| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the ofloxacin-3673 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing |
| AJAP1 | adherens junctions associated protein 1 |
| ANGPT1 | angiopoietin 1 |
| APOB | apolipoprotein B |
| ATG10 | autophagy related 10 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD5 | CD5 molecule |
| CFAP45 | cilia and flagella associated protein 45 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CT62 | cancer/testis antigen 62 |
| CYBB | cytochrome b-245, beta polypeptide |
| DAPK2 | death-associated protein kinase 2 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| EMC3 | ER membrane protein complex subunit 3 |
| EPHA5 | EPH receptor A5 |
| FGL2 | fibrinogen-like 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXO4 | forkhead box O4 |
| FZD1 | frizzled class receptor 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALC | galactosylceramidase |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR27 | G protein-coupled receptor 27 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HAL | histidine ammonia-lyase |
| HBE1 | hemoglobin, epsilon 1 |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| IRF4 | interferon regulatory factor 4 |
| ITGA7 | integrin, alpha 7 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAM2 | junctional adhesion molecule 2 |
| KLHL18 | kelch-like family member 18 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT1 | keratin 1, type II |
| KRT24 | keratin 24, type I |
| KRTAP1-1 | keratin associated protein 1-1 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LCAT | lecithin-cholesterol acyltransferase |
| LDAH | lipid droplet associated hydrolase |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED16 | mediator complex subunit 16 |
| MEF2D | myocyte enhancer factor 2D |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MYH14 | myosin, heavy chain 14, non-muscle |
| N4BP1 | NEDD4 binding protein 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRP1 | neuropilin 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PER2 | period circadian clock 2 |
| PHOX2B | paired-like homeobox 2b |
| POU3F4 | POU class 3 homeobox 4 |
| PRKCE | protein kinase C, epsilon |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTEN | phosphatase and tensin homolog |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SFRP4 | secreted frizzled-related protein 4 |
| SFTPB | surfactant protein B |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SNN | stannin |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRR2B | small proline-rich protein 2B |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SYT2 | synaptotagmin II |
| TACR1 | tachykinin receptor 1 |
| TBX5 | T-box 5 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TUBAL3 | tubulin, alpha-like 3 |
| UPK1B | uroplakin 1B |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF345 | zinc finger protein 345 |
| ZNF362 | zinc finger protein 362 |
| Symbol | Name |
|---|---|
| AMT | aminomethyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATXN2 | ataxin 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC106 | coiled-coil domain containing 106 |
| CCDC121 | coiled-coil domain containing 121 |
| CCNJL | cyclin J-like |
| CDHR2 | cadherin-related family member 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTLN | centlein, centrosomal protein |
| COBL | cordon-bleu WH2 repeat protein |
| CORO2A | coronin, actin binding protein, 2A |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DEAF1 | DEAF1 transcription factor |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DIO3 | deiodinase, iodothyronine, type III |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP2 | dual specificity phosphatase 2 |
| EFNB1 | ephrin-B1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EXOC6B | exocyst complex component 6B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR176 | G protein-coupled receptor 176 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3C | histone cluster 1, H3c |
| IL22 | interleukin 22 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KRT4 | keratin 4, type II |
| LAMC3 | laminin, gamma 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LOC157562 | uncharacterized LOC157562 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAK | male germ cell-associated kinase |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MEGF8 | multiple EGF-like-domains 8 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDP | Norrie disease (pseudoglioma) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PADI1 | peptidyl arginine deiminase, type I |
| PDGFRL | platelet-derived growth factor receptor-like |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHF14 | PHD finger protein 14 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PODXL2 | podocalyxin-like 2 |
| POLM | polymerase (DNA directed), mu |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKCD | protein kinase C, delta |
| PRPH | peripherin |
| RAB28 | RAB28, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHBDD3 | rhomboid domain containing 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SETD1A | SET domain containing 1A |
| SMO | smoothened, frizzled class receptor |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SNTG1 | syntrophin, gamma 1 |
| ST6GALNAC5 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| TBC1D19 | TBC1 domain family, member 19 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM212 | transmembrane protein 212 |
| TUBA3C | tubulin, alpha 3c |
| USP20 | ubiquitin specific peptidase 20 |
| VGF | VGF nerve growth factor inducible |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF573 | zinc finger protein 573 |
| ZNF76 | zinc finger protein 76 |