| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
194 genes differentially expressed following the ofloxacin-7372 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ANXA10 | annexin A10 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCDC9 | coiled-coil domain containing 9 |
| CEP131 | centrosomal protein 131kDa |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLEC4E | C-type lectin domain family 4, member E |
| COL4A6 | collagen, type IV, alpha 6 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CSPP1 | centrosome and spindle pole associated protein 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DUSP9 | dual specificity phosphatase 9 |
| ECE1 | endothelin converting enzyme 1 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FGFR2 | fibroblast growth factor receptor 2 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FMOD | fibromodulin |
| FOSL2 | FOS-like antigen 2 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GLRB | glycine receptor, beta |
| GPR137 | G protein-coupled receptor 137 |
| GPSM3 | G-protein signaling modulator 3 |
| GRK6 | G protein-coupled receptor kinase 6 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGLJ3 | immunoglobulin lambda joining 3 |
| INSR | insulin receptor |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIF5C | kinesin family member 5C |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIMK2 | LIM domain kinase 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| NF2 | neurofibromin 2 (merlin) |
| NPR3 | natriuretic peptide receptor 3 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDS5A | PDS5 cohesin associated factor A |
| PRR4 | proline rich 4 (lacrimal) |
| PVR | poliovirus receptor |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB31 | RAB31, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RHOT2 | ras homolog family member T2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| RPS3A | ribosomal protein S3A |
| RUSC2 | RUN and SH3 domain containing 2 |
| SDC2 | syndecan 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TAOK2 | TAO kinase 2 |
| TAPBP | TAP binding protein (tapasin) |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TBX2 | T-box 2 |
| TESK1 | testis-specific kinase 1 |
| TGFA | transforming growth factor, alpha |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLN2 | talin 2 |
| TMEM121 | transmembrane protein 121 |
| TMEM63A | transmembrane protein 63A |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TUBA3C | tubulin, alpha 3c |
| UBE3B | ubiquitin protein ligase E3B |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| XDH | xanthine dehydrogenase |
| YY1 | YY1 transcription factor |
| ZNF174 | zinc finger protein 174 |
| ZNF224 | zinc finger protein 224 |
| ZNF358 | zinc finger protein 358 |
| ZNF428 | zinc finger protein 428 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| AFAP1 | actin filament associated protein 1 |
| AKTIP | AKT interacting protein |
| ALPK1 | alpha-kinase 1 |
| APOL6 | apolipoprotein L, 6 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC6 | armadillo repeat containing 6 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC68 | coiled-coil domain containing 68 |
| CCNO | cyclin O |
| CCS | copper chaperone for superoxide dismutase |
| CDON | cell adhesion associated, oncogene regulated |
| CENPO | centromere protein O |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC10A | C-type lectin domain family 10, member A |
| CLEC2B | C-type lectin domain family 2, member B |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSK | cathepsin K |
| DBR1 | debranching RNA lariats 1 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| FAM50B | family with sequence similarity 50, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| GALK1 | galactokinase 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BJ | histone cluster 1, H2bj |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KLF2 | Kruppel-like factor 2 |
| KRT6A | keratin 6A, type II |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MDFI | MyoD family inhibitor |
| MOXD1 | monooxygenase, DBH-like 1 |
| NHLRC2 | NHL repeat containing 2 |
| NOL12 | nucleolar protein 12 |
| NRBP1 | nuclear receptor binding protein 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| REEP4 | receptor accessory protein 4 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SAMHD1 | SAM domain and HD domain 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SERTAD3 | SERTA domain containing 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMAD7 | SMAD family member 7 |
| SPAG7 | sperm associated antigen 7 |
| SPEG | SPEG complex locus |
| TLR2 | toll-like receptor 2 |
| TMEM8A | transmembrane protein 8A |
| TMEM8B | transmembrane protein 8B |
| TNS2 | tensin 2 |
| TSPYL2 | TSPY-like 2 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| YOD1 | YOD1 deubiquitinase |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF253 | zinc finger protein 253 |
| ZNF408 | zinc finger protein 408 |
| ZNF480 | zinc finger protein 480 |
