novobiocin-na Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

702 genes differentially expressed following the novobiocin-na small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CCR3 chemokine (C-C motif) receptor 3 7.22374
EVI5 ecotropic viral integration site 5 6.40962
SMAD9 SMAD family member 9 6.19686
ECI1 enoyl-CoA delta isomerase 1 6.16819
TST thiosulfate sulfurtransferase (rhodanese) 6.05304
HPS6 Hermansky-Pudlak syndrome 6 5.91766
CA12 carbonic anhydrase XII 5.65893
GNPAT glyceronephosphate O-acyltransferase 5.56895
CRK v-crk avian sarcoma virus CT10 oncogene homolog 5.55884
OPRM1 opioid receptor, mu 1 5.5146
DRD4 dopamine receptor D4 5.48837
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) 5.46435
TLR6 toll-like receptor 6 5.45339
CMA1 chymase 1, mast cell 5.4167
ZFHX3 zinc finger homeobox 3 5.41052
CCL27 chemokine (C-C motif) ligand 27 5.37091
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 5.36677
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 5.32613
BEND5 BEN domain containing 5 5.29479
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 5.09236
ZNF460 zinc finger protein 460 5.01277
ADGRE2 adhesion G protein-coupled receptor E2 4.94629
CDH12 cadherin 12, type 2 (N-cadherin 2) 4.91661
MPST mercaptopyruvate sulfurtransferase 4.91561
CCL25 chemokine (C-C motif) ligand 25 4.90743
FGG fibrinogen gamma chain 4.89813
MYH1 myosin, heavy chain 1, skeletal muscle, adult 4.87975
CASP5 caspase 5, apoptosis-related cysteine peptidase 4.86723
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 4.77454
PBOV1 prostate and breast cancer overexpressed 1 4.7707
SMAD5-AS1 SMAD5 antisense RNA 1 4.76558
MMP26 matrix metallopeptidase 26 4.73327
CRYGA crystallin, gamma A 4.64405
RNF24 ring finger protein 24 4.63961
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2 4.63466
KRTAP9-9 keratin associated protein 9-9 4.6179
IL4 interleukin 4 4.58553
ZNF778 zinc finger protein 778 4.55391
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 4.54972
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 4.54689
GFRA3 GDNF family receptor alpha 3 4.54278
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 4.53176
CEP170 centrosomal protein 170kDa 4.4982
RHEBP1 Ras-homolog enriched in brain pseudogene 1 4.48085
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 4.44991
SCIN scinderin 4.43852
LEF1 lymphoid enhancer-binding factor 1 4.43749
NPY2R neuropeptide Y receptor Y2 4.43199
ELOA2 elongin A2 4.42456
FGA fibrinogen alpha chain 4.42344
TPPP3 tubulin polymerization-promoting protein family member 3 4.40834
GUCY2C guanylate cyclase 2C 4.40811
TMEM11 transmembrane protein 11 4.38712
DYNLT3 dynein, light chain, Tctex-type 3 4.38445
MAP7D1 MAP7 domain containing 1 4.37982
SEC14L4 SEC14-like 4 (S. cerevisiae) 4.37776
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 4.37501
RWDD3 RWD domain containing 3 4.37355
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 4.37088
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 4.36579
HOXD10 homeobox D10 4.34857
ALPK1 alpha-kinase 1 4.34107
KRT35 keratin 35, type I 4.32292
CLEC2D C-type lectin domain family 2, member D 4.31819
SLC30A1 solute carrier family 30 (zinc transporter), member 1 4.31351
ANKRD40CL ANKRD40 C-terminal like 4.3064
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene 4.30207
CCDC69 coiled-coil domain containing 69 4.2914
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 4.27978
PHC2 polyhomeotic homolog 2 (Drosophila) 4.26536
BTK Bruton agammaglobulinemia tyrosine kinase 4.2534
CENPBD2P CENPB DNA-binding domains containing 2, pseudogene 4.2322
SLC25A42 solute carrier family 25, member 42 4.23178
EYA1 EYA transcriptional coactivator and phosphatase 1 4.22474
NR5A2 nuclear receptor subfamily 5, group A, member 2 4.20825
ZNF516 zinc finger protein 516 4.19257
ADCY9 adenylate cyclase 9 4.19223
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 4.17572
TUBB1 tubulin, beta 1 class VI 4.17345
OPRK1 opioid receptor, kappa 1 4.17053
PADI2 peptidyl arginine deiminase, type II 4.1695
CLTA clathrin, light chain A 4.14311
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 4.13356
ZNF710 zinc finger protein 710 4.12586
BEX4 brain expressed, X-linked 4 4.11077
CHMP2A charged multivesicular body protein 2A 4.1065
AGO4 argonaute RISC catalytic component 4 4.07019
THAP11 THAP domain containing 11 4.06903
