nystatin-4223 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the nystatin-4223 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADAM11 ADAM metallopeptidase domain 11
ADAM7 ADAM metallopeptidase domain 7
ADGRB2 adhesion G protein-coupled receptor B2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANP32A-IT1 ANP32A intronic transcript 1
APOA1 apolipoprotein A-I
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATF7IP activating transcription factor 7 interacting protein
BLK BLK proto-oncogene, Src family tyrosine kinase
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CCK cholecystokinin
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEL carboxyl ester lipase
CELA2A chymotrypsin-like elastase family, member 2A
CNTNAP2 contactin associated protein-like 2
COL10A1 collagen, type X, alpha 1
COL14A1 collagen, type XIV, alpha 1
CSN2 casein beta
CXCL5 chemokine (C-X-C motif) ligand 5
CXCR6 chemokine (C-X-C motif) receptor 6
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDN3 endothelin 3
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EYA3 EYA transcriptional coactivator and phosphatase 3
FGB fibrinogen beta chain
FGF8 fibroblast growth factor 8 (androgen-induced)
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
HEXIM1 hexamethylene bis-acetamide inducible 1
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HSF1 heat shock transcription factor 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IFNA2 interferon, alpha 2
IL18R1 interleukin 18 receptor 1
INADL InaD-like (Drosophila)
IQCA1 IQ motif containing with AAA domain 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
IZUMO4 IZUMO family member 4
JUND jun D proto-oncogene
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KMT2A lysine (K)-specific methyltransferase 2A
KRTAP5-9 keratin associated protein 5-9
KSR1 kinase suppressor of ras 1
LDB3 LIM domain binding 3
LGALS4 lectin, galactoside-binding, soluble, 4
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LOXL3 lysyl oxidase-like 3
MAP3K7CL MAP3K7 C-terminal like
MAU2 MAU2 sister chromatid cohesion factor
MFAP5 microfibrillar associated protein 5
MINK1 misshapen-like kinase 1
MPL MPL proto-oncogene, thrombopoietin receptor
MSI1 musashi RNA-binding protein 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPTX1 neuronal pentraxin I
NR2F6 nuclear receptor subfamily 2, group F, member 6
NRF1 nuclear respiratory factor 1
OCM2 oncomodulin 2
OGFR opioid growth factor receptor
OPRD1 opioid receptor, delta 1
OSBPL10 oxysterol binding protein-like 10
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE7B phosphodiesterase 7B
PGM5 phosphoglucomutase 5
PITX1 paired-like homeodomain 1
PPARA peroxisome proliferator-activated receptor alpha
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
RAB36 RAB36, member RAS oncogene family
RAG2 recombination activating gene 2
RCN3 reticulocalbin 3, EF-hand calcium binding domain
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS16 regulator of G-protein signaling 16
RHBG Rh family, B glycoprotein (gene/pseudogene)
SCGB2A1 secretoglobin, family 2A, member 1
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SPAG11A sperm associated antigen 11A
SPTBN5 spectrin, beta, non-erythrocytic 5
SRPK3 SRSF protein kinase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SUSD4 sushi domain containing 4
TBX6 T-box 6
TMEM212 transmembrane protein 212
TMEM257 transmembrane protein 257
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
ZFP36L2 ZFP36 ring finger protein-like 2
ZMIZ2 zinc finger, MIZ-type containing 2
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AKR1C4 aldo-keto reductase family 1, member C4
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARSB arylsulfatase B
BCL2L2 BCL2-like 2
C1ORF105 chromosome 1 open reading frame 105
C8A complement component 8, alpha polypeptide
CAMKMT calmodulin-lysine N-methyltransferase
CCDC9 coiled-coil domain containing 9
CDKL3 cyclin-dependent kinase-like 3
CES1 carboxylesterase 1
CIDEC cell death-inducing DFFA-like effector c
CLDN11 claudin 11
CNR2 cannabinoid receptor 2 (macrophage)
CNTLN centlein, centrosomal protein
CPB1 carboxypeptidase B1 (tissue)
CPED1 cadherin-like and PC-esterase domain containing 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAH7 dynein, axonemal, heavy chain 7
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ERAP2 endoplasmic reticulum aminopeptidase 2
ETNK2 ethanolamine kinase 2
EXOC6B exocyst complex component 6B
FGF13 fibroblast growth factor 13
FMO4 flavin containing monooxygenase 4
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GID4 GID complex subunit 4
GLT8D2 glycosyltransferase 8 domain containing 2
GMPR guanosine monophosphate reductase
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H3C histone cluster 1, H3c
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
HOXA6 homeobox A6
IDI2-AS1 IDI2 antisense RNA 1
IER3IP1 immediate early response 3 interacting protein 1
IFT54 intraflagellar transport 54
IPO8 importin 8
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA0319L KIAA0319-like
KRT86 keratin 86, type II
LENEP lens epithelial protein
LINC00341 long intergenic non-protein coding RNA 341
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MATN3 matrilin 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCMBP minichromosome maintenance complex binding protein
MFSD12 major facilitator superfamily domain containing 12
MMRN2 multimerin 2
MTCP1 mature T-cell proliferation 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDE1 nudE neurodevelopment protein 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PHF14 PHD finger protein 14
PLA2G1B phospholipase A2, group IB (pancreas)
PLD3 phospholipase D family, member 3
PLSCR4 phospholipid scramblase 4
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PWAR5 Prader Willi/Angelman region RNA 5
PXMP4 peroxisomal membrane protein 4, 24kDa
R3HCC1L R3H domain and coiled-coil containing 1-like
REPS2 RALBP1 associated Eps domain containing 2
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SELL selectin L
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SP1 Sp1 transcription factor
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STRN striatin, calmodulin binding protein
TECTA tectorin alpha
THBS3 thrombospondin 3
TM6SF1 transmembrane 6 superfamily member 1
TMEM159 transmembrane protein 159
TMEM242 transmembrane protein 242
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOM1 target of myb1 (chicken)
TWISTNB TWIST neighbor
VGF VGF nerve growth factor inducible
ZNF225 zinc finger protein 225
ZNF37BP zinc finger protein 37B, pseudogene
ZNF391 zinc finger protein 391
ZNF767P zinc finger family member 767, pseudogene
ZNF778 zinc finger protein 778
ZNF816 zinc finger protein 816