| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ofloxacin-2340 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ADA | adenosine deaminase |
| ADD2 | adducin 2 (beta) |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| APOC1 | apolipoprotein C-I |
| ARG1 | arginase 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BHMT | betaine--homocysteine S-methyltransferase |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CD82 | CD82 molecule |
| CDC14A | cell division cycle 14A |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHPF | chondroitin polymerizing factor |
| CHST10 | carbohydrate sulfotransferase 10 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNTN1 | contactin 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNND1 | catenin (cadherin-associated protein), delta 1 |
| CTSV | cathepsin V |
| CUL3 | cullin 3 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| E2F5 | E2F transcription factor 5, p130-binding |
| EDNRB | endothelin receptor type B |
| ERP44 | endoplasmic reticulum protein 44 |
| EXOSC2 | exosome component 2 |
| FGF5 | fibroblast growth factor 5 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FRMD1 | FERM domain containing 1 |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPR137 | G protein-coupled receptor 137 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HPR | haptoglobin-related protein |
| IL1R2 | interleukin 1 receptor, type II |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLHL25 | kelch-like family member 25 |
| KRT17 | keratin 17, type I |
| LOC257152 | uncharacterized LOC257152 |
| LOC392555 | melanoma antigen family C2 pseudogene |
| LOC647070 | uncharacterized LOC647070 |
| LOXL3 | lysyl oxidase-like 3 |
| MEFV | Mediterranean fever |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| NF1 | neurofibromin 1 |
| NTF3 | neurotrophin 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PCYT1A | phosphate cytidylyltransferase 1, choline, alpha |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma |
| PRSS53 | protease, serine, 53 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSKH1 | protein serine kinase H1 |
| PSPH | phosphoserine phosphatase |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REST | RE1-silencing transcription factor |
| RET | ret proto-oncogene |
| S100A6 | S100 calcium binding protein A6 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SSH3 | slingshot protein phosphatase 3 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBC1D30 | TBC1 domain family, member 30 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNS1 | tensin 1 |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UBE3B | ubiquitin protein ligase E3B |
| VN1R1 | vomeronasal 1 receptor 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF202 | zinc finger protein 202 |
| ZNF354A | zinc finger protein 354A |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGO4 | argonaute RISC catalytic component 4 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARSB | arylsulfatase B |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CDA | cytidine deaminase |
| CDK3 | cyclin-dependent kinase 3 |
| CEL | carboxyl ester lipase |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHMP7 | charged multivesicular body protein 7 |
| CIC | capicua transcriptional repressor |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CREB3 | cAMP responsive element binding protein 3 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DGKD | diacylglycerol kinase, delta 130kDa |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DUSP5 | dual specificity phosphatase 5 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM172A | family with sequence similarity 172, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FLCN | folliculin |
| FUZ | fuzzy planar cell polarity protein |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2BF | histone cluster 1, H2bf |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IL4R | interleukin 4 receptor |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JOSD1 | Josephin domain containing 1 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MANBA | mannosidase, beta A, lysosomal |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MEF2D | myocyte enhancer factor 2D |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTMR12 | myotubularin related protein 12 |
| MYO15A | myosin XVA |
| NBEAL2 | neurobeachin-like 2 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| P3H1 | prolyl 3-hydroxylase 1 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLS1 | plastin 1 |
| PMCH | pro-melanin-concentrating hormone |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PRKX | protein kinase, X-linked |
| PTGES2 | prostaglandin E synthase 2 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB33B | RAB33B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBM47 | RNA binding motif protein 47 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLFN12 | schlafen family member 12 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SSBP3 | single stranded DNA binding protein 3 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TMEM212 | transmembrane protein 212 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| WDR91 | WD repeat domain 91 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF552 | zinc finger protein 552 |
| ZNF629 | zinc finger protein 629 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