APOH apolipoprotein H (beta-2-glycoprotein I) 4.063
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 4.05748
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 4.0566
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 4.04669
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 4.04663
IGFBP7 insulin-like growth factor binding protein 7 4.02396
GARNL3 GTPase activating Rap/RanGAP domain-like 3 4.00512
DUSP26 dual specificity phosphatase 26 (putative) 3.98276
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 3.97773
CATSPERG catsper channel auxiliary subunit gamma 3.95669
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.95641
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 3.95376
PNMT phenylethanolamine N-methyltransferase 3.94923
SKIC8 SKI8 subunit of superkiller complex 3.91302
EIF5B eukaryotic translation initiation factor 5B 3.90822
RAB13 RAB13, member RAS oncogene family 3.89348
PLCB4 phospholipase C, beta 4 3.87952
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 3.87724
H1-5 H1.5 linker histone, cluster member 3.8584
MTMR7 myotubularin related protein 7 3.85787
KIAA0040 KIAA0040 3.85428
RBM34 RNA binding motif protein 34 3.84408
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 3.81776
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 3.81642
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 3.8088
EPHA3 EPH receptor A3 3.80372
TCP10L3 t-complex 10 like 3, pseudogene 3.79318
HOMER2 homer scaffolding protein 2 3.78988
AMBN ameloblastin (enamel matrix protein) 3.7887
ISG20 interferon stimulated exonuclease gene 20kDa 3.77712
LSAMP limbic system-associated membrane protein 3.77096
NME8 NME/NM23 family member 8 3.75903
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 3.75541
ZNF549 zinc finger protein 549 3.74648
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) 3.73508
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 3.72692
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 3.722
UBB ubiquitin B 3.71712
R3HCC1 R3H domain and coiled-coil containing 1 3.71693
HOXA6 homeobox A6 3.70875
RXFP3 relaxin/insulin-like family peptide receptor 3 3.69593
VWA1 von Willebrand factor A domain containing 1 3.68928
PLA2G1B phospholipase A2, group IB (pancreas) 3.67817
S100A14 S100 calcium binding protein A14 3.67789
TUSC2 tumor suppressor candidate 2 3.67201
PLA2G2F phospholipase A2, group IIF 3.67063
DRD3 dopamine receptor D3 3.66336
DUSP13 dual specificity phosphatase 13 3.65262
VIL1 villin 1 3.64358
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 3.64348
DUSP3 dual specificity phosphatase 3 3.64145
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 3.63585
ARL3 ADP-ribosylation factor-like 3 3.63371
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 3.62742
PCSK5 proprotein convertase subtilisin/kexin type 5 3.62423
WNT4 wingless-type MMTV integration site family, member 4 3.62383
SLC66A3 solute carrier family 66 member 3 3.62101
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) 3.61985
RPS14 ribosomal protein S14 3.60077
TSEN34 TSEN34 tRNA splicing endonuclease subunit 3.58935
LBX1 ladybird homeobox 1 3.58739
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 3.58314
BRSK2 BR serine/threonine kinase 2 3.58156
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 3.57664
TLR2 toll-like receptor 2 3.57564
CXCR1 chemokine (C-X-C motif) receptor 1 3.55859
FRS2 fibroblast growth factor receptor substrate 2 3.55812
MFAP4 microfibrillar-associated protein 4 3.55729
LRRC19 leucine rich repeat containing 19 3.55564
GAS6 growth arrest-specific 6 3.55353
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 3.54729
MOS v-mos Moloney murine sarcoma viral oncogene homolog 3.53734
JPT2 Jupiter microtubule associated homolog 2 3.52899
NR2C2 nuclear receptor subfamily 2, group C, member 2 3.52704
MN1 meningioma (disrupted in balanced translocation) 1 3.52489
PCYT1B phosphate cytidylyltransferase 1, choline, beta 3.52409
CD9 CD9 molecule 3.51889
XPC xeroderma pigmentosum, complementation group C 3.50912
KRT23 keratin 23, type I 3.50032
WBP4 WW domain binding protein 4 3.49363
PLCL1 phospholipase C-like 1 3.49293
RTCA RNA 3'-terminal phosphate cyclase 3.48798
POU3F4 POU class 3 homeobox 4 3.48203
NT5C2 5'-nucleotidase, cytosolic II 3.47644
POU4F3 POU class 4 homeobox 3 3.47063
SLC14A2 solute carrier family 14 (urea transporter), member 2 3.46699
