| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the ofloxacin-4696 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| AGFG1 | ArfGAP with FG repeats 1 |
| AK1 | adenylate kinase 1 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGAP24 | Rho GTPase activating protein 24 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BTG2 | BTG family, member 2 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCDC186 | coiled-coil domain containing 186 |
| CD7 | CD7 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK13 | cyclin-dependent kinase 13 |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COL8A1 | collagen, type VIII, alpha 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAI2 | dynein, axonemal, intermediate chain 2 |
| DNM3 | dynamin 3 |
| EDNRA | endothelin receptor type A |
| EFNB3 | ephrin-B3 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EPHB2 | EPH receptor B2 |
| ETV6 | ets variant 6 |
| FGFR1 | fibroblast growth factor receptor 1 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| GNAT1 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR137 | G protein-coupled receptor 137 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4A | histone cluster 1, H4a |
| HLF | hepatic leukemia factor |
| HOXB5 | homeobox B5 |
| IGL | immunoglobulin lambda locus |
| IL5RA | interleukin 5 receptor, alpha |
| IQCK | IQ motif containing K |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| LAMA4 | laminin, alpha 4 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOXL2 | lysyl oxidase-like 2 |
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 |
| MCAM | melanoma cell adhesion molecule |
| MED31 | mediator complex subunit 31 |
| MID1 | midline 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| NRN1 | neuritin 1 |
| OLFML2A | olfactomedin-like 2A |
| ONECUT2 | one cut homeobox 2 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PAPPA2 | pappalysin 2 |
| PARVA | parvin, alpha |
| PCDHA5 | protocadherin alpha 5 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDLIM3 | PDZ and LIM domain 3 |
| PIP | prolactin-induced protein |
| PLAC4 | placenta-specific 4 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| POLR2J4 | polymerase (RNA) II (DNA directed) polypeptide J4, pseudogene |
| POU5F1B | POU class 5 homeobox 1B |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| QSER1 | glutamine and serine rich 1 |
| RBM26 | RNA binding motif protein 26 |
| RPL35A | ribosomal protein L35a |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBX3 | T-box 3 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TOX3 | TOX high mobility group box family member 3 |
| TRIM10 | tripartite motif containing 10 |
| TUBA3C | tubulin, alpha 3c |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF304 | zinc finger protein 304 |
| ZNF41 | zinc finger protein 41 |
| ZNF415 | zinc finger protein 415 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARC | activity-regulated cytoskeleton-associated protein |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC9 | coiled-coil domain containing 9 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CEL | carboxyl ester lipase |
| CENPO | centromere protein O |
| CIDEC | cell death-inducing DFFA-like effector c |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLIC2 | chloride intracellular channel 2 |
| CORO7 | coronin 7 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM204A | family with sequence similarity 204, member A |
| FLJ22184 | |
| FUZ | fuzzy planar cell polarity protein |
| GLRA1 | glycine receptor, alpha 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPC3 | glypican 3 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IPO8 | importin 8 |
| KIF13A | kinesin family member 13A |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LHX6 | LIM homeobox 6 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC23 | leucine rich repeat containing 23 |
| MGC12488 | |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MXD3 | MAX dimerization protein 3 |
| MYLK | myosin light chain kinase |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NUPL2 | nucleoporin like 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSMR | oncostatin M receptor |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PLAT | plasminogen activator, tissue |
| PMEL | premelanosome protein |
| POLH | polymerase (DNA directed), eta |
| PP14571 | uncharacterized LOC100130449 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRR4 | proline rich 4 (lacrimal) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB33B | RAB33B, member RAS oncogene family |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF208 | ring finger protein 208 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPAG7 | sperm associated antigen 7 |
| SPATA2L | spermatogenesis associated 2-like |
| SPRR2B | small proline-rich protein 2B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TDRD12 | tudor domain containing 12 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM53 | transmembrane protein 53 |
| TNRC6B | trinucleotide repeat containing 6B |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH1 | vasohibin 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF219 | zinc finger protein 219 |
| ZNF428 | zinc finger protein 428 |
