obese Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001261
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Genes

70 gene mutations causing the obese phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALMS1 Alstrom syndrome protein 1
ANGPTL6 angiopoietin-like 6
ANKRD26 ankyrin repeat domain 26
ASIP agouti signaling protein
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
BBIP1 BBSome interacting protein 1
BBS1 Bardet-Biedl syndrome 1
BBS12 Bardet-Biedl syndrome 12
BBS4 Bardet-Biedl syndrome 4
BDNF brain-derived neurotrophic factor
BRD2 bromodomain containing 2
BRS3 bombesin-like receptor 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEP19 centrosomal protein 19kDa
CPE carboxypeptidase E
CRH corticotropin releasing hormone
CRTC1 CREB regulated transcription coactivator 1
CSPG4 chondroitin sulfate proteoglycan 4
CTF1 cardiotrophin 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ESR1 estrogen receptor 1
FEN1 flap structure-specific endonuclease 1
FSHR follicle stimulating hormone receptor
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GNAS GNAS complex locus
GPR12 G protein-coupled receptor 12
HDC histidine decarboxylase
HOXC10 homeobox C10
IL6 interleukin 6
IRS2 insulin receptor substrate 2
KDM3A lysine (K)-specific demethylase 3A
KSR2 kinase suppressor of ras 2
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MKKS McKusick-Kaufman syndrome
MRAP2 melanocortin 2 receptor accessory protein 2
NCOA1 nuclear receptor coactivator 1
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NHLH2 nescient helix loop helix 2
NMU neuromedin U
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
PCSK1 proprotein convertase subtilisin/kexin type 1
PEX11A peroxisomal biogenesis factor 11 alpha
PLSCR3 phospholipid scramblase 3
POMC proopiomelanocortin
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PRLH prolactin releasing hormone
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYY peptide YY
RAI1 retinoic acid induced 1
RB1 retinoblastoma 1
RSC1A1 regulatory solute carrier protein, family 1, member 1
SELM selenoprotein M
SIM1 single-minded family bHLH transcription factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
TERF2IP telomeric repeat binding factor 2, interacting protein
THRA thyroid hormone receptor, alpha
TLR5 toll-like receptor 5
TTC8 tetratricopeptide repeat domain 8
TUB tubby bipartite transcription factor
TYK2 tyrosine kinase 2
WDTC1 WD and tetratricopeptide repeats 1
ZEB1 zinc finger E-box binding homeobox 1