POU6F2 POU class 6 homeobox 2 3.45081
NT5M 5',3'-nucleotidase, mitochondrial 3.45076
HOXB8 homeobox B8 3.44906
IMPG1 interphotoreceptor matrix proteoglycan 1 3.44789
MOCOS molybdenum cofactor sulfurase 3.44498
SOX14 SRY (sex determining region Y)-box 14 3.44305
FOXD2 forkhead box D2 3.4286
SAC3D1 SAC3 domain containing 1 3.42785
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 3.42589
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 3.42446
TOB1 transducer of ERBB2, 1 3.42112
BID BH3 interacting domain death agonist 3.41722
MAPK13 mitogen-activated protein kinase 13 3.41363
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 3.40667
ZNF160 zinc finger protein 160 3.40311
CHUK conserved helix-loop-helix ubiquitous kinase 3.40262
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 3.39576
PHKG2 phosphorylase kinase, gamma 2 (testis) 3.37867
CLIC5 chloride intracellular channel 5 3.37861
PNLIPRP2 pancreatic lipase-related protein 2 3.37745
PLIN3 perilipin 3 3.3694
CYSLTR2 cysteinyl leukotriene receptor 2 3.36864
UTS2 urotensin 2 3.36675
USP36 ubiquitin specific peptidase 36 3.36466
FBXO2 F-box protein 2 3.36429
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 3.35654
ZNF749 zinc finger protein 749 3.35231
KRT20 keratin 20, type I 3.34818
TLX3 T-cell leukemia homeobox 3 3.34786
C1QTNF1 C1q and tumor necrosis factor related protein 1 3.34768
ART1 ADP-ribosyltransferase 1 3.34138
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 3.34024
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 3.33793
UBXN7 UBX domain protein 7 3.33785
RAMP3 receptor (G protein-coupled) activity modifying protein 3 3.33772
CALML4 calmodulin-like 4 3.33571
AKIRIN1 akirin 1 3.32553
GLUL glutamate-ammonia ligase 3.32174
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 3.31592
LCE2B late cornified envelope 2B 3.31043
FBXL14 F-box and leucine-rich repeat protein 14 3.30899
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 3.30605
C22ORF31 chromosome 22 open reading frame 31 3.30347
ANKRD11 ankyrin repeat domain 11 3.30114
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa 3.29622
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 3.29554
PYY peptide YY 3.29288
MAP3K7CL MAP3K7 C-terminal like 3.28757
H2BC14 H2B clustered histone 14 3.28641
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 3.28063
NTN1 netrin 1 3.27926
CD63 CD63 molecule 3.27819
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 3.27386
ERICH1 glutamate-rich 1 3.26994
CXXC4 CXXC finger protein 4 3.26736
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 3.25809
RNF114 ring finger protein 114 3.25342
RAB5IF RAB5 interacting factor 3.25136
IL3RA interleukin 3 receptor, alpha (low affinity) 3.25055
PDCD6 programmed cell death 6 3.24906
LORICRIN loricrin cornified envelope precursor protein 3.24883
TIMP1 TIMP metallopeptidase inhibitor 1 3.24759
LDLRAD4 low density lipoprotein receptor class A domain containing 4 3.24652
TM6SF1 transmembrane 6 superfamily member 1 3.24136
NRTN neurturin 3.23528
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 3.23491
GPA33 glycoprotein A33 (transmembrane) 3.23307
PAQR4 progestin and adipoQ receptor family member IV 3.23262
NPTX2 neuronal pentraxin II 3.23228
GRM3 glutamate receptor, metabotropic 3 3.23025
COPA coatomer protein complex, subunit alpha 3.2264
DNM3 dynamin 3 3.22564
RANBP2 RAN binding protein 2 3.22342
TUT4 terminal uridylyl transferase 4 3.22325
TUFM Tu translation elongation factor, mitochondrial 3.22206
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5 3.22157
OCA2 oculocutaneous albinism II 3.2208
MSTN myostatin 3.21862
CFAP68 cilia and flagella associated protein 68 3.21849
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 3.21312
NALF1 NALCN channel auxiliary factor 1 3.21235
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 3.20192
TRAT1 T cell receptor associated transmembrane adaptor 1 3.20096
DOCK4 dedicator of cytokinesis 4 3.19731
FBXL12 F-box and leucine-rich repeat protein 12 3.19693
IL3 interleukin 3 3.19493
NTSR2 neurotensin receptor 2 3.1926
MYH2 myosin, heavy chain 2, skeletal muscle, adult 3.19008
ADGRG2 adhesion G protein-coupled receptor G2 3.18386
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 3.18146
TAAR5 trace amine associated receptor 5 3.17875
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.1775
GPX7 glutathione peroxidase 7 3.17661
