| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.12544 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0701667 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.067559 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0658437 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0656743 |
| LAMC2 | laminin, gamma 2 | 0.0632941 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.061892 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0616769 |
| MKI67 | marker of proliferation Ki-67 | 0.0594315 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0569625 |
| FAM13A | family with sequence similarity 13, member A | 0.0541398 |
| OSMR | oncostatin M receptor | 0.0540467 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0479733 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0472582 |
| ARRDC3 | arrestin domain containing 3 | 0.0448628 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0440857 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0409902 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0401696 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0398342 |
| CES1 | carboxylesterase 1 | 0.0396872 |
| LMO7 | LIM domain 7 | 0.0393969 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0391184 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0373184 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0367697 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0355473 |
| NGLY1 | N-glycanase 1 | 0.0343302 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0342275 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0338636 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0334867 |
| EFNA5 | ephrin-A5 | 0.0331906 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0324932 |
| DSPP | dentin sialophosphoprotein | 0.0324275 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0309867 |
| PTEN | phosphatase and tensin homolog | 0.0304766 |
| FRY | furry homolog (Drosophila) | 0.0294368 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0291464 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0290787 |
| ZNF292 | zinc finger protein 292 | 0.0281842 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0281117 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0279432 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0277491 |
| CENPF | centromere protein F, 350/400kDa | 0.0273421 |
| GOLGB1 | golgin B1 | 0.0272437 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0267496 |
| MGAT4C | MGAT4 family, member C | 0.0265543 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0262619 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0248626 |
| RNF149 | ring finger protein 149 | 0.0248601 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0247019 |
| MGST1 | microsomal glutathione S-transferase 1 | 0.0246152 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0245859 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0243636 |
| TMF1 | TATA element modulatory factor 1 | 0.0239711 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0234787 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0232767 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0230158 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0230093 |
| TMEM45B | transmembrane protein 45B | 0.0226716 |
| PRELID2 | PRELI domain containing 2 | 0.0225443 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0223849 |
| VEGFA | vascular endothelial growth factor A | 0.0221361 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0220789 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0219931 |
| WDR26 | WD repeat domain 26 | 0.021452 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0211133 |
| MCL1 | myeloid cell leukemia 1 | 0.0210973 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0209231 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0207595 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0207447 |
| ALPK1 | alpha-kinase 1 | 0.0207008 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0206361 |
| TBC1D22A | TBC1 domain family, member 22A | 0.020629 |
| SP3 | Sp3 transcription factor | 0.0205438 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0205159 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0204811 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0203854 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0201636 |
| PHF21A | PHD finger protein 21A | 0.0199757 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0198382 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0197762 |
| N4BP2 | NEDD4 binding protein 2 | 0.0196787 |
| METTL15 | methyltransferase like 15 | 0.0196532 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0195846 |
| ANO6 | anoctamin 6 | 0.0191018 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0190848 |
| RTN4 | reticulon 4 | 0.0190754 |
| UBAC2 | UBA domain containing 2 | 0.0190726 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0190529 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.019011 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0189363 |
| TBL1X | transducin (beta)-like 1X-linked | 0.018898 |
| MPZL3 | myelin protein zero-like 3 | 0.0188858 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0187468 |
| KDM5A | lysine (K)-specific demethylase 5A | 0.0187376 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0187269 |
| ZNF148 | zinc finger protein 148 | 0.0186785 |
| CTTN | cortactin | 0.0186376 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0185551 |
| COPA | coatomer protein complex, subunit alpha | 0.0185383 |
| FNIP1 | folliculin interacting protein 1 | 0.0183085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.382898 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.134139 |
| LOC112694756 | uncharaterized LOC112694756 | -0.106755 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0938096 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0933168 |
| H1-0 | H1.0 linker histone | -0.0896482 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0828796 |
| FTL | ferritin, light polypeptide | -0.076111 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0731138 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0677006 |
| RPLP1 | ribosomal protein, large, P1 | -0.0669352 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0657098 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0634107 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0633823 |
| MYOF | myoferlin | -0.0632165 |
| MT2A | metallothionein 2A | -0.0601471 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0574437 |
| EGR1 | early growth response 1 | -0.0568145 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0549423 |
| TMSB10 | thymosin beta 10 | -0.0545724 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0541114 |
| EGFR | epidermal growth factor receptor | -0.0518519 |
| ANXA2 | annexin A2 | -0.0498566 |
| HOMER1 | homer scaffolding protein 1 | -0.0496601 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0494911 |
| NABP1 | nucleic acid binding protein 1 | -0.0458013 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.045637 |
| RPLP0 | ribosomal protein, large, P0 | -0.0453132 |
| INTS6 | integrator complex subunit 6 | -0.0430216 |
| ACTG1 | actin gamma 1 | -0.0425861 |
| GRAMD1B | GRAM domain containing 1B | -0.0408225 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0395721 |
| MORF4L2 | mortality factor 4 like 2 | -0.0393035 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0352942 |
| WASF2 | WAS protein family, member 2 | -0.035247 |
| HDLBP | high density lipoprotein binding protein | -0.0350161 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.034837 |
| RPL35A | ribosomal protein L35a | -0.0344662 |
| RPS3 | ribosomal protein S3 | -0.0342085 |
| SPAG9 | sperm associated antigen 9 | -0.0339934 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0334791 |
| RPS25 | ribosomal protein S25 | -0.0334505 |
| RACK1 | receptor for activated C kinase 1 | -0.0334375 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0329854 |
| UVRAG | UV radiation resistance associated | -0.0326675 |
| SEC61G | Sec61 gamma subunit | -0.0320334 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0320287 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0314397 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0313312 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0312612 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0309391 |
| ARF1 | ADP-ribosylation factor 1 | -0.0301689 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0299122 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0294915 |
| RPS24 | ribosomal protein S24 | -0.0292491 |
| TOP1 | topoisomerase (DNA) I | -0.0289579 |
| HBP1 | HMG-box transcription factor 1 | -0.0288836 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0286393 |
| ENO1 | enolase 1, (alpha) | -0.0285614 |
| ABLIM1 | actin binding LIM protein 1 | -0.0282934 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.027979 |
| CSNK1E | casein kinase 1, epsilon | -0.0277784 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0276538 |
| MYO1E | myosin IE | -0.0274626 |
| GM2A | GM2 ganglioside activator | -0.0271156 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0264807 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.0261323 |
| SMAD3 | SMAD family member 3 | -0.0260109 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0250282 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.024879 |
| IER3 | immediate early response 3 | -0.0248296 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246434 |
| SMYD3 | SET and MYND domain containing 3 | -0.0245973 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0245887 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0245564 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0240557 |
| RPS8 | ribosomal protein S8 | -0.0239936 |
| MAP7 | microtubule-associated protein 7 | -0.023983 |
| RUNX1 | runt-related transcription factor 1 | -0.0238063 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0237611 |
| RPL8 | ribosomal protein L8 | -0.0236826 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0233586 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.023308 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0232719 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.023089 |
| PER1 | period circadian clock 1 | -0.0229992 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0228584 |
| CCND1 | cyclin D1 | -0.0228007 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0227836 |
| MT1X | metallothionein 1X | -0.0227385 |
| FLNA | filamin A, alpha | -0.0226912 |
| SEC24A | SEC24 family member A | -0.0226323 |
| EMP1 | epithelial membrane protein 1 | -0.0226111 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0225679 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0225088 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0224446 |
| LDHA | lactate dehydrogenase A | -0.0219185 |
| CSTB | cystatin B (stefin B) | -0.0218185 |
| CMIP | c-Maf inducing protein | -0.0217366 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0215574 |
