| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the ofloxacin-2302 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADD2 | adducin 2 (beta) |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AIRE | autoimmune regulator |
| AK1 | adenylate kinase 1 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX5 | arachidonate 5-lipoxygenase |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA10 | carbonic anhydrase X |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CD53 | CD53 molecule |
| CD82 | CD82 molecule |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAH9 | dynein, axonemal, heavy chain 9 |
| DOC2A | double C2-like domains, alpha |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EXOSC1 | exosome component 1 |
| FAM155A | family with sequence similarity 155, member A |
| FAM76A | family with sequence similarity 76, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FOXN3 | forkhead box N3 |
| FRMD1 | FERM domain containing 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GUK1 | guanylate kinase 1 |
| HRH2 | histamine receptor H2 |
| IDUA | iduronidase, alpha-L- |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL23A | interleukin 23, alpha subunit p19 |
| IRS4 | insulin receptor substrate 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| JAK3 | Janus kinase 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KDR | kinase insert domain receptor |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT15 | keratin 15, type I |
| KRT83 | keratin 83, type II |
| LAMB4 | laminin, beta 4 |
| LMTK1 | lemur tail kinase 1 |
| LOC729164 | hCG1732469 |
| LRRC61 | leucine rich repeat containing 61 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NOX1 | NADPH oxidase 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCDH1 | protocadherin 1 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTRF | polymerase I and transcript release factor |
| PYY | peptide YY |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REC8 | REC8 meiotic recombination protein |
| RFPL1S | RFPL1 antisense RNA 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| SARDH | sarcosine dehydrogenase |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC17A6 | solute carrier family 17 (vesicular glutamate transporter), member 6 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SNCAIP | synuclein, alpha interacting protein |
| SRRT | serrate, RNA effector molecule |
| STK17A | serine/threonine kinase 17a |
| TBXA2R | thromboxane A2 receptor |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TLN1 | talin 1 |
| TMEM212 | transmembrane protein 212 |
| TOP3B | topoisomerase (DNA) III beta |
| TP73-AS1 | TP73 antisense RNA 1 |
| TRAIP | TRAF interacting protein |
| TSC22D4 | TSC22 domain family, member 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VCX2 | variable charge, X-linked 2 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF350 | zinc finger protein 350 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABHD17B | abhydrolase domain containing 17B |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADM | adrenomedullin |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNK | cyclin K |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| DUSP2 | dual specificity phosphatase 2 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| ESRP2 | epithelial splicing regulatory protein 2 |
| ETNK2 | ethanolamine kinase 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FANCC | Fanconi anemia, complementation group C |
| FBXO2 | F-box protein 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPATCH2L | G patch domain containing 2-like |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2BI | histone cluster 1, H2bi |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KEL | Kell blood group, metallo-endopeptidase |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| KIFAP3 | kinesin-associated protein 3 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAGEB2 | melanoma antigen family B2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MATK | megakaryocyte-associated tyrosine kinase |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OLFML2A | olfactomedin-like 2A |
| OSMR | oncostatin M receptor |
| PALM | paralemmin |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLL | polymerase (DNA directed), lambda |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF170 | ring finger protein 170 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2B3 | SH2B adaptor protein 3 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLN | sarcolipin |
| SP1 | Sp1 transcription factor |
| ST5 | suppression of tumorigenicity 5 |
| TCTN2 | tectonic family member 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLR2 | toll-like receptor 2 |
| TRIM25 | tripartite motif containing 25 |
| TRIM68 | tripartite motif containing 68 |
| TUBA3C | tubulin, alpha 3c |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VPS9D1 | VPS9 domain containing 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF227 | zinc finger protein 227 |
| ZNF365 | zinc finger protein 365 |
| ZNF480 | zinc finger protein 480 |
| ZNF506 | zinc finger protein 506 |
| ZNF586 | zinc finger protein 586 |
