nucleolus Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. (Gene Ontology, GO_0005730)
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Genes

92 genes co-occuring with the biological term nucleolus in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APP amyloid beta (A4) precursor protein
APTX aprataxin
BRCA1 breast cancer 1, early onset
C6ORF89 chromosome 6 open reading frame 89
CAPG capping protein (actin filament), gelsolin-like
CCDC137 coiled-coil domain containing 137
CDC14B cell division cycle 14B
CDC73 cell division cycle 73
CDKN2A cyclin-dependent kinase inhibitor 2A
CHD4 chromodomain helicase DNA binding protein 4
CHD7 chromodomain helicase DNA binding protein 7
CIAPIN1 cytokine induced apoptosis inhibitor 1
COIL coilin
CRBN cereblon
CTCF CCCTC-binding factor (zinc finger protein)
DGCR8 DGCR8 microprocessor complex subunit
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
EGR1 early growth response 1
ERCC8 excision repair cross-complementation group 8
ESRRA estrogen-related receptor alpha
FAM9A family with sequence similarity 9, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGF2 fibroblast growth factor 2 (basic)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNL1 guanine nucleotide binding protein-like 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HOTS H19 Opposite Tumor Suppressor
JUN jun proto-oncogene
JUP junction plakoglobin
KL klotho
KRT18 keratin 18, type I
LMNB1 lamin B1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MCRS1 microspherule protein 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAT10 N-acetyltransferase 10 (GCN5-related)
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NF2 neurofibromin 2 (merlin)
NOAZFP nucleolar atypical zinc finger
NOM1 nucleolar protein with MIF4G domain 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUCLEOLIN nucleolin multifunctional protein
PA2G4 proliferation-associated 2G4, 38kDa
PARK7 parkinson protein 7
PARP1 poly (ADP-ribose) polymerase 1
PER2 period circadian clock 2
PHF6 PHD finger protein 6
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PML promyelocytic leukemia
RASL10A RAS-like, family 10, member A
RBM28 RNA binding motif protein 28
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPL11 ribosomal protein L11
RPL5 ribosomal protein L5
RPS3 ribosomal protein S3
RPSA ribosomal protein SA
RPTOR regulatory associated protein of MTOR, complex 1
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERBP1 SERPINE1 mRNA binding protein 1
SIRT6 sirtuin 6
SP100 SP100 nuclear antigen
SPATS2L spermatogenesis associated, serine-rich 2-like
SUMO1 small ubiquitin-like modifier 1
TBPL1 TBP-like 1
TERF2 telomeric repeat binding factor 2
TOP1 topoisomerase (DNA) I
TP53 tumor protein p53
TP53INP2 tumor protein p53 inducible nuclear protein 2
TRIM27 tripartite motif containing 27
TUBG1 tubulin, gamma 1
TUBGCP2 tubulin, gamma complex associated protein 2
TUBGCP3 tubulin, gamma complex associated protein 3
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast)
WRN Werner syndrome, RecQ helicase-like
XPO1 exportin 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
XRN2 5'-3' exoribonuclease 2