octopamine-6491 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the octopamine-6491 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALDOB aldolase B, fructose-bisphosphate
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALS2CL ALS2 C-terminal like
APC2 adenomatosis polyposis coli 2
APOM apolipoprotein M
C21ORF2 chromosome 21 open reading frame 2
C2ORF27A chromosome 2 open reading frame 27A
CA9 carbonic anhydrase IX
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAV2 caveolin 2
CCDC40 coiled-coil domain containing 40
CCDC85B coiled-coil domain containing 85B
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD6 CD6 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDRT1 CMT1A duplicated region transcript 1
CFAP70 cilia and flagella associated protein 70
CLGN calmegin
CSF1 colony stimulating factor 1 (macrophage)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DPYS dihydropyrimidinase
EFNA3 ephrin-A3
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F5 coagulation factor V (proaccelerin, labile factor)
FGF2 fibroblast growth factor 2 (basic)
FOLR1 folate receptor 1 (adult)
GALR3 galanin receptor 3
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GKN1 gastrokine 1
GLUL glutamate-ammonia ligase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNRHR gonadotropin-releasing hormone receptor
GYG2 glycogenin 2
HIST1H4D histone cluster 1, H4d
HP1BP3 heterochromatin protein 1, binding protein 3
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
ICAM1 intercellular adhesion molecule 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ISG20 interferon stimulated exonuclease gene 20kDa
KCTD20 potassium channel tetramerization domain containing 20
KLF12 Kruppel-like factor 12
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT24 keratin 24, type I
KSR1 kinase suppressor of ras 1
LMF2 lipase maturation factor 2
LRP1 low density lipoprotein receptor-related protein 1
MAPK13 mitogen-activated protein kinase 13
MASP2 mannan-binding lectin serine peptidase 2
MAST2 microtubule associated serine/threonine kinase 2
MBNL2 muscleblind-like splicing regulator 2
MPL MPL proto-oncogene, thrombopoietin receptor
MST1 macrophage stimulating 1
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO7A myosin VIIA
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NEUROD1 neuronal differentiation 1
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
NREP neuronal regeneration related protein
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PDE4DIP phosphodiesterase 4D interacting protein
PHF8 PHD finger protein 8
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLCD1 phospholipase C, delta 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RANGAP1 Ran GTPase activating protein 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RDH8 retinol dehydrogenase 8 (all-trans)
RER1 retention in endoplasmic reticulum sorting receptor 1
RRAGB Ras-related GTP binding B
RUNX1 runt-related transcription factor 1
SAMD9 sterile alpha motif domain containing 9
SH3BP2 SH3-domain binding protein 2
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SMYD2 SET and MYND domain containing 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STK19 serine/threonine kinase 19
TCTN1 tectonic family member 1
TIMP3 TIMP metallopeptidase inhibitor 3
TRIM10 tripartite motif containing 10
WDR62 WD repeat domain 62
WISP3 WNT1 inducible signaling pathway protein 3
WNT2 wingless-type MMTV integration site family member 2
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ADGRG2 adhesion G protein-coupled receptor G2
ANKRD36 ankyrin repeat domain 36
ARMC6 armadillo repeat containing 6
ARR3 arrestin 3, retinal (X-arrestin)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD3A ATPase family, AAA domain containing 3A
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
BIRC7 baculoviral IAP repeat containing 7
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5AR2 complement component 5a receptor 2
C5ORF45 chromosome 5 open reading frame 45
C9ORF9 chromosome 9 open reading frame 9
CAPN5 calpain 5
CCDC132 coiled-coil domain containing 132
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CLEC16A C-type lectin domain family 16, member A
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRELD1 cysteine-rich with EGF-like domains 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCAF13 DDB1 and CUL4 associated factor 13
DDIT3 DNA-damage-inducible transcript 3
DGKE diacylglycerol kinase, epsilon 64kDa
DOCK4 dedicator of cytokinesis 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDC3 enhancer of mRNA decapping 3
FAM186A family with sequence similarity 186, member A
FBXL6 F-box and leucine-rich repeat protein 6
GADD45G growth arrest and DNA-damage-inducible, gamma
GLI3 GLI family zinc finger 3
GRPR gastrin-releasing peptide receptor
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAMP hepcidin antimicrobial peptide
HIRA histone cell cycle regulator
HIST1H4F histone cluster 1, H4f
HMHA1 histocompatibility (minor) HA-1
HOXB2 homeobox B2
HYI hydroxypyruvate isomerase (putative)
IFT81 intraflagellar transport 81
IGFBP6 insulin-like growth factor binding protein 6
INF2 inverted formin, FH2 and WH2 domain containing
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL25 kelch-like family member 25
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMNB1 lamin B1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC20 leucine rich repeat containing 20
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MGC12488
MMP2 matrix metallopeptidase 2
MXD3 MAX dimerization protein 3
N4BP3 NEDD4 binding protein 3
NECAB3 N-terminal EF-hand calcium binding protein 3
NOL12 nucleolar protein 12
NR1H2 nuclear receptor subfamily 1, group H, member 2
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDGFD platelet derived growth factor D
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLD2 phospholipase D2
PRAF2 PRA1 domain family, member 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
QPCT glutaminyl-peptide cyclotransferase
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RGS2 regulator of G-protein signaling 2
RNF123 ring finger protein 123
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SH2D4A SH2 domain containing 4A
SHARPIN SHANK-associated RH domain interactor
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOX3 SRY (sex determining region Y)-box 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STIM1 stromal interaction molecule 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
TMEM180 transmembrane protein 180
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAIP TRAF interacting protein
UBQLN4 ubiquilin 4
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF432 zinc finger protein 432
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZXDC ZXD family zinc finger C