nuclear envelope Gene Set

Dataset LOCATE Curated Protein Localization Annotations
Category proteomics
Type cellular component
Description The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). (Gene Ontology, GO_0005635)
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90 proteins localized to the nuclear envelope cellular component in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset.

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AIF1L allograft inflammatory factor 1-like
AKAP6 A kinase (PRKA) anchor protein 6
AKT1S1 AKT1 substrate 1 (proline-rich)
ANLN anillin, actin binding protein
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
BIK BCL2-interacting killer (apoptosis-inducing)
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
CANX calnexin
CTSB cathepsin B
DDX19A DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DNAAF5 dynein, axonemal, assembly factor 5
DNAJC30 DnaJ (Hsp40) homolog, subfamily C, member 30
DNASE1 deoxyribonuclease I
EFTUD2 elongation factor Tu GTP binding domain containing 2
EMC2 ER membrane protein complex subunit 2
EMD emerin
FAM156A family with sequence similarity 156, member A
FAR1 fatty acyl CoA reductase 1
FYTTD1 forty-two-three domain containing 1
GCOM1 GRINL1A complex locus 1
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae)
GLE1 GLE1 RNA export mediator
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
HAX1 HCLS1 associated protein X-1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12
IFI27 interferon, alpha-inducible protein 27
IL4I1 interleukin 4 induced 1
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
LBR lamin B receptor
LMNA lamin A/C
LMNB1 lamin B1
MGST1 microsomal glutathione S-transferase 1
MTMR6 myotubularin related protein 6
MYADML myeloid-associated differentiation marker-like (pseudogene)
NARF nuclear prelamin A recognition factor
NDC1 NDC1 transmembrane nucleoporin
NUP153 nucleoporin 153kDa
NUP188 nucleoporin 188kDa
NUP210 nucleoporin 210kDa
NUP35 nucleoporin 35kDa
NUP37 nucleoporin 37kDa
NUP62 nucleoporin 62kDa
NUP88 nucleoporin 88kDa
NUP93 nucleoporin 93kDa
NUPL2 nucleoporin like 2
NXF1 nuclear RNA export factor 1
NXF2 nuclear RNA export factor 2
PNKD paroxysmal nonkinesigenic dyskinesia
POLR2M polymerase (RNA) II (DNA directed) polypeptide M
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPAPDC3 phosphatidic acid phosphatase type 2 domain containing 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRICKLE1 prickle homolog 1 (Drosophila)
PRPH peripherin
PSEN2 presenilin 2
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
QARS glutaminyl-tRNA synthetase
RACGAP1 Rac GTPase activating protein 1
RANBP2 RAN binding protein 2
RPL8 ribosomal protein L8
RUSC1 RUN and SH3 domain containing 1
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCARA3 scavenger receptor class A, member 3
SEC13 SEC13 homolog (S. cerevisiae)
SFPQ splicing factor proline/glutamine-rich
SHISA5 shisa family member 5
SIGMAR1 sigma non-opioid intracellular receptor 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPCS2 signal peptidase complex subunit 2 homolog (S. cerevisiae)
SPCS2P4 signal peptidase complex subunit 2 homolog (S. cerevisiae) pseudogene 4
SREBF1 sterol regulatory element binding transcription factor 1
SRPR signal recognition particle receptor (docking protein)
SUMO2 small ubiquitin-like modifier 2
SUN1 Sad1 and UNC84 domain containing 1
SUN2 Sad1 and UNC84 domain containing 2
SYNE2 spectrin repeat containing, nuclear envelope 2
TMEM43 transmembrane protein 43
TMPO thymopoietin
TNPO1 transportin 1
TOR1A torsin family 1, member A (torsin A)
TPO thyroid peroxidase
TRAF3 TNF receptor-associated factor 3
TTLL5 tubulin tyrosine ligase-like family member 5