BPY2 basic charge, Y-linked, 2 3.17484
WNT1 wingless-type MMTV integration site family, member 1 3.16962
DDIT3 DNA-damage-inducible transcript 3 3.16485
PECR peroxisomal trans-2-enoyl-CoA reductase 3.1623
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 3.15961
NPAS1 neuronal PAS domain protein 1 3.1575
ULK4 unc-51 like kinase 4 3.15583
TSSK1B testis-specific serine kinase 1B 3.15566
BBS4 Bardet-Biedl syndrome 4 3.15232
CALCA calcitonin-related polypeptide alpha 3.1499
NCKAP1 NCK-associated protein 1 3.14724
NBPF10 neuroblastoma breakpoint family, member 10 3.14646
DDAH1 dimethylarginine dimethylaminohydrolase 1 3.14265
NASP nuclear autoantigenic sperm protein (histone-binding) 3.14078
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 3.14043
ZNF271P zinc finger protein 271, pseudogene 3.13958
RRAD Ras-related associated with diabetes 3.13843
WWP1 WW domain containing E3 ubiquitin protein ligase 1 3.1346
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 3.13114
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 3.13019
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 3.12831
GRK5 G protein-coupled receptor kinase 5 3.12771
STK39 serine threonine kinase 39 3.12526
IFNA5 interferon, alpha 5 3.12416
GP6 glycoprotein VI (platelet) 3.12372
DYNLT1 dynein, light chain, Tctex-type 1 3.12241
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 3.12145
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 3.11904
ZNF44 zinc finger protein 44 3.11593
WNT11 wingless-type MMTV integration site family, member 11 3.11385
ANTXR1 anthrax toxin receptor 1 3.10802
GNG7 guanine nucleotide binding protein (G protein), gamma 7 3.10744
CLCA1 chloride channel accessory 1 3.10706
MINDY2 MINDY lysine 48 deubiquitinase 2 3.10435
SEPHS2 selenophosphate synthetase 2 3.10295
VENTXP1 VENT homeobox pseudogene 1 3.097
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 3.09031
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.08877
SHANK1 SH3 and multiple ankyrin repeat domains 1 3.087
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 3.08572
REPS2 RALBP1 associated Eps domain containing 2 3.08448
HCRTR1 hypocretin (orexin) receptor 1 3.08273
CA8 carbonic anhydrase VIII 3.08161
MUC13 mucin 13, cell surface associated 3.08139
TLR1 toll-like receptor 1 3.0773
ITM2C integral membrane protein 2C 3.07506
PPIG peptidylprolyl isomerase G (cyclophilin G) 3.07446
SACK1E scaffolding CK1 anchoring protein E 3.07339
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 3.06871
DEFA5 defensin, alpha 5, Paneth cell-specific 3.06774
FH fumarate hydratase 3.06753
MKKS McKusick-Kaufman syndrome 3.06742
ZBED1 zinc finger, BED-type containing 1 3.06688
SIRT3 sirtuin 3 3.06684
KRTAP1-3 keratin associated protein 1-3 3.06499
DPP6 dipeptidyl-peptidase 6 3.06481
SYBU syntabulin (syntaxin-interacting) 3.06337
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 3.05779
MAOA monoamine oxidase A 3.05407
FLII flightless I homolog (Drosophila) 3.04678
BZW1 basic leucine zipper and W2 domains 1 3.04619
UCK2 uridine-cytidine kinase 2 3.04546
RANBP17 RAN binding protein 17 3.04534
SEPTIN4 septin 4 3.0422
HNF1B HNF1 homeobox B 3.04045
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.03837
COX5A cytochrome c oxidase subunit Va 3.03738
ADGRB2 adhesion G protein-coupled receptor B2 3.0358
NSUN7 NOP2/Sun domain family, member 7 3.03576
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 3.03335
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 3.03259
IL6ST interleukin 6 signal transducer 3.03118
ZNF132 zinc finger protein 132 3.0295
UBE2G1 ubiquitin-conjugating enzyme E2G 1 3.02432
NOD2 nucleotide-binding oligomerization domain containing 2 3.02324
AMPD1 adenosine monophosphate deaminase 1 3.02267
SEC63 SEC63 homolog (S. cerevisiae) 3.02075
FOXC2 forkhead box C2 3.01659
GPR68 G protein-coupled receptor 68 3.01542
WAC WW domain containing adaptor with coiled-coil 3.0153
DAPK2 death-associated protein kinase 2 3.01463
CHPT1 choline phosphotransferase 1 3.01284
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 3.01273
NXPE4 neurexophilin and PC-esterase domain family, member 4 3.00719
MAPK7 mitogen-activated protein kinase 7 3.00419
LPAR1 lysophosphatidic acid receptor 1 3.00167

decreased expression

Symbol Name Standardized Value
GSTZ1 glutathione S-transferase zeta 1 -9.06482
