| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.132326 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.119273 |
| FAM13A | family with sequence similarity 13, member A | 0.108747 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103467 |
| GOLGA4 | golgin A4 | 0.100339 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.099375 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0738802 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0722823 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0642759 |
| OGA | O-GlcNAcase | 0.0587817 |
| EREG | epiregulin | 0.0562774 |
| NDRG1 | N-myc downstream regulated 1 | 0.0553762 |
| VEGFA | vascular endothelial growth factor A | 0.0536886 |
| RNF145 | ring finger protein 145 | 0.0527209 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0515088 |
| RBM39 | RNA binding motif protein 39 | 0.0489546 |
| RNF43 | ring finger protein 43 | 0.0477671 |
| FNBP1L | formin binding protein 1-like | 0.046462 |
| TXNIP | thioredoxin interacting protein | 0.0451463 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0433731 |
| MED13L | mediator complex subunit 13-like | 0.0421932 |
| PRELID2 | PRELI domain containing 2 | 0.0409749 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0406372 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.040232 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0397076 |
| KRT8 | keratin 8, type II | 0.0390328 |
| EXOC1 | exocyst complex component 1 | 0.0389689 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0386153 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0382642 |
| CALR | calreticulin | 0.0375153 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0375035 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0374931 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0373301 |
| NFIA | nuclear factor I/A | 0.0371496 |
| YBX1 | Y box binding protein 1 | 0.0370996 |
| TMF1 | TATA element modulatory factor 1 | 0.0370856 |
| SETD5 | SET domain containing 5 | 0.0370784 |
| NBAS | neuroblastoma amplified sequence | 0.036919 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0367505 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0367093 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.036675 |
| GOLGB1 | golgin B1 | 0.0358326 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0358115 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0350264 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0349037 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0347506 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0346877 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0341335 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0331943 |
| ITGA6 | integrin, alpha 6 | 0.0328687 |
| ZNF292 | zinc finger protein 292 | 0.032754 |
| TXNRD1 | thioredoxin reductase 1 | 0.0326841 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0322611 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0319144 |
| WDR45B | WD repeat domain 45B | 0.0315118 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0314173 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0309489 |
| SRP54 | signal recognition particle 54kDa | 0.0309487 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0306339 |
| CCNY | cyclin Y | 0.030607 |
| YME1L1 | YME1-like 1 ATPase | 0.0304676 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0302891 |
| KITLG | KIT ligand | 0.0302365 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | 0.0300809 |
| KIF5B | kinesin family member 5B | 0.0297799 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0297634 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0297422 |
| RPS6 | ribosomal protein S6 | 0.0295484 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0291134 |
| RRBP1 | ribosome binding protein 1 | 0.0291068 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0288218 |
| CENPF | centromere protein F, 350/400kDa | 0.0287338 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0285606 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0281927 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0281725 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0281596 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0281586 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0280546 |
| MATR3 | matrin 3 | 0.0279468 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0279046 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0278305 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0278176 |
| COG5 | component of oligomeric golgi complex 5 | 0.0275822 |
| YTHDC1 | YTH domain containing 1 | 0.0275419 |
| COPA | coatomer protein complex, subunit alpha | 0.0275283 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0274723 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0273671 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0271703 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0268148 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0266803 |
| CTBP2 | C-terminal binding protein 2 | 0.0264736 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0261736 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0261446 |
| ADD3 | adducin 3 (gamma) | 0.0260508 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0257116 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0256125 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0255148 |
| RPS12 | ribosomal protein S12 | 0.0252908 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0251962 |
| PTEN | phosphatase and tensin homolog | 0.0250985 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.107316 |
| VCL | vinculin | -0.0967432 |
| MYO1E | myosin IE | -0.0888508 |
| FAT1 | FAT atypical cadherin 1 | -0.0876311 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0876218 |
| NPSR1 | neuropeptide S receptor 1 | -0.0820207 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0797151 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0785147 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0682952 |
| ANTXR2 | anthrax toxin receptor 2 | -0.066921 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0658913 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0598134 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0597169 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0593724 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0591711 |
| LAMA4 | laminin, alpha 4 | -0.0586345 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0569426 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0569193 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0513963 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0508754 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0499806 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0479528 |
| ONECUT3 | one cut homeobox 3 | -0.0477207 |
| EGFR | epidermal growth factor receptor | -0.0436741 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0424309 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0410779 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0395099 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.038884 |
| ACTG1 | actin gamma 1 | -0.038515 |
| MUC17 | mucin 17, cell surface associated | -0.0384221 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0381784 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0379229 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0374065 |
| SVIL | supervillin | -0.0364747 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.036081 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0357329 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0348435 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0346169 |
| ASPH | aspartate beta-hydroxylase | -0.0344244 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0342098 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0339377 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0333619 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0332641 |
| FHIT | fragile histidine triad | -0.033242 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0329079 |
| POTEF | POTE ankyrin domain family, member F | -0.0328794 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0325928 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0322083 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0316455 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0314117 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0305853 |
| POF1B | premature ovarian failure, 1B | -0.0300864 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.02936 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0286407 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0280458 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0273295 |
| H1-0 | H1.0 linker histone | -0.0269584 |
| RAD51B | RAD51 paralog B | -0.0269197 |
| CCND1 | cyclin D1 | -0.0268905 |
| TPM1 | tropomyosin 1 (alpha) | -0.0267277 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0264718 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0260609 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0260431 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0256749 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0256599 |
| ACTN4 | actinin, alpha 4 | -0.0252379 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0251369 |
| PALLD | palladin, cytoskeletal associated protein | -0.0250235 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0247489 |
| TNS4 | tensin 4 | -0.0247329 |
| EGR1 | early growth response 1 | -0.0243302 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0243177 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0242432 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0241016 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.024063 |
| PCDH9 | protocadherin 9 | -0.0238061 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0237928 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0235592 |
| FOSL1 | FOS-like antigen 1 | -0.0235525 |
| INTS6 | integrator complex subunit 6 | -0.0232872 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0232511 |
| SIK3 | SIK family kinase 3 | -0.0230375 |
| USP53 | ubiquitin specific peptidase 53 | -0.0229681 |
| SMYD3 | SET and MYND domain containing 3 | -0.0229338 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | -0.0228906 |
| PARD3 | par-3 family cell polarity regulator | -0.022846 |
| HMGA1 | high mobility group AT-hook 1 | -0.0225135 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0224638 |
| DIAPH1 | diaphanous-related formin 1 | -0.0222124 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.021951 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0219267 |
| TRIB1 | tribbles pseudokinase 1 | -0.021811 |
| ABR | active BCR-related | -0.0214135 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0213567 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0210076 |
| RPLP0 | ribosomal protein, large, P0 | -0.0208477 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0206961 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0205022 |
| FBXO11 | F-box protein 11 | -0.0203465 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0202435 |
