nr4a2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description nuclear receptor subfamily 4, group A, member 2|This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 4929)
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Genes

13 genes co-occuring with the biological term nr4a2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BDNF brain-derived neurotrophic factor
CXCL8 chemokine (C-X-C motif) ligand 8
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
EDN1 endothelin 1
GAST gastrin
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PROM1 prominin 1
THBS1 thrombospondin 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZFP36L1 ZFP36 ring finger protein-like 1