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog -6.43711
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -6.163
GSTM5 glutathione S-transferase mu 5 -6.0161
PAN2 PAN2 poly(A) specific ribonuclease subunit -5.89791
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 -5.83924
DPH2 DPH2 homolog (S. cerevisiae) -5.65542
EIF2D eukaryotic translation initiation factor 2D -5.46963
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -5.3275
BCAS3 breast carcinoma amplified sequence 3 -5.2761
C2CD2 C2 calcium-dependent domain containing 2 -5.23764
TOR1A torsin family 1, member A (torsin A) -5.19191
RAD51B RAD51 paralog B -5.1861
EMC1 ER membrane protein complex subunit 1 -5.14413
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.12057
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) -5.11777
PHF11 PHD finger protein 11 -5.10413
STXBP1 syntaxin binding protein 1 -5.01923
SYCP2 synaptonemal complex protein 2 -5.00025
RTL8C retrotransposon Gag like 8C -4.98803
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -4.94189
RHOA ras homolog family member A -4.92565
PNMA1 paraneoplastic Ma antigen 1 -4.88363
TPK1 thiamin pyrophosphokinase 1 -4.87221
POFUT2 protein O-fucosyltransferase 2 -4.83364
TSPO2 translocator protein 2 -4.7889
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.7489
RBM19 RNA binding motif protein 19 -4.73737
CEP57 centrosomal protein 57kDa -4.71232
PLK1 polo-like kinase 1 -4.65959
LNPEP leucyl/cystinyl aminopeptidase -4.65669
RABL3 RAB, member of RAS oncogene family-like 3 -4.65561
CHEK1 checkpoint kinase 1 -4.63834
EPB41L5 erythrocyte membrane protein band 4.1 like 5 -4.63656
CUTA cutA divalent cation tolerance homolog (E. coli) -4.62126
NOS3 nitric oxide synthase 3 (endothelial cell) -4.61671
BATF basic leucine zipper transcription factor, ATF-like -4.61132
DUSP2 dual specificity phosphatase 2 -4.60596
EIF3F eukaryotic translation initiation factor 3, subunit F -4.59469
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 -4.56566
BUB1 BUB1 mitotic checkpoint serine/threonine kinase -4.55933
HACD1 3-hydroxyacyl-CoA dehydratase 1 -4.54034
FAHD2A fumarylacetoacetate hydrolase domain containing 2A -4.52208
GRM6 glutamate receptor, metabotropic 6 -4.51374
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -4.46831
USP20 ubiquitin specific peptidase 20 -4.44992
CER1 cerberus 1, DAN family BMP antagonist -4.40848
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -4.38798
NEIL3 nei endonuclease VIII-like 3 (E. coli) -4.38754
AURKA aurora kinase A -4.38731
CCT4 chaperonin containing TCP1, subunit 4 (delta) -4.38599
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.36387
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 -4.34779
ENDOD1 endonuclease domain containing 1 -4.33718
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -4.31304
WDR7 WD repeat domain 7 -4.31076
CA1 carbonic anhydrase I -4.29837
PLBD1 phospholipase B domain containing 1 -4.27
SPRR3 small proline-rich protein 3 -4.26783
HMBS hydroxymethylbilane synthase -4.25228
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -4.22452
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -4.21767
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 -4.19662
SPINT3 serine peptidase inhibitor, Kunitz type, 3 -4.19384
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -4.18198
BTN3A3 butyrophilin, subfamily 3, member A3 -4.16181
GPR45 G protein-coupled receptor 45 -4.15792
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -4.14449
MYL7 myosin, light chain 7, regulatory -4.13282
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) -4.12821
RNF185 ring finger protein 185 -4.11553
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 -4.11435
PTN pleiotrophin -4.11111
TPTE transmembrane phosphatase with tensin homology -4.10521
RALB v-ral simian leukemia viral oncogene homolog B -4.10194
RAP2B RAP2B, member of RAS oncogene family -4.08334
PFKL phosphofructokinase, liver -4.0784
ACSS3 acyl-CoA synthetase short-chain family member 3 -4.07598
CNR1 cannabinoid receptor 1 (brain) -4.01864
NUP88 nucleoporin 88kDa -4.01671
TJAP1 tight junction associated protein 1 (peripheral) -3.99637
POLQ polymerase (DNA directed), theta -3.99186
DCC DCC netrin 1 receptor -3.99175
DPYD dihydropyrimidine dehydrogenase -3.97387
GMPS guanine monphosphate synthase -3.97017
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -3.96187
AFTPH aftiphilin -3.95813
