obstructive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

294 genes co-occuring with the biological term obstructive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACE angiotensin I converting enzyme
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM29 ADAM metallopeptidase domain 29
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA2B adenosine A2b receptor
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHSG alpha-2-HS-glycoprotein
ALB albumin
AMH anti-Mullerian hormone
APLN apelin
APOE apolipoprotein E
APTX aprataxin
AQP5 aquaporin 5
AVP arginine vasopressin
B3GAT1 beta-1,3-glucuronyltransferase 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BDKRB1 bradykinin receptor B1
BDNF brain-derived neurotrophic factor
C3AR1 complement component 3a receptor 1
C4A complement component 4A (Rodgers blood group)
C5AR1 complement component 5a receptor 1
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CAV1 caveolin 1, caveolae protein, 22kDa
CCL11 chemokine (C-C motif) ligand 11
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CCL5 chemokine (C-C motif) ligand 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR8 chemokine (C-C motif) receptor 8
CD14 CD14 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD63 CD63 molecule
CD86 CD86 molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIA chitinase, acidic
CHIT1 chitinase 1 (chitotriosidase)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CKMT1B creatine kinase, mitochondrial 1B
CLCA1 chloride channel accessory 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A5 collagen, type VI, alpha 5
COX2
CRISP1 cysteine-rich secretory protein 1
CRP C-reactive protein, pentraxin-related
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR6 chemokine (C-X-C motif) receptor 6
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2F1 cytochrome P450, family 2, subfamily F, polypeptide 1
DDR1 discoidin domain receptor tyrosine kinase 1
DDR2 discoidin domain receptor tyrosine kinase 2
DEFB1 defensin, beta 1
DUOX1 dual oxidase 1
DUOX2 dual oxidase 2
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
ELN elastin
ENO2 enolase 2 (gamma, neuronal)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EPO erythropoietin
F11 coagulation factor XI
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FAM13A family with sequence similarity 13, member A
FANCC Fanconi anemia, complementation group C
FFAR4 free fatty acid receptor 4
FGF7 fibroblast growth factor 7
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXA3 forkhead box A3
FOXO3 forkhead box O3
FOXP3 forkhead box P3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GC group-specific component (vitamin D binding protein)
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GPR182 G protein-coupled receptor 182
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTM3 glutathione S-transferase mu 3 (brain)
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAVCR1 hepatitis A virus cellular receptor 1
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HCRT hypocretin (orexin) neuropeptide precursor
HDAC2 histone deacetylase 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPG2 heparan sulfate proteoglycan 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL16 interleukin 16
IL17A interleukin 17A
IL17F interleukin 17F
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL33R interleukin 33 receptor
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
IREB2 iron-responsive element binding protein 2
IRS1 insulin receptor substrate 1
ITLN1 intelectin 1 (galactofuranose binding)
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KDR kinase insert domain receptor
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRT18 keratin 18, type I
L1CAM L1 cell adhesion molecule
LBP lipopolysaccharide binding protein
LCN2 lipocalin 2
LEP leptin
LEPR leptin receptor
LPL lipoprotein lipase
LTC4S leukotriene C4 synthase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MBL2 mannose-binding lectin (protein C) 2, soluble
MCL1 myeloid cell leukemia 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR101-1 microRNA 101-1
MIR144 microRNA 144
MIR181A1 microRNA 181a-1
MIR199A1 microRNA 199a-1
MIR199A2 microRNA 199a-2
MIR21 microRNA 21
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC16 mucin 16, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFE2L2 nuclear factor, erythroid 2-like 2
NGF nerve growth factor (beta polypeptide)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OSM oncostatin M
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PDGFD platelet derived growth factor D
PER1 period circadian clock 1
PI3 peptidase inhibitor 3, skin-derived
PIGR polymeric immunoglobulin receptor
PLA2G2D phospholipase A2, group IID
PLAUR plasminogen activator, urokinase receptor
PLG plasminogen
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PRLR prolactin receptor
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP4 retinol binding protein 4, plasma
RETN resistin
RNASE3 ribonuclease, RNase A family, 3
RXRA retinoid X receptor, alpha
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPD surfactant protein D
SIRT2 sirtuin 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SOD2 superoxide dismutase 2, mitochondrial
SOD3 superoxide dismutase 3, extracellular
SP1 Sp1 transcription factor
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPP1 secreted phosphoprotein 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRXN1 sulfiredoxin 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TNC tenascin C
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TNP1 transition protein 1 (during histone to protamine replacement)
TP53 tumor protein p53
TRA T cell receptor alpha locus
TREM1 triggering receptor expressed on myeloid cells 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSLP thymic stromal lymphopoietin
USP26 ubiquitin specific peptidase 26
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VWF von Willebrand factor
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta