriolar coiled coil protein 110kDa
CD2AP CD2-associated protein
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGKD diacylglycerol kinase, delta 130kDa
DHDDS dehydrodolichyl diphosphate synthase
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DLK2 delta-like 2 homolog (Drosophila)
DNAAF2 dynein, axonemal, assembly factor 2
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EFNA1 ephrin-A1
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
EPHA4 EPH receptor A4
EXOC3 exocyst complex component 3
FAM188A family with sequence similarity 188, member A
FAM3C family with sequence similarity 3, member C
FANCF Fanconi anemia, complementation group F
FASTKD5 FAST kinase domains 5
FGF4 fibroblast growth factor 4
FKBP2 FK506 binding protein 2, 13kDa
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXD1 forkhead box D1
FSD1 fibronectin type III and SPRY domain containing 1
GALR3 galanin receptor 3
GBAS glioblastoma amplified sequence
GLMN glomulin, FKBP associated protein
GPATCH1 G patch domain containing 1
GRAMD3 GRAM domain containing 3
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HIST1H3G histone cluster 1, H3g
HIST1H4J histone cluster 1, H4j
JOSD1 Josephin domain containing 1
LGMN legumain
LTN1 listerin E3 ubiquitin protein ligase 1
LYPD1 LY6/PLAUR domain containing 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MED17 mediator complex subunit 17
MEX3C mex-3 RNA binding family member C
NPDC1 neural proliferation, differentiation and control, 1
NPTX1 neuronal pentraxin I
NPY1R neuropeptide Y receptor Y1
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
NUP93 nucleoporin 93kDa
PADI1 peptidyl arginine deiminase, type I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PELP1 proline, glutamate and leucine rich protein 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLD2 phospholipase D2
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PODXL2 podocalyxin-like 2
PORCN porcupine homolog (Drosophila)
PRCP prolylcarboxypeptidase (angiotensinase C)
PRKCD protein kinase C, delta
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRLH prolactin releasing hormone
REC8 REC8 meiotic recombination protein
RSBN1 round spermatid basic protein 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SIL1 SIL1 nucleotide exchange factor
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC35E3 solute carrier family 35, member E3
SNX10 sorting nexin 10
SNX17 sorting nexin 17
SNX6 sorting nexin 6
SPDL1 spindle apparatus coiled-coil protein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TCEA2 transcription elongation factor A (SII), 2
THOC1 THO complex 1
TM7SF3 transmembrane 7 superfamily member 3
TSPYL2 TSPY-like 2
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR13 WD repeat domain 13
ZFP36 ZFP36 ring finger protein
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF107 zinc finger protein 107