nutrition disease Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An acquired metabolic disease that is characterized by an insufficient intake of food or of certain nutrients, by an inability of the body to absorb and use nutrients, or by overconsumption of certain foods. (Human Disease Ontology, DOID_374)
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Genes

144 genes associated with the disease nutrition disease in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
GC group-specific component (vitamin D binding protein) 2.63296
CETP cholesteryl ester transfer protein, plasma 2.18152
COBLL1 cordon-bleu WH2 repeat protein-like 1 1.86862
RSPO3 R-spondin 3 1.82071
ZPR1 ZPR1 zinc finger 1.79105
NADSYN1 NAD synthetase 1 1.64122
VEGFA vascular endothelial growth factor A 1.61356
G6PC2 glucose-6-phosphatase, catalytic, 2 1.59919
SPC25 SPC25, NDC80 kinetochore complex component 1.59919
TBX15 T-box 15 1.55692
NFE2L3 nuclear factor, erythroid 2-like 3 1.55524
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 1.54448
LIPC lipase, hepatic 1.53147
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 1.36401
GCKR glucokinase (hexokinase 4) regulator 1.34736
DNM3 dynamin 3 1.24299
PIGC phosphatidylinositol glycan anchor biosynthesis, class C 1.24299
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 1.22898
LIN7C lin-7 homolog C (C. elegans) 1.20753
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 1.14929
TF transferrin 1.14929
GNPDA2 glucosamine-6-phosphate deaminase 2 1.13588
MTNR1B melatonin receptor 1B 1.11998
HOXC13 homeobox C13 1.1139
HFE hemochromatosis 1.06123
LPL lipoprotein lipase 1.02486
GCK glucokinase (hexokinase 4) 0.923046
MLXIPL MLX interacting protein-like 0.790827
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) 0.790827
ZNRF3 zinc and ring finger 3 0.774217
SH2B1 SH2B adaptor protein 1 0.752991
TMPRSS6 transmembrane protease, serine 6 0.728541
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.728541
APOB apolipoprotein B 0.724323
EDC4 enhancer of mRNA decapping 4 0.69843
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.682635
NISCH nischarin 0.670996
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.65413
BUD13 BUD13 homolog (S. cerevisiae) 0.641775
NR1H3 nuclear receptor subfamily 1, group H, member 3 0.63207
OLFM4 olfactomedin 4 0.602429
FTO fat mass and obesity associated 0.602429
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.602429
HOXB5 homeobox B5 0.572184
MTCH2 mitochondrial carrier 2 0.561725
PAX5 paired box 5 0.5306
MSRA methionine sulfoxide reductase A 0.5306
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.52461
MICB MHC class I polypeptide-related sequence B 0.486425
KCTD15 potassium channel tetramerization domain containing 15 0.486425
RPS17P5 ribosomal protein S17 pseudogene 5 0.464771
SLC30A10 solute carrier family 30, member 10 0.464771
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.449873
NCAM2 neural cell adhesion molecule 2 0.449873
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.449873
MRPS22 mitochondrial ribosomal protein S22 0.438544
NRXN3 neurexin 3 0.438544
NEGR1 neuronal growth regulator 1 0.429338
SPRY2 sprouty homolog 2 (Drosophila) 0.4215
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.414708
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.403461
INHBB inhibin, beta B 0.368757
GDAP1 ganglioside induced differentiation associated protein 1 0.368757
CHD2 chromodomain helicase DNA binding protein 2 0.368757
TBCE tubulin folding cofactor E 0.345945
NPC1 Niemann-Pick disease, type C1 0.345945
ARG1 arginase 1 0.345945
SOX6 SRY (sex determining region Y)-box 6 0.327313
BCDIN3D BCDIN3 domain containing 0.327313
FADS2 fatty acid desaturase 2 0.327313
FADS1 fatty acid desaturase 1 0.297866
TMEM258 transmembrane protein 258 0.297866
LHFPL3 lipoma HMGIC fusion partner-like 3 0.285417
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.285417
PCDH9 protocadherin 9 0.285417
TTC28 tetratricopeptide repeat domain 28 0.285417
WWOX WW domain containing oxidoreductase 0.274608
ZNF248 zinc finger protein 248 0.264872
ALPK1 alpha-kinase 1 0.256228
SV2C synaptic vesicle glycoprotein 2C 0.256228
CMYA5 cardiomyopathy associated 5 0.256228
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.256228
EML6 echinoderm microtubule associated protein like 6 0.256228
ENG endoglin 0.256228
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.256228
STK33 serine/threonine kinase 33 0.256228
FAIM2 Fas apoptotic inhibitory molecule 2 0.197766
MAP1A microtubule-associated protein 1A 0.197766
CDH12 cadherin 12, type 2 (N-cadherin 2) 0.197766
DARS aspartyl-tRNA synthetase 0.197766
SFRP2 secreted frizzled-related protein 2 0.197766
CAMK1G calcium/calmodulin-dependent protein kinase IG 0.197766
EIF4E3 eukaryotic translation initiation factor 4E family member 3 0.15771
EXOC4 exocyst complex component 4 0.15771
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.15771
HOXB1 homeobox B1 0.15771
SAMD13 sterile alpha motif domain containing 13 0.15771
STOML3 stomatin (EPB72)-like 3 0.15771
LCT lactase 0.126165
MDFIC MyoD family inhibitor domain containing 0.126165
ANO3 anoctamin 3 0.126165
MEX3B mex-3 RNA binding family member B 0.126165
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.126165
PKP1 plakophilin 1 0.126165
RARB retinoic acid receptor, beta 0.126165
COL21A1 collagen, type XXI, alpha 1 0.126165
ANKDD1B ankyrin repeat and death domain containing 1B 0.126165
FBN2 fibrillin 2 0.126165
APOC1 apolipoprotein C-I 0.126165
PFKP phosphofructokinase, platelet 0.100789
RGS6 regulator of G-protein signaling 6 0.100789
MACROD2 MACRO domain containing 2 0.100789
DIRAS2 DIRAS family, GTP-binding RAS-like 2 0.100789
KDM4C lysine (K)-specific demethylase 4C 0.100789
PALD1 phosphatase domain containing, paladin 1 0.100789
RFTN1 raftlin, lipid raft linker 1 0.100789
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.100789
OVCH2 ovochymase 2 (gene/pseudogene) 0.100789
THEMIS thymocyte selection associated 0.080593
ARHGAP12 Rho GTPase activating protein 12 0.080593
HDAC4 histone deacetylase 4 0.080593
MLN motilin 0.080593
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 0.080593
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.080593
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.080593
FAT1 FAT atypical cadherin 1 0.064973
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.064973
KCTD8 potassium channel tetramerization domain containing 8 0.064973
LIPA lipase A, lysosomal acid, cholesterol esterase 0.064973
TRUB2 TruB pseudouridine (psi) synthase family member 2 0.064973
MC4R melanocortin 4 receptor 0.064973
IFITM8P interferon induced transmembrane protein 8 pseudogene 0.064973
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.064973
POC5 POC5 centriolar protein 0.052255
CYB5R2 cytochrome b5 reductase 2 0.052255
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.052255
INO80D INO80 complex subunit D 0.052255
NRXN1 neurexin 1 0.052255
C9ORF84 chromosome 9 open reading frame 84 0.052255
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.052255
CRTAC1 cartilage acidic protein 1 0.043246
SACK1B scaffolding CK1 anchoring protein B 0.043246
C8ORF37 chromosome 8 open reading frame 37 0.043246
HOXB3 homeobox B3 0.043246