nystatin-2500 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the nystatin-2500 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADCK2 aarF domain containing kinase 2
AGRN agrin
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ANXA2P3 annexin A2 pseudogene 3
AQP9 aquaporin 9
ARHGAP44 Rho GTPase activating protein 44
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
C21ORF2 chromosome 21 open reading frame 2
CABP2 calcium binding protein 2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCL4 chemokine (C-C motif) ligand 4
CD70 CD70 molecule
CDK20 cyclin-dependent kinase 20
CDO1 cysteine dioxygenase type 1
CFAP45 cilia and flagella associated protein 45
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIITA class II, major histocompatibility complex, transactivator
CLEC4E C-type lectin domain family 4, member E
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRMP1 collapsin response mediator protein 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTSZ cathepsin Z
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
DCT dopachrome tautomerase
DHRS12 dehydrogenase/reductase (SDR family) member 12
EMP1 epithelial membrane protein 1
EPHA4 EPH receptor A4
FAM215A family with sequence similarity 215, member A (non-protein coding)
FGFBP1 fibroblast growth factor binding protein 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIST1H3G histone cluster 1, H3g
HOXA1 homeobox A1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL1B interleukin 1, beta
INO80B INO80 complex subunit B
JAK3 Janus kinase 3
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLF3 Kruppel-like factor 3 (basic)
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LIMK1 LIM domain kinase 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MCM3AP minichromosome maintenance complex component 3 associated protein
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP19 matrix metallopeptidase 19
MMP9 matrix metallopeptidase 9
MOBP myelin-associated oligodendrocyte basic protein
MRPS12 mitochondrial ribosomal protein S12
MXD4 MAX dimerization protein 4
NCKAP1L NCK-associated protein 1-like
NIPAL2 NIPA-like domain containing 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP88 nucleoporin 88kDa
OMG oligodendrocyte myelin glycoprotein
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PDZK1IP1 PDZK1 interacting protein 1
PIP prolactin-induced protein
RAB11B RAB11B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASL11B RAS-like, family 11, member B
RELN reelin
REPS1 RALBP1 associated Eps domain containing 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
ROM1 retinal outer segment membrane protein 1
RXRB retinoid X receptor, beta
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC35F5 solute carrier family 35, member F5
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS2 sorbin and SH3 domain containing 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH3 slingshot protein phosphatase 3
STARD13 StAR-related lipid transfer (START) domain containing 13
TET3 tet methylcytosine dioxygenase 3
TIMP2 TIMP metallopeptidase inhibitor 2
TK2 thymidine kinase 2, mitochondrial
TONSL tonsoku-like, DNA repair protein
TRBC1 T cell receptor beta constant 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WAPAL wings apart-like homolog (Drosophila)
ZNF749 zinc finger protein 749
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AEN apoptosis enhancing nuclease
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHDC1 AT hook, DNA binding motif, containing 1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AIRE autoimmune regulator
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B9D2 B9 protein domain 2
BCAS3 breast carcinoma amplified sequence 3
BTBD2 BTB (POZ) domain containing 2
CCDC106 coiled-coil domain containing 106
CCDC85C coiled-coil domain containing 85C
CD34 CD34 molecule
CDK3 cyclin-dependent kinase 3
CELP carboxyl ester lipase pseudogene
COQ6 coenzyme Q6 monooxygenase
CROT carnitine O-octanoyltransferase
DDN dendrin
DGKG diacylglycerol kinase, gamma 90kDa
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOK5 docking protein 5
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FES FES proto-oncogene, tyrosine kinase
FGL2 fibrinogen-like 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXO4 forkhead box O4
GAREM GRB2 associated, regulator of MAPK1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN7 gem (nuclear organelle) associated protein 7
GPR19 G protein-coupled receptor 19
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
GRPR gastrin-releasing peptide receptor
HSPB8 heat shock 22kDa protein 8
IDI2-AS1 IDI2 antisense RNA 1
IFI6 interferon, alpha-inducible protein 6
IL24 interleukin 24
INO80D INO80 complex subunit D
IQCG IQ motif containing G
IRF7 interferon regulatory factor 7
JMJD4 jumonji domain containing 4
KIAA1107 KIAA1107
KIFC3 kinesin family member C3
LIN7B lin-7 homolog B (C. elegans)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAGIX MAGI family member, X-linked
MAK male germ cell-associated kinase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEGF8 multiple EGF-like-domains 8
MX2 MX dynamin-like GTPase 2
NOD2 nucleotide-binding oligomerization domain containing 2
NSUN6 NOP2/Sun domain family, member 6
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PFN2 profilin 2
PLCD1 phospholipase C, delta 1
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PQLC2 PQ loop repeat containing 2
PROCR protein C receptor, endothelial
PSKH1 protein serine kinase H1
PYGB phosphorylase, glycogen; brain
RAB13 RAB13, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
SARS2 seryl-tRNA synthetase 2, mitochondrial
SENP7 SUMO1/sentrin specific peptidase 7
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC12A9 solute carrier family 12, member 9
SNX15 sorting nexin 15
SNX29P2 sorting nexin 29 pseudogene 2
SOX12 SRY (sex determining region Y)-box 12
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
THOP1 thimet oligopeptidase 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TM7SF2 transmembrane 7 superfamily member 2
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN13 tetraspanin 13
TSPAN2 tetraspanin 2
TTC26 tetratricopeptide repeat domain 26
UNC119 unc-119 homolog (C. elegans)
UPK3A uroplakin 3A
VASH1 vasohibin 1
VSIG10 V-set and immunoglobulin domain containing 10
WDR62 WD repeat domain 62
XDH xanthine dehydrogenase
XYLT2 xylosyltransferase II
ZBTB16 zinc finger and BTB domain containing 16
ZNF276 zinc finger protein 276
ZNF528 zinc finger protein 528