| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the olaparib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.209146 |
| CLU | clusterin | 0.135934 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.113797 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.110643 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.109215 |
| ITGA6 | integrin, alpha 6 | 0.104567 |
| MEF2A | myocyte enhancer factor 2A | 0.100623 |
| BCL2L1 | BCL2-like 1 | 0.0872917 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0869615 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0854196 |
| NDRG1 | N-myc downstream regulated 1 | 0.0830903 |
| KRT17 | keratin 17, type I | 0.0822969 |
| PTMA | prothymosin, alpha | 0.0819996 |
| PRELID2 | PRELI domain containing 2 | 0.0795605 |
| OGA | O-GlcNAcase | 0.0774096 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0752734 |
| CUL4B | cullin 4B | 0.0750412 |
| FOXO1 | forkhead box O1 | 0.0750141 |
| EMP1 | epithelial membrane protein 1 | 0.0730169 |
| RBM39 | RNA binding motif protein 39 | 0.0720762 |
| PLAT | plasminogen activator, tissue | 0.0714204 |
| B2M | beta-2-microglobulin | 0.0639982 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0609333 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0608033 |
| KIAA1217 | KIAA1217 | 0.0590264 |
| ARRDC3 | arrestin domain containing 3 | 0.0588386 |
| ANLN | anillin, actin binding protein | 0.0574634 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0563189 |
| FOXP1 | forkhead box P1 | 0.0560738 |
| NEK7 | NIMA-related kinase 7 | 0.0550745 |
| MYOF | myoferlin | 0.0541372 |
| NRG1 | neuregulin 1 | 0.0534737 |
| YBX3 | Y box binding protein 3 | 0.0526536 |
| SERINC3 | serine incorporator 3 | 0.0522921 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0519902 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0518938 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0518886 |
| SULF1 | sulfatase 1 | 0.0518785 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0518768 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0500157 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0497688 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0485632 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0484835 |
| AHNAK | AHNAK nucleoprotein | 0.0482161 |
| RIN2 | Ras and Rab interactor 2 | 0.0477607 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.047727 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0465874 |
| EZR | ezrin | 0.0465739 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0443585 |
| ASPH | aspartate beta-hydroxylase | 0.0439878 |
| METTL15 | methyltransferase like 15 | 0.0439713 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0437836 |
| BLCAP | bladder cancer associated protein | 0.0437642 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0421664 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421169 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0421079 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0418212 |
| GOLGA4 | golgin A4 | 0.0416784 |
| EHF | ets homologous factor | 0.0415737 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0413323 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0412486 |
| SLC45A4 | solute carrier family 45, member 4 | 0.0403658 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0400703 |
| TMSB4X | thymosin beta 4, X-linked | 0.0400271 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0394889 |
| CD99 | CD99 molecule | 0.0392013 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.0389431 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.038013 |
| ANXA2 | annexin A2 | 0.0377537 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0375156 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0374083 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0372121 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0366416 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0364459 |
| RNF19B | ring finger protein 19B | 0.0362535 |
| LMNA | lamin A/C | 0.036073 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0358185 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0354835 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0349066 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0349043 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0346524 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0345617 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0343343 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0343268 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0340003 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0339179 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0337331 |
| CALU | calumenin | 0.0335128 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.033261 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0332314 |
| ENO1 | enolase 1, (alpha) | 0.0331692 |
| SDC4 | syndecan 4 | 0.0331282 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0330417 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0324838 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0323415 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0322508 |
| LIMA1 | LIM domain and actin binding 1 | 0.0311239 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.031037 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0307366 |
| TMSB10 | thymosin beta 10 | 0.0307177 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.119516 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.105635 |
| LMO7 | LIM domain 7 | -0.100591 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0978616 |
| INTS6 | integrator complex subunit 6 | -0.0894529 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0840987 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0823764 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0785873 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0768472 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0730207 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0722053 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0628457 |
| HMGA2 | high mobility group AT-hook 2 | -0.0624952 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0615742 |
| POTEF | POTE ankyrin domain family, member F | -0.0602881 |
| SULF2 | sulfatase 2 | -0.0596333 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0594466 |
| RASAL2 | RAS protein activator like 2 | -0.0560547 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0554823 |
| MTSS1 | metastasis suppressor 1 | -0.0535918 |
| PLS3 | plastin 3 | -0.053315 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0509005 |
| LAMA5 | laminin, alpha 5 | -0.0506411 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0501714 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.04986 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0480366 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0473922 |
| EGR1 | early growth response 1 | -0.0468187 |
| RAI14 | retinoic acid induced 14 | -0.0425957 |
| NAV2 | neuron navigator 2 | -0.0425707 |
| CDK6 | cyclin-dependent kinase 6 | -0.0393698 |
| SQSTM1 | sequestosome 1 | -0.0391407 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.038121 |
| PRSS23 | protease, serine, 23 | -0.0381071 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0362526 |
| RIGI | RNA sensor RIG-I | -0.0355442 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.034991 |
| RAB7A | RAB7A, member RAS oncogene family | -0.034076 |
| CALB1 | calbindin 1, 28kDa | -0.0334635 |
| ACTG1 | actin gamma 1 | -0.0321348 |
| ABLIM3 | actin binding LIM protein family, member 3 | -0.0320233 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0319527 |
| UTRN | utrophin | -0.0317784 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0314525 |
| CUX1 | cut-like homeobox 1 | -0.0312091 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0308268 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0299315 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0295872 |
| CSTB | cystatin B (stefin B) | -0.0295681 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0294929 |
| EGFR | epidermal growth factor receptor | -0.0294792 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0294713 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0292041 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0288934 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0288661 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0285103 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0282796 |
| FTL | ferritin, light polypeptide | -0.0277871 |
| FBXO11 | F-box protein 11 | -0.0274188 |
| ITGB4 | integrin, beta 4 | -0.0266318 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.026206 |
| COL5A1 | collagen, type V, alpha 1 | -0.026204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0259568 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0258506 |
| RAD51B | RAD51 paralog B | -0.02544 |
| KIAA1671 | KIAA1671 | -0.0250023 |
| RNF217 | ring finger protein 217 | -0.0247963 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0246512 |
| ECE1 | endothelin converting enzyme 1 | -0.0246233 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0245723 |
| FLNA | filamin A, alpha | -0.0242902 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.024091 |
| UBAP2 | ubiquitin associated protein 2 | -0.0240464 |
| PCDH1 | protocadherin 1 | -0.0239579 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0235017 |
| LAMC2 | laminin, gamma 2 | -0.0234585 |
| HMGA1 | high mobility group AT-hook 1 | -0.0232827 |
| RUNX1 | runt-related transcription factor 1 | -0.0232729 |
| FRMD4B | FERM domain containing 4B | -0.0232187 |
| ACTN1 | actinin, alpha 1 | -0.0231075 |
| RCOR1 | REST corepressor 1 | -0.0228637 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0227311 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0226325 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0222939 |
| EFNA5 | ephrin-A5 | -0.0222326 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0220375 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0219959 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0219322 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0214412 |
| ACTN4 | actinin, alpha 4 | -0.0214126 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0211331 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.0210789 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0210095 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0208924 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0207319 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0206947 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0206812 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0205288 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.0205076 |
| KIAA1549L | KIAA1549-like | -0.0202965 |
