occluding junction Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. (Gene Ontology, GO_0070160)
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Genes

99 proteins localized to the occluding junction cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CLDN18 claudin 18 0.663342
CLDN4 claudin 4 0.663342
CLDN9 claudin 9 0.663342
ECT2 epithelial cell transforming 2 0.663342
BVES blood vessel epicardial substance 0.663342
CRB3 crumbs family member 3 0.663342
RAB13 RAB13, member RAS oncogene family 0.663342
PLXDC1 plexin domain containing 1 0.663342
INADL InaD-like (Drosophila) 0.663342
TJP1 tight junction protein 1 0.663342
TJP3 tight junction protein 3 0.663342
TJP2 tight junction protein 2 0.663342
TGFBR1 transforming growth factor, beta receptor 1 0.663342
PARD6A par-6 family cell polarity regulator alpha 0.663342
PARD6B par-6 family cell polarity regulator beta 0.663342
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.663342
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) 0.663342
CLDN5 claudin 5 0.663342
CLDN7 claudin 7 0.663342
CLDN8 claudin 8 0.663342
CLDN15 claudin 15 0.663342
CLDN14 claudin 14 0.663342
CLDN17 claudin 17 0.663342
CLDN16 claudin 16 0.663342
CLDN11 claudin 11 0.663342
CLDN12 claudin 12 0.663342
UBN1 ubinuclein 1 0.663342
OCLN occludin 0.663342
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.663342
AMOT angiomotin 0.663342
MPDZ multiple PDZ domain protein 0.663342
ARHGAP17 Rho GTPase activating protein 17 0.663342
CLDN20 claudin 20 0.663342
CLDN19 claudin 19 0.663342
NPHP4 nephronophthisis 4 0.663342
NPHP1 nephronophthisis 1 (juvenile) 0.663342
STRN striatin, calmodulin binding protein 0.663342
CLDN1 claudin 1 0.663342
PARD3B par-3 family cell polarity regulator beta 0.663342
APC adenomatous polyposis coli 0.663342
AMICA1 adhesion molecule, interacts with CXADR antigen 1 0.663342
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.663342
CGN cingulin 0.663342
RPGRIP1L RPGRIP1-like 0.663342
AMOTL1 angiomotin like 1 0.663342
PARD3 par-3 family cell polarity regulator 0.663342
FRMPD2 FERM and PDZ domain containing 2 0.663342
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.663342
CLMP CXADR-like membrane protein 0.663342
CXADR coxsackie virus and adenovirus receptor 0.663342
EPCAM epithelial cell adhesion molecule 0.663342
SYMPK symplekin 0.663342
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.663342
MARVELD3 MARVEL domain containing 3 0.237908
CLDN6 claudin 6 0.237908
SHROOM2 shroom family member 2 0.237908
CLDN10 claudin 10 0.237908
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 0.237908
CLDN2 claudin 2 0.237908
CLDN22 claudin 22 0.237908
TBCD tubulin folding cofactor D 0.237908
WNK4 WNK lysine deficient protein kinase 4 0.237908
DLG1 discs, large homolog 1 (Drosophila) 0.237908
MARVELD2 MARVEL domain containing 2 0.237908
MICALL2 MICAL-like 2 0.237908
MTDH metadherin 0.237908
JAM2 junctional adhesion molecule 2 0.098109
TJAP1 tight junction associated protein 1 (peripheral) 0.098109
SYNPO synaptopodin 0.098109
PARD6G par-6 family cell polarity regulator gamma 0.098109
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.098109
LIN7B lin-7 homolog B (C. elegans) 0.098109
F11R F11 receptor 0.098109
LIN7C lin-7 homolog C (C. elegans) 0.098109
VASP vasodilator-stimulated phosphoprotein 0.098109
CLDN24 claudin 24 0.098109
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 0.098109
CLDN3 claudin 3 0.098109
TRAF4 TNF receptor-associated factor 4 0.098109
ESAM endothelial cell adhesion molecule 0.098109
YBX3 Y box binding protein 3 0.098109
POF1B premature ovarian failure, 1B 0.098109
CCDC85C coiled-coil domain containing 85C 0.098109
WNK3 WNK lysine deficient protein kinase 3 0.098109
IGSF5 immunoglobulin superfamily, member 5 0.098109
CGNL1 cingulin-like 1 0.098109
CLDN25 claudin 25 0.098109
LIN7A lin-7 homolog A (C. elegans) 0.098109
JAM3 junctional adhesion molecule 3 0.03318
CYTH1 cytohesin 1 0.03318
CCND1 cyclin D1 0.03318
FRMD4A FERM domain containing 4A 0.03318
AMOTL2 angiomotin like 2 0.03318
PRKCZ protein kinase C, zeta 0.03318
CDK4 cyclin-dependent kinase 4 0.03318
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.03318
FZD5 frizzled class receptor 5 0.03318
DLG3 discs, large homolog 3 (Drosophila) 0.03318
CDH5 cadherin 5, type 2 (vascular endothelium) 0.03318