| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEIS2 | Meis homeobox 2 | 0.0894398 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0800244 |
| DST | dystonin | 0.0741224 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0678532 |
| FAM13A | family with sequence similarity 13, member A | 0.0567594 |
| COL3A1 | collagen, type III, alpha 1 | 0.0529707 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0525178 |
| KLHL13 | kelch-like family member 13 | 0.0494272 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0464624 |
| AHNAK | AHNAK nucleoprotein | 0.0458558 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0455264 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0452231 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0432751 |
| NDRG1 | N-myc downstream regulated 1 | 0.0429654 |
| VIM | vimentin | 0.0421228 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0420756 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0410589 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0407478 |
| CADM2 | cell adhesion molecule 2 | 0.0400339 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0398239 |
| FNIP1 | folliculin interacting protein 1 | 0.0394142 |
| CENPF | centromere protein F, 350/400kDa | 0.0391886 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0389558 |
| ZNF292 | zinc finger protein 292 | 0.0378504 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0367793 |
| RPL37A | ribosomal protein L37a | 0.0352761 |
| TMSB10 | thymosin beta 10 | 0.0351911 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0351441 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0349336 |
| RNF145 | ring finger protein 145 | 0.0347679 |
| LPIN1 | lipin 1 | 0.0331633 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0325535 |
| SFTPA2 | surfactant protein A2 | 0.0325072 |
| YEATS2 | YEATS domain containing 2 | 0.0324097 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0322101 |
| PRKD1 | protein kinase D1 | 0.0312191 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0312055 |
| RPS6 | ribosomal protein S6 | 0.0311829 |
| DISP1 | dispatched homolog 1 (Drosophila) | 0.0309888 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0308482 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0304005 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0303762 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0303213 |
| PCDH15 | protocadherin-related 15 | 0.0302155 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0302084 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0301693 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0300046 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0297714 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0297286 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.028496 |
| SYT1 | synaptotagmin I | 0.0282882 |
| RPL7A | ribosomal protein L7a | 0.0281574 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0279575 |
| TULP4 | tubby like protein 4 | 0.0277782 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0277032 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0275865 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0274979 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0272914 |
| PTEN | phosphatase and tensin homolog | 0.0268919 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0267762 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.0267542 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0267322 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0267147 |
| AOPEP | aminopeptidase O (putative) | 0.0267081 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0266189 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0264988 |
| PLPP1 | phospholipid phosphatase 1 | 0.0264165 |
| RPS17 | ribosomal protein S17 | 0.0262827 |
| NRP1 | neuropilin 1 | 0.0262235 |
| MATR3 | matrin 3 | 0.0260493 |
| ZNF146 | zinc finger protein 146 | 0.0260464 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0256998 |
| NBEA | neurobeachin | 0.0250341 |
| GOSR1 | golgi SNAP receptor complex member 1 | 0.0248829 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0248478 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0247533 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0247443 |
| RNF213 | ring finger protein 213 | 0.0247239 |
| RUNX1 | runt-related transcription factor 1 | 0.0244227 |
| OGA | O-GlcNAcase | 0.0243918 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.024385 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0243082 |
| BPTF | bromodomain PHD finger transcription factor | 0.024298 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0242417 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0239903 |
| NOP58 | NOP58 ribonucleoprotein | 0.0239562 |
| CD46 | CD46 molecule, complement regulatory protein | 0.023825 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0237858 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0237835 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0237267 |
| ATRNL1 | attractin-like 1 | 0.0236949 |
| GOLGA4 | golgin A4 | 0.0236066 |
| HAND2 | heart and neural crest derivatives expressed 2 | 0.0235616 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0233817 |
| PHF3 | PHD finger protein 3 | 0.0232864 |
| WBP11 | WW domain binding protein 11 | 0.0232121 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0231421 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0229878 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.022791 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0226153 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.30678 |
| VCL | vinculin | -0.197685 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.16166 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.118035 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.113629 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0823879 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0820854 |
| NRG1 | neuregulin 1 | -0.0804936 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0728134 |
| PLAT | plasminogen activator, tissue | -0.0634034 |
| ACTG1 | actin gamma 1 | -0.0623424 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0569501 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0559136 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0540847 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0529495 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0528751 |
| TLE4 | transducin-like enhancer of split 4 | -0.0528587 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0527144 |
| PRKCA | protein kinase C, alpha | -0.0515589 |
| DTNA | dystrobrevin, alpha | -0.0492778 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0467072 |
| INTS6 | integrator complex subunit 6 | -0.0459052 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0456921 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0431602 |
| MED13 | mediator complex subunit 13 | -0.0424687 |
| THBS1 | thrombospondin 1 | -0.0418884 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0412614 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0407027 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.040576 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0400654 |
| FERMT2 | fermitin family member 2 | -0.038242 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0376998 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367514 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0364432 |
| EGR1 | early growth response 1 | -0.036245 |
| CDH13 | cadherin 13 | -0.0354528 |
| PTK2 | protein tyrosine kinase 2 | -0.0352733 |
| TPM1 | tropomyosin 1 (alpha) | -0.0349213 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0343563 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0333627 |
| RPL38 | ribosomal protein L38 | -0.0329258 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0320456 |
| TRIB2 | tribbles pseudokinase 2 | -0.0320151 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0319901 |
| PCBP2 | poly(rC) binding protein 2 | -0.0316714 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0312848 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0312614 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0310825 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0309867 |
| CRH | corticotropin releasing hormone | -0.030816 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0302408 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0302114 |
| EP300 | E1A binding protein p300 | -0.0301978 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.029301 |
| MYO1E | myosin IE | -0.0292866 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.029188 |
| ZNF638 | zinc finger protein 638 | -0.0288828 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0288743 |
| HMGA2 | high mobility group AT-hook 2 | -0.0282205 |
| RCOR1 | REST corepressor 1 | -0.0280091 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0277652 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0275239 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0270274 |
| TPM4 | tropomyosin 4 | -0.0270061 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0269217 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0267373 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0266275 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0262834 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0262736 |
| ACTN1 | actinin, alpha 1 | -0.0258868 |
| SEPTIN7 | septin 7 | -0.0258561 |
| CADM1 | cell adhesion molecule 1 | -0.0256918 |
| ACLY | ATP citrate lyase | -0.0255819 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0252265 |
| AK1 | adenylate kinase 1 | -0.0250605 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0250005 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0249214 |
| LUC7L | LUC7-like (S. cerevisiae) | -0.0249102 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0247992 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | -0.0246596 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0244028 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.0243773 |
| FRYL | FRY-like | -0.0241074 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0241033 |
| HDLBP | high density lipoprotein binding protein | -0.024048 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0239811 |
| RBM25 | RNA binding motif protein 25 | -0.0239649 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0238498 |
| DIPK2A | divergent protein kinase domain 2A | -0.0237788 |
| POTEF | POTE ankyrin domain family, member F | -0.0236896 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0236893 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0236826 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0235043 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0234782 |
| STC1 | stanniocalcin 1 | -0.0232239 |
| PMP22 | peripheral myelin protein 22 | -0.0232022 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0229981 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0228703 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0227941 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0227796 |