GSTCD glutathione S-transferase, C-terminal domain containing -3.95634
ALG3 ALG3, alpha-1,3- mannosyltransferase -3.95073
IGSF9B immunoglobulin superfamily, member 9B -3.94675
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.93292
TCEAL1 transcription elongation factor A (SII)-like 1 -3.92666
ZNF202 zinc finger protein 202 -3.92586
CD47 CD47 molecule -3.92095
KLK14 kallikrein-related peptidase 14 -3.91894
FMO4 flavin containing monooxygenase 4 -3.91857
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1 -3.91431
HLA-DMA major histocompatibility complex, class II, DM alpha -3.90639
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.90371
SELL selectin L -3.88643
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -3.86029
AKAP8 A kinase (PRKA) anchor protein 8 -3.8422
NKX3-1 NK3 homeobox 1 -3.84212
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -3.83486
RFC5 replication factor C (activator 1) 5, 36.5kDa -3.81935
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -3.80953
CRYBG3 beta-gamma crystallin domain containing 3 -3.80827
AUNIP aurora kinase A and ninein interacting protein -3.80663
FBXO7 F-box protein 7 -3.79579
TULP1 tubby like protein 1 -3.7935
OR12D3 olfactory receptor, family 12, subfamily D, member 3 -3.79104
GYG1 glycogenin 1 -3.78156
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.77012
DZIP3 DAZ interacting zinc finger protein 3 -3.76174
PIGL phosphatidylinositol glycan anchor biosynthesis, class L -3.75851
KLF12 Kruppel-like factor 12 -3.73752
SIX6 SIX homeobox 6 -3.73689
CRISP1 cysteine-rich secretory protein 1 -3.73279
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) -3.73199
ELP4 elongator acetyltransferase complex subunit 4 -3.72903
MMP12 matrix metallopeptidase 12 -3.72564
HLA-B major histocompatibility complex, class I, B -3.72451
SLC25A46 solute carrier family 25, member 46 -3.69299
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -3.69225
GBAP1 glucosidase, beta, acid pseudogene 1 -3.68873
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -3.66174
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -3.65919
MSH2 mutS homolog 2 -3.65455
MRAS muscle RAS oncogene homolog -3.65374
GLS glutaminase -3.64906
WDR6 WD repeat domain 6 -3.64885
DCX doublecortin -3.64047
BORA bora, aurora kinase A activator -3.63987
CAPRIN2 caprin family member 2 -3.62279
LRP2 low density lipoprotein receptor-related protein 2 -3.62088
ACBD4 acyl-CoA binding domain containing 4 -3.61973
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 -3.59597
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 -3.59367
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -3.57538
TRIM66 tripartite motif containing 66 -3.5667
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -3.56528
CEP72 centrosomal protein 72kDa -3.56501
PRKG2 protein kinase, cGMP-dependent, type II -3.56465
QRICH1 glutamine-rich 1 -3.56451
RANBP6 RAN binding protein 6 -3.56292
S100A6 S100 calcium binding protein A6 -3.56031
PTPRT protein tyrosine phosphatase, receptor type, T -3.55712
PTPN21 protein tyrosine phosphatase, non-receptor type 21 -3.55558
ELOVL5 ELOVL fatty acid elongase 5 -3.55489
CCN6 cellular communication network factor 6 -3.53092
LINC02249 long intergenic non-protein coding RNA 2249 -3.52549
NRBP1 nuclear receptor binding protein 1 -3.51468
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.51252
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -3.51068
INTS7 integrator complex subunit 7 -3.50966
TMSB10 thymosin beta 10 -3.50936
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -3.50648
ZCWPW1 zinc finger, CW type with PWWP domain 1 -3.49919
TPMT thiopurine S-methyltransferase -3.49546
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) -3.49131
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) -3.48942
SCN3A sodium channel, voltage gated, type III alpha subunit -3.48934
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 -3.48077
EPPIN epididymal peptidase inhibitor -3.48045
PARVA parvin, alpha -3.47371
ZSCAN31 zinc finger and SCAN domain containing 31 -3.47094
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa -3.47037
NR1D2 nuclear receptor subfamily 1, group D, member 2 -3.46929
ADRB2 adrenoceptor beta 2, surface -3.46641
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -3.4663
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -3.46542
