| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the olaparib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0566084 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0468061 |
| VEGFA | vascular endothelial growth factor A | 0.0359658 |
| FAM13A | family with sequence similarity 13, member A | 0.031733 |
| RPS6 | ribosomal protein S6 | 0.0212685 |
| KYNU | kynureninase | 0.020592 |
| RNF145 | ring finger protein 145 | 0.0194314 |
| RPL37A | ribosomal protein L37a | 0.0164398 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0161923 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0160517 |
| SETD5 | SET domain containing 5 | 0.0150515 |
| FTL | ferritin, light polypeptide | 0.0149086 |
| RPL36 | ribosomal protein L36 | 0.0148548 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0138713 |
| RPS12 | ribosomal protein S12 | 0.0137307 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0135457 |
| RUNX2 | runt-related transcription factor 2 | 0.0133828 |
| RPS27 | ribosomal protein S27 | 0.0132576 |
| RPS3 | ribosomal protein S3 | 0.0130515 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0125821 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0125815 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0123348 |
| ARRDC3 | arrestin domain containing 3 | 0.0123064 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.012109 |
| RPL31 | ribosomal protein L31 | 0.0120033 |
| SNX13 | sorting nexin 13 | 0.0115121 |
| RPL7A | ribosomal protein L7a | 0.0114685 |
| LRRC49 | leucine rich repeat containing 49 | 0.0113033 |
| RPS29 | ribosomal protein S29 | 0.0111989 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0109901 |
| GPC6 | glypican 6 | 0.010952 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.010944 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0108307 |
| TGFB2 | transforming growth factor, beta 2 | 0.0108021 |
| FBXO32 | F-box protein 32 | 0.010773 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0105563 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0102887 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0100518 |
| RPL28 | ribosomal protein L28 | 0.0100228 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00987585 |
| JMY | junction mediating and regulatory protein, p53 cofactor | 0.00981411 |
| TMEM165 | transmembrane protein 165 | 0.00977199 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.00973805 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.00971881 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.00971439 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00956267 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.00938577 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00937422 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.00931615 |
| ZNF292 | zinc finger protein 292 | 0.00931179 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0091036 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00897734 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00892816 |
| ALPK1 | alpha-kinase 1 | 0.00890755 |
| RPS8 | ribosomal protein S8 | 0.0088566 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0088507 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00881044 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.00876382 |
| SUCO | SUN domain containing ossification factor | 0.00868234 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00862963 |
| RPS2 | ribosomal protein S2 | 0.00862712 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.00850792 |
| PTEN | phosphatase and tensin homolog | 0.00840358 |
| RPS10 | ribosomal protein S10 | 0.00839981 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00834015 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.00826981 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.008125 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0081205 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0081033 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00802572 |
| TUBE1 | tubulin, epsilon 1 | 0.00801262 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.00799909 |
| PNN | pinin, desmosome associated protein | 0.00797448 |
| TOB2 | transducer of ERBB2, 2 | 0.00790878 |
| CENPF | centromere protein F, 350/400kDa | 0.00790454 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.00790279 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00789995 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00787045 |
| PCM1 | pericentriolar material 1 | 0.00785588 |
| CCNL1 | cyclin L1 | 0.00780493 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.00778135 |
| ZNF395 | zinc finger protein 395 | 0.0076959 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.00761026 |
| CFB | complement factor B | 0.00760336 |
| RPS13 | ribosomal protein S13 | 0.00749458 |
| PRELID2 | PRELI domain containing 2 | 0.00746569 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.00744583 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00743901 |
| RAB27A | RAB27A, member RAS oncogene family | 0.00738322 |
| MORF4L2 | mortality factor 4 like 2 | 0.0073796 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.00737154 |
| NNMT | nicotinamide N-methyltransferase | 0.00734906 |
| DTX3 | deltex 3, E3 ubiquitin ligase | 0.00734318 |
| YY1AP1 | YY1 associated protein 1 | 0.00729498 |
| COL5A2 | collagen, type V, alpha 2 | 0.00722173 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00720287 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00718078 |
| DIPK1A | divergent protein kinase domain 1A | 0.00715033 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00714726 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | 0.00714187 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.183671 |
| VIM | vimentin | -0.175285 |
| LOX | lysyl oxidase | -0.14988 |
| FN1 | fibronectin 1 | -0.13408 |
| HMGA2 | high mobility group AT-hook 2 | -0.123711 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.12265 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11217 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.111795 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.103701 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.103587 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.100145 |
| TMSB10 | thymosin beta 10 | -0.0984184 |
| STC1 | stanniocalcin 1 | -0.0964798 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0960312 |
| CDH13 | cadherin 13 | -0.0917445 |
| PCBP2 | poly(rC) binding protein 2 | -0.0895966 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0815753 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0797859 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0782406 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0758089 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0744111 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0734864 |
| AHNAK | AHNAK nucleoprotein | -0.0706859 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0698946 |
| EFNA5 | ephrin-A5 | -0.0673491 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0657989 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0648569 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0626873 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0625321 |
| FAM20C | family with sequence similarity 20, member C | -0.0564861 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.055807 |
| UBC | ubiquitin C | -0.0556737 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0545705 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0543292 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.054019 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0539659 |
| ENO1 | enolase 1, (alpha) | -0.053483 |
| MT2A | metallothionein 2A | -0.0527838 |
| MTSS1 | metastasis suppressor 1 | -0.0520292 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0508145 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0506742 |
| GLCCI1 | glucocorticoid induced 1 | -0.0502688 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0496845 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0487437 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.048715 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0485013 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0481957 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0478969 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0475244 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0468174 |
| ASPH | aspartate beta-hydroxylase | -0.046571 |
| TMSB4X | thymosin beta 4, X-linked | -0.0462016 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0458952 |
| NRP1 | neuropilin 1 | -0.0447319 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0441895 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0429247 |
| USP34 | ubiquitin specific peptidase 34 | -0.042516 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0422712 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0422194 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0416502 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0411435 |
| S100A6 | S100 calcium binding protein A6 | -0.0407647 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0406604 |
| SMAD3 | SMAD family member 3 | -0.0404316 |
| MYO10 | myosin X | -0.0403944 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0400288 |
| CDCP1 | CUB domain containing protein 1 | -0.0397271 |
| MAP1B | microtubule-associated protein 1B | -0.0391835 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0384626 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0380663 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0379838 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0378946 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0377498 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0375763 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0375288 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0369186 |
| EMP1 | epithelial membrane protein 1 | -0.0365903 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0362471 |
| FAM107B | family with sequence similarity 107, member B | -0.0360052 |
| ATXN1 | ataxin 1 | -0.0357059 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0353236 |
| RAB27B | RAB27B, member RAS oncogene family | -0.035301 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0351754 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0350721 |
| FLNB | filamin B, beta | -0.0348841 |
| AADAC | arylacetamide deacetylase | -0.034883 |
| TGM2 | transglutaminase 2 | -0.0346351 |
| ECE1 | endothelin converting enzyme 1 | -0.0343779 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0339206 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0338712 |
| NAV2 | neuron navigator 2 | -0.0338047 |
| SEPTIN9 | septin 9 | -0.0336605 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0332728 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0327449 |
| CALR | calreticulin | -0.0325324 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0320429 |
| NRG1 | neuregulin 1 | -0.0319948 |
| SP100 | SP100 nuclear antigen | -0.0319854 |
| IL6ST | interleukin 6 signal transducer | -0.031962 |
| HPCAL1 | hippocalcin-like 1 | -0.0317015 |
