nurd complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins. (Gene Ontology, GO_0016581)
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Genes

190 proteins co-occuring with the nurd complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CHD4 chromodomain helicase DNA binding protein 4 2.38696
MTA1 metastasis associated 1 2.27675
MTA2 metastasis associated 1 family, member 2 2.13768
MTA3 metastasis associated 1 family, member 3 1.84156
HDAC1 histone deacetylase 1 1.65092
ZFPM1 zinc finger protein, FOG family member 1 1.54687
RBBP4 retinoblastoma binding protein 4 1.53105
HDAC2 histone deacetylase 2 1.47344
CHD3 chromodomain helicase DNA binding protein 3 1.38239
GATAD2B GATA zinc finger domain containing 2B 1.35923
HDAC9 histone deacetylase 9 1.26604
GATAD2A GATA zinc finger domain containing 2A 1.234
SIN3A SIN3 transcription regulator family member A 1.2288
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 1.1644
MBD3L1 methyl-CpG binding domain protein 3-like 1 1.16338
RCOR1 REST corepressor 1 1.14801
MBD3 methyl-CpG binding domain protein 3 1.12501
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 1.0258
HIC1 hypermethylated in cancer 1 1.01982
MBD3L2 methyl-CpG binding domain protein 3-like 2 1.01933
SALL1 spalt-like transcription factor 1 1.00547
SETDB1 SET domain, bifurcated 1 1.00399
KDM1A lysine (K)-specific demethylase 1A 1.00153
PCCA propionyl CoA carboxylase, alpha polypeptide 0.994652
ZNF521 zinc finger protein 521 0.863528
ZFHX4 zinc finger homeobox 4 0.863528
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.862609
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.80523
EBF1 early B-cell factor 1 0.801104
RBBP7 retinoblastoma binding protein 7 0.771819
ZGPAT zinc finger, CCCH-type with G patch domain 0.764072
ZNF827 zinc finger protein 827 0.754983
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.754983
H3F3A H3 histone, family 3A 0.750904
H3F3B H3 histone, family 3B (H3.3B) 0.750904
PHF6 PHD finger protein 6 0.678978
ZFPM2 zinc finger protein, FOG family member 2 0.671593
FAM64A family with sequence similarity 64, member A 0.6638
GFI1B growth factor independent 1B transcription repressor 0.662503
NCOR1 nuclear receptor corepressor 1 0.655172
FOXK1 forkhead box K1 0.643144
MBD2 methyl-CpG binding domain protein 2 0.638005
NANOG Nanog homeobox 0.628613
BCOR BCL6 corepressor 0.622229
PIAS1 protein inhibitor of activated STAT, 1 0.607395
TRIM27 tripartite motif containing 27 0.60444
GIGYF2 GRB10 interacting GYF protein 2 0.603596
CCL14 chemokine (C-C motif) ligand 14 0.599802
CARM1 coactivator-associated arginine methyltransferase 1 0.595173
KLF1 Kruppel-like factor 1 (erythroid) 0.588875
FOXP4 forkhead box P4 0.58678
HDAC3 histone deacetylase 3 0.586361
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.568832
PRMT5 protein arginine methyltransferase 5 0.563432
FOXK2 forkhead box K2 0.558871
FOXP1 forkhead box P1 0.553905
PIAS2 protein inhibitor of activated STAT, 2 0.539472
ACTL6A actin-like 6A 0.532488
E2F7 E2F transcription factor 7 0.523885
TBX18 T-box 18 0.523885
EOMES eomesodermin 0.519798
MYB v-myb avian myeloblastosis viral oncogene homolog 0.517348
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.510418
EGLN2 egl-9 family hypoxia-inducible factor 2 0.509197
TBX20 T-box 20 0.50879
DNAH8 dynein, axonemal, heavy chain 8 0.508383
ESR1 estrogen receptor 1 0.498636
ATOH1 atonal homolog 1 (Drosophila) 0.488923
L3MBTL2 l(3)mbt-like 2 (Drosophila) 0.488923
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.487711
SALL4 spalt-like transcription factor 4 0.486096
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) 0.482467
PIAS3 protein inhibitor of activated STAT, 3 0.479647
TRIM28 tripartite motif containing 28 0.470807
LECT2 leukocyte cell-derived chemotaxin 2 0.459602
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.456012
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.449245
RNF168 ring finger protein 168, E3 ubiquitin protein ligase 0.449245
MECP2 methyl CpG binding protein 2 0.449245
PRMT7 protein arginine methyltransferase 7 0.448848
ZNF217 zinc finger protein 217 0.443689
LMO2 LIM domain only 2 (rhombotin-like 1) 0.439333
TRIM24 tripartite motif containing 24 0.433407
ZNF423 zinc finger protein 423 0.430253
EGR2 early growth response 2 0.427497
SAE1 SUMO1 activating enzyme subunit 1 0.425924
TP53 tumor protein p53 0.42396
ARID1A AT rich interactive domain 1A (SWI-like) 0.421604
PHF21A PHD finger protein 21A 0.420428
EGR1 early growth response 1 0.418468
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.415728
PHF19 PHD finger protein 19 0.410259
RPL26L1 ribosomal protein L26-like 1 0.409869