ICAM3 intercellular adhesion molecule 3 -3.46418
PCDHA2 protocadherin alpha 2 -3.45987
ALAD aminolevulinate dehydratase -3.45956
ARHGAP24 Rho GTPase activating protein 24 -3.45799
SATB2 SATB homeobox 2 -3.44988
PCBP2 poly(rC) binding protein 2 -3.44078
SPON2 spondin 2, extracellular matrix protein -3.44017
HLTF helicase-like transcription factor -3.43176
TMUB2 transmembrane and ubiquitin-like domain containing 2 -3.42955
MBTPS1 membrane-bound transcription factor peptidase, site 1 -3.42546
ZNF76 zinc finger protein 76 -3.41408
SZRD1 SUZ RNA binding domain containing 1 -3.41033
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -3.40304
GMEB2 glucocorticoid modulatory element binding protein 2 -3.3983
MCM10 minichromosome maintenance complex component 10 -3.39725
OSBPL10 oxysterol binding protein-like 10 -3.3955
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -3.39378
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) -3.39094
MTMR2 myotubularin related protein 2 -3.38599
ANK1 ankyrin 1, erythrocytic -3.38131
C1ORF56 chromosome 1 open reading frame 56 -3.37366
DCTN2 dynactin 2 (p50) -3.37236
PCNT pericentrin -3.36776
PRKCI protein kinase C, iota -3.3651
CARTPT CART prepropeptide -3.36163
RBL2 retinoblastoma-like 2 -3.36121
ZNF239 zinc finger protein 239 -3.35938
LYST lysosomal trafficking regulator -3.3564
PSKH1 protein serine kinase H1 -3.35632
WNT5A wingless-type MMTV integration site family, member 5A -3.35475
RFC3 replication factor C (activator 1) 3, 38kDa -3.35136
CCNE1 cyclin E1 -3.34988
TMEM260 transmembrane protein 260 -3.34367
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -3.34164
LIFR leukemia inhibitory factor receptor alpha -3.34122
BABAM2 BRISC and BRCA1 A complex member 2 -3.33978
SLC35G2 solute carrier family 35, member G2 -3.33931
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta -3.33867
GLYAT glycine-N-acyltransferase -3.33836
FAM172A family with sequence similarity 172, member A -3.3358
UBQLN2 ubiquilin 2 -3.33321
NR6A1 nuclear receptor subfamily 6, group A, member 1 -3.33177
MCRS1 microspherule protein 1 -3.32909
TTK TTK protein kinase -3.32782
PRIM2 primase, DNA, polypeptide 2 (58kDa) -3.32557
NCAPH non-SMC condensin I complex, subunit H -3.32382
FRY furry homolog (Drosophila) -3.3236
SF3B3 splicing factor 3b, subunit 3, 130kDa -3.3139
CTNND2 catenin (cadherin-associated protein), delta 2 -3.31384
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -3.30474
GPR137 G protein-coupled receptor 137 -3.29911
ZNF140 zinc finger protein 140 -3.2987
SART3 squamous cell carcinoma antigen recognized by T cells 3 -3.29557
C9ORF40 chromosome 9 open reading frame 40 -3.2919
GON4L gon-4-like (C. elegans) -3.29004
PROZ protein Z, vitamin K-dependent plasma glycoprotein -3.28803
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) -3.28684
ENSA endosulfine alpha -3.28175
ZNF512B zinc finger protein 512B -3.27886
MAPK10 mitogen-activated protein kinase 10 -3.27157
FKBP6 FK506 binding protein 6, 36kDa -3.27047
DGKI diacylglycerol kinase, iota -3.26712
FAM110B family with sequence similarity 110, member B -3.26448
DVL3 dishevelled segment polarity protein 3 -3.26408
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 -3.26368
COLEC12 collectin sub-family member 12 -3.26238
GPATCH2 G patch domain containing 2 -3.26107
DENND2B DENN domain containing 2B -3.2605
CDK17 cyclin-dependent kinase 17 -3.25626
NCS1 neuronal calcium sensor 1 -3.25289
KIF18B kinesin family member 18B -3.24985
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 -3.24768
AAK1 AP2 associated kinase 1 -3.24177
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain -3.23926
VIM vimentin -3.23879
TMPRSS11E transmembrane protease, serine 11E -3.23811
ALG6 ALG6, alpha-1,3-glucosyltransferase -3.23757
CDC42 cell division cycle 42 -3.23152
NXPH3 neurexophilin 3 -3.2292
PTPRG protein tyrosine phosphatase, receptor type, G -3.22895
NISCH nischarin -3.22763
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) -3.22514
GFOD1 glucose-fructose oxidoreductase domain containing 1 -3.2249
LYN LYN proto-oncogene, Src family tyrosine kinase -3.22262
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa -3.21913
PARP3 poly (ADP-ribose) polymerase family, member 3 -3.21747
ENTR1 endosome associated trafficking regulator 1 -3.2155
HLA-F major histocompatibility complex, class I, F -3.20836
THOP1 thimet oligopeptidase 1 -3.20783
