| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the novobiocin-632 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ADD2 | adducin 2 (beta) |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARG2 | arginase 2 |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATF6B | activating transcription factor 6 beta |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BTBD2 | BTB (POZ) domain containing 2 |
| CCDC130 | coiled-coil domain containing 130 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHD1L | chromodomain helicase DNA binding protein 1-like |
| CHPF2 | chondroitin polymerizing factor 2 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNTN1 | contactin 1 |
| COPS8 | COP9 signalosome subunit 8 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) |
| DARS | aspartyl-tRNA synthetase |
| DEDD | death effector domain containing |
| DIO3 | deiodinase, iodothyronine, type III |
| DOCK1 | dedicator of cytokinesis 1 |
| EDC3 | enhancer of mRNA decapping 3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM182B | family with sequence similarity 182, member B |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR1 | fibroblast growth factor receptor 1 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GM2A | GM2 ganglioside activator |
| GRM8 | glutamate receptor, metabotropic 8 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| IFNA17 | interferon, alpha 17 |
| IL1RN | interleukin 1 receptor antagonist |
| INO80B | INO80 complex subunit B |
| INSIG1 | insulin induced gene 1 |
| ISCA1 | iron-sulfur cluster assembly 1 |
| KDM2A | lysine (K)-specific demethylase 2A |
| KIAA1033 | KIAA1033 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LETMD1 | LETM1 domain containing 1 |
| LOC647070 | uncharacterized LOC647070 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MINK1 | misshapen-like kinase 1 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEFL | neurofilament, light polypeptide |
| NET1 | neuroepithelial cell transforming 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OXLD1 | oxidoreductase-like domain containing 1 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PPCS | phosphopantothenoylcysteine synthetase |
| PRUNE | prune exopolyphosphatase |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RPL10 | ribosomal protein L10 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SETD1B | SET domain containing 1B |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SLC35E1 | solute carrier family 35, member E1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SNX15 | sorting nexin 15 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SPAG9 | sperm associated antigen 9 |
| SPOP | speckle-type POZ protein |
| STX12 | syntaxin 12 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TCF3 | transcription factor 3 |
| TMEM161A | transmembrane protein 161A |
| TMEM186 | transmembrane protein 186 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TP53BP1 | tumor protein p53 binding protein 1 |
| TRIM66 | tripartite motif containing 66 |
| U2SURP | U2 snRNP-associated SURP domain containing |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| UBQLN4 | ubiquilin 4 |
| VPS52 | vacuolar protein sorting 52 homolog (S. cerevisiae) |
| WASF1 | WAS protein family, member 1 |
| ZFAND1 | zinc finger, AN1-type domain 1 |
| ZMYM1 | zinc finger, MYM-type 1 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ADCK3 | aarF domain containing kinase 3 |
| AEN | apoptosis enhancing nuclease |
| ANKRD40 | ankyrin repeat domain 40 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) |
| AXIN1 | axin 1 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBC3 | BCL2 binding component 3 |
| BCAR3 | breast cancer anti-estrogen resistance 3 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CDK6 | cyclin-dependent kinase 6 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CLDN17 | claudin 17 |
| CNPY3 | canopy FGF signaling regulator 3 |
| CRBN | cereblon |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DCLRE1A | DNA cross-link repair 1A |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EPHA4 | EPH receptor A4 |
| ERF | Ets2 repressor factor |
| EXOSC9 | exosome component 9 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM153A | family with sequence similarity 153, member A |
| FAM46A | family with sequence similarity 46, member A |
| FAM89B | family with sequence similarity 89, member B |
| FBXO3 | F-box protein 3 |
| FBXO31 | F-box protein 31 |
| FGF13 | fibroblast growth factor 13 |
| FOXN2 | forkhead box N2 |
| GOLGA8B | golgin A8 family, member B |
| H2BFS | H2B histone family, member S (pseudogene) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIRA | histone cell cycle regulator |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTRA1 | HtrA serine peptidase 1 |
| IFT81 | intraflagellar transport 81 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| KIAA0319L | KIAA0319-like |
| KIF18B | kinesin family member 18B |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLC2 | kinesin light chain 2 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL21 | kelch-like family member 21 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MAGEA5 | melanoma antigen family A5 |
| MCRS1 | microspherule protein 1 |
| MFF | mitochondrial fission factor |
| MISP | mitotic spindle positioning |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NCAPH | non-SMC condensin I complex, subunit H |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OFD1 | oral-facial-digital syndrome 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| POLR1C | polymerase (RNA) I polypeptide C, 30kDa |
| POU5F1B | POU class 5 homeobox 1B |
| PPOX | protoporphyrinogen oxidase |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAD54L | RAD54-like (S. cerevisiae) |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 |
| STK25 | serine/threonine kinase 25 |
| SUMO4 | small ubiquitin-like modifier 4 |
| TBCC | tubulin folding cofactor C |
| TESK1 | testis-specific kinase 1 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM120B | transmembrane protein 120B |
| TMEM132A | transmembrane protein 132A |
| TMEM165 | transmembrane protein 165 |
| TMEM246 | transmembrane protein 246 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UBQLN2 | ubiquilin 2 |
| UIMC1 | ubiquitin interaction motif containing 1 |
| WDR18 | WD repeat domain 18 |
| WDR46 | WD repeat domain 46 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF143 | zinc finger protein 143 |
| ZNF358 | zinc finger protein 358 |
| ZNF629 | zinc finger protein 629 |