ELF5 E74-like factor 5 (ets domain transcription factor) 0.399363
TET1 tet methylcytosine dioxygenase 1 0.397811
KDM3A lysine (K)-specific demethylase 3A 0.396648
RNF8 ring finger protein 8, E3 ubiquitin protein ligase 0.386979
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.38428
MECOM MDS1 and EVI1 complex locus 0.378122
TAL1 T-cell acute lymphocytic leukemia 1 0.375434
MYCBP MYC binding protein 0.371599
KLF10 Kruppel-like factor 10 0.368153
GBX2 gastrulation brain homeobox 2 0.360133
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.355183
CTBP1 C-terminal binding protein 1 0.352142
SETD1B SET domain containing 1B 0.346071
CDX2 caudal type homeobox 2 0.345692
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.343042
BCL6 B-cell CLL/lymphoma 6 0.342664
WDR77 WD repeat domain 77 0.336996
ZBTB7A zinc finger and BTB domain containing 7A 0.335487
SAP18 Sin3A-associated protein, 18kDa 0.33511
VPRBP Vpr (HIV-1) binding protein 0.332848
KDM5B lysine (K)-specific demethylase 5B 0.329084
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 0.326078
SIN3B SIN3 transcription regulator family member B 0.318953
HNMT histamine N-methyltransferase 0.310732
HIST2H4B histone cluster 2, H4b 0.307377
HIST1H4E histone cluster 1, H4e 0.307377
HIST1H4C histone cluster 1, H4c 0.307377
HIST1H4H histone cluster 1, H4h 0.307377
HIST1H4I histone cluster 1, H4i 0.307377
HIST1H4B histone cluster 1, H4b 0.307377
HIST1H4J histone cluster 1, H4j 0.307377
HIST1H4K histone cluster 1, H4k 0.307377
HIST1H4D histone cluster 1, H4d 0.307377
HIST1H4A histone cluster 1, H4a 0.307377
HIST1H4L histone cluster 1, H4l 0.307004
HIST2H4A histone cluster 2, H4a 0.307004
HIST1H4F histone cluster 1, H4f 0.307004
HIST4H4 histone cluster 4, H4 0.307004
HDAC5 histone deacetylase 5 0.305143
RUVBL1 RuvB-like AAA ATPase 1 0.304027
SAP30 Sin3A-associated protein, 30kDa 0.303655
ZNF222 zinc finger protein 222 0.302912
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.301054
KDM5A lysine (K)-specific demethylase 5A 0.294748
MCRS1 microspherule protein 1 0.293637
CIDEB cell death-inducing DFFA-like effector b 0.292527
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.291417
RPL26 ribosomal protein L26 0.291047
HBG2 hemoglobin, gamma G 0.290678
TRIM10 tripartite motif containing 10 0.289569
ARID1B AT rich interactive domain 1B (SWI1-like) 0.287721
TAF1L TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like 0.287352
TRIM26 tripartite motif containing 26 0.284401
PAX5 paired box 5 0.281085
AKR1C4 aldo-keto reductase family 1, member C4 0.281085
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.280716
TRIM15 tripartite motif containing 15 0.274468
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.274468
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.272267
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.271533
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.2708
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.269701
TTF1 transcription termination factor, RNA polymerase I 0.268237
GATA2 GATA binding protein 2 0.26166
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.256197
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.249664
UBA2 ubiquitin-like modifier activating enzyme 2 0.249302
HARS histidyl-tRNA synthetase 0.248216
SETD1A SET domain containing 1A 0.240636
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.236683
HDAC4 histone deacetylase 4 0.230958
FOXH1 forkhead box H1 0.230601
SIX2 SIX homeobox 2 0.228108
RAD21 RAD21 homolog (S. pombe) 0.226686
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.225622
LDB1 LIM domain binding 1 0.223143
MAT2A methionine adenosyltransferase II, alpha 0.214714
RNF2 ring finger protein 2 0.214017
KAT7 K(lysine) acetyltransferase 7 0.212627
TIPIN TIMELESS interacting protein 0.199325
MORF4 mortality factor 4 (pseudogene) 0.195681
EGLN3 egl-9 family hypoxia-inducible factor 3 0.195681
RSPO1 R-spondin 1 0.190175
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.179459
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.179167
TDG thymine-DNA glycosylase 0.176587
CHD1L chromodomain helicase DNA binding protein 1-like 0.173273
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.171673
TCF12 transcription factor 12 0.167366
EWSR1 EWS RNA-binding protein 1 0.165463
THBS4 thrombospondin 4 0.165463
EGR3 early growth response 3 0.16298
PAX2 paired box 2 0.16233
WIPF2 WAS/WASL interacting protein family, member 2 0.160456
PLAUR plasminogen activator, urokinase receptor 0.159658
PELP1 proline, glutamate and leucine rich protein 1 0.157397
SENP1 SUMO1/sentrin specific peptidase 1 0.157397