MSN moesin -3.19941
STK32B serine/threonine kinase 32B -3.19697
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.1965
FMR1 fragile X mental retardation 1 -3.19466
CMTR1 cap methyltransferase 1 -3.1925
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -3.19013
GRK6 G protein-coupled receptor kinase 6 -3.1888
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -3.18789
CCHCR1 coiled-coil alpha-helical rod protein 1 -3.18655
IRF6 interferon regulatory factor 6 -3.18641
NXT2 nuclear transport factor 2-like export factor 2 -3.1864
JADE2 jade family PHD finger 2 -3.18555
ZNF507 zinc finger protein 507 -3.1844
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.17536
CDC7 cell division cycle 7 -3.17347
RNF123 ring finger protein 123 -3.17063
TMPO thymopoietin -3.16697
ZNF266 zinc finger protein 266 -3.16686
OARD1 O-acyl-ADP-ribose deacylase 1 -3.16627
KPNA1 karyopherin alpha 1 (importin alpha 5) -3.15551
ADCY7 adenylate cyclase 7 -3.15523
GTDC1 glycosyltransferase-like domain containing 1 -3.15427
USP4 ubiquitin specific peptidase 4 (proto-oncogene) -3.15373
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -3.1534
A4GNT alpha-1,4-N-acetylglucosaminyltransferase -3.14656
LRP12 low density lipoprotein receptor-related protein 12 -3.1455
TLN2 talin 2 -3.14225
ATP7B ATPase, Cu++ transporting, beta polypeptide -3.13697
MATN2 matrilin 2 -3.13403
MPP1 membrane protein, palmitoylated 1, 55kDa -3.1256
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) -3.12227
KIF14 kinesin family member 14 -3.11513
TMEM161A transmembrane protein 161A -3.11189
REXO2 RNA exonuclease 2 -3.11096
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 -3.10702
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -3.10449
DCAF17 DDB1 and CUL4 associated factor 17 -3.10104
METTL1 methyltransferase like 1 -3.1002
RBMX2 RNA binding motif protein, X-linked 2 -3.10013
R3HDM2 R3H domain containing 2 -3.09949
ACD adrenocortical dysplasia homolog (mouse) -3.09879
RECQL5 RecQ protein-like 5 -3.09865
KIF18A kinesin family member 18A -3.09782
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -3.09767
CGREF1 cell growth regulator with EF-hand domain 1 -3.09728
LOC155060 AI894139 pseudogene -3.0964
TMEM53 transmembrane protein 53 -3.09416
FGR FGR proto-oncogene, Src family tyrosine kinase -3.09294
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.09151
SLC39A9 solute carrier family 39, member 9 -3.09043
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -3.09042
RAP2C RAP2C, member of RAS oncogene family -3.08832
CUZD1 CUB and zona pellucida-like domains 1 -3.08794
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) -3.08767
EDDM3A epididymal protein 3A -3.08733
TIAM2 T-cell lymphoma invasion and metastasis 2 -3.08522
RBM14 RNA binding motif protein 14 -3.0846
RTL8A retrotransposon Gag like 8A -3.08415
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -3.08274
ESD esterase D -3.08149
EXOC2 exocyst complex component 2 -3.07947
ITM2B integral membrane protein 2B -3.07842
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -3.07734
CLDN6 claudin 6 -3.07531
TCF20 transcription factor 20 (AR1) -3.07057
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) -3.0676
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4 -3.06677
VGLL4 vestigial-like family member 4 -3.06426
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B -3.05938
ZPBP zona pellucida binding protein -3.05776
RBM8A RNA binding motif protein 8A -3.05485
SERGEF secretion regulating guanine nucleotide exchange factor -3.05329
TTLL5 tubulin tyrosine ligase-like family member 5 -3.05321
GTPBP8 GTP-binding protein 8 (putative) -3.05077
UMPS uridine monophosphate synthetase -3.04729
CD36 CD36 molecule (thrombospondin receptor) -3.04652
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 -3.04624
DIDO1 death inducer-obliterator 1 -3.04419
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -3.04168
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B -3.04004
CADM3 cell adhesion molecule 3 -3.033
MAGEH1 melanoma antigen family H1 -3.03038
LDHA lactate dehydrogenase A -3.02457
DUSP5 dual specificity phosphatase 5 -3.02026
NGLY1 N-glycanase 1 -3.01522
NPR3 natriuretic peptide receptor 3 -3.01366
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 -3.01258
PGAP2 post-GPI attachment to proteins 2 -3.00501
PRPF39 pre-mRNA processing factor 39 -3.00285