| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0983663 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0774138 |
| PRELID2 | PRELI domain containing 2 | 0.0634006 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0590813 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0542243 |
| TXNRD1 | thioredoxin reductase 1 | 0.0492887 |
| RBM39 | RNA binding motif protein 39 | 0.0473415 |
| ZNF292 | zinc finger protein 292 | 0.0431086 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0422119 |
| GOLGA4 | golgin A4 | 0.0421851 |
| FLNB | filamin B, beta | 0.0417084 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0406699 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0405087 |
| EZR | ezrin | 0.0403719 |
| CCNL1 | cyclin L1 | 0.0387818 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0376055 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0369431 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0365118 |
| ANK2 | ankyrin 2, neuronal | 0.0351443 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341 |
| OGA | O-GlcNAcase | 0.0335939 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0335846 |
| RNF145 | ring finger protein 145 | 0.0334312 |
| RPL3 | ribosomal protein L3 | 0.0328609 |
| ZNF608 | zinc finger protein 608 | 0.032782 |
| NCKAP1 | NCK-associated protein 1 | 0.0325064 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.032276 |
| GSK3B | glycogen synthase kinase 3 beta | 0.032068 |
| PYGB | phosphorylase, glycogen; brain | 0.0319101 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314909 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0309554 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0305469 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0298673 |
| CDC73 | cell division cycle 73 | 0.0294096 |
| RTN4 | reticulon 4 | 0.0288198 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0285694 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0279554 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0274192 |
| NBAS | neuroblastoma amplified sequence | 0.0273339 |
| YEATS2 | YEATS domain containing 2 | 0.0273105 |
| METTL15 | methyltransferase like 15 | 0.0272947 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0271637 |
| PLPP3 | phospholipid phosphatase 3 | 0.0271094 |
| VMP1 | vacuole membrane protein 1 | 0.0270011 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0269296 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0267709 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0264854 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0264053 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0262023 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0261916 |
| FAM13A | family with sequence similarity 13, member A | 0.0261095 |
| TMEM65 | transmembrane protein 65 | 0.0260449 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0259909 |
| COG5 | component of oligomeric golgi complex 5 | 0.0249867 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.024807 |
| ARRDC3 | arrestin domain containing 3 | 0.0247072 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0246122 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0240644 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.023886 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0233866 |
| TFG | TRK-fused gene | 0.0233687 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0228061 |
| TPD52 | tumor protein D52 | 0.0226851 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0226378 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0224638 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0224075 |
| TMF1 | TATA element modulatory factor 1 | 0.0222037 |
| XPO1 | exportin 1 | 0.022148 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0220794 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0219121 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0215975 |
| RBM25 | RNA binding motif protein 25 | 0.0214261 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0213815 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0213278 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0212693 |
| PDGFC | platelet derived growth factor C | 0.0211746 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0211547 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0211228 |
| HDAC9 | histone deacetylase 9 | 0.0210112 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0209214 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0208928 |
| DENND4A | DENN/MADD domain containing 4A | 0.0204471 |
| YTHDC1 | YTH domain containing 1 | 0.0204268 |
| CDK19 | cyclin-dependent kinase 19 | 0.0203713 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0201794 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0200552 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0200495 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.020027 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.019974 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0198826 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0196985 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.019691 |
| QKI | QKI, KH domain containing, RNA binding | 0.0195677 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0195636 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0193625 |
| MED13L | mediator complex subunit 13-like | 0.0192528 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0192189 |
| PTK2 | protein tyrosine kinase 2 | 0.0191695 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0191278 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0189423 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.217775 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.141897 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.141494 |
| PTMA | prothymosin, alpha | -0.137924 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.111426 |
| FOXP1 | forkhead box P1 | -0.111315 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.1058 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105731 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.10486 |
| BMP10 | bone morphogenetic protein 10 | -0.0977702 |
| ACTG1 | actin gamma 1 | -0.0897301 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0755936 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0710956 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0621052 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0522995 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0513758 |
| CCND1 | cyclin D1 | -0.0490192 |
| RPS8 | ribosomal protein S8 | -0.0488968 |
| RPL35A | ribosomal protein L35a | -0.0488332 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0461395 |
| RPLP1 | ribosomal protein, large, P1 | -0.0452701 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0447584 |
| RPL31 | ribosomal protein L31 | -0.0438522 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0434634 |
| GLI3 | GLI family zinc finger 3 | -0.0431471 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0420623 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0419718 |
| ENO1 | enolase 1, (alpha) | -0.0415187 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0412859 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0404799 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0392565 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0391281 |
| NBEA | neurobeachin | -0.0380868 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0378585 |
| VCL | vinculin | -0.0378054 |
| POTEF | POTE ankyrin domain family, member F | -0.0374532 |
| EGFR | epidermal growth factor receptor | -0.0372779 |
| DUSP4 | dual specificity phosphatase 4 | -0.0364441 |
| RPS6 | ribosomal protein S6 | -0.0358636 |
| RPLP0 | ribosomal protein, large, P0 | -0.0353986 |
| S100A6 | S100 calcium binding protein A6 | -0.0349013 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0345092 |
| S100A4 | S100 calcium binding protein A4 | -0.0343774 |
| TMSB4X | thymosin beta 4, X-linked | -0.0333117 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0330798 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0329021 |
| PDE7B | phosphodiesterase 7B | -0.0325451 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0318538 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0312757 |
| PFN1 | profilin 1 | -0.0311273 |
| LDHA | lactate dehydrogenase A | -0.030924 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0306814 |
| RPL12 | ribosomal protein L12 | -0.030446 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0295183 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0293253 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0287142 |
| FTL | ferritin, light polypeptide | -0.0285133 |
| CUX1 | cut-like homeobox 1 | -0.0281121 |
| RPS24 | ribosomal protein S24 | -0.0274472 |
| RPLP2 | ribosomal protein, large, P2 | -0.0273451 |
| RPS3 | ribosomal protein S3 | -0.0271703 |
| ONECUT2 | one cut homeobox 2 | -0.0269171 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0266585 |
| RPS13 | ribosomal protein S13 | -0.026447 |
| RPS25 | ribosomal protein S25 | -0.0264074 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0263953 |
| RPS23 | ribosomal protein S23 | -0.0263781 |
| SP100 | SP100 nuclear antigen | -0.0263627 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0263214 |
| RPL27A | ribosomal protein L27a | -0.0259975 |
| TJP1 | tight junction protein 1 | -0.0255811 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0254748 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0254271 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0254049 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0253808 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0248742 |
| RACK1 | receptor for activated C kinase 1 | -0.0248408 |
| ZNF438 | zinc finger protein 438 | -0.0247837 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0246404 |
| PGK1 | phosphoglycerate kinase 1 | -0.0246145 |
| PKM | pyruvate kinase, muscle | -0.0245428 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0243623 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0243292 |
| ANXA1 | annexin A1 | -0.0243017 |
| DUSP6 | dual specificity phosphatase 6 | -0.0240918 |
| RPL34 | ribosomal protein L34 | -0.0240424 |
| HMGB1 | high mobility group box 1 | -0.0238328 |
| TBCA | tubulin folding cofactor A | -0.0237949 |
| RPL19 | ribosomal protein L19 | -0.0236323 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0233546 |
| FER1L6 | fer-1-like family member 6 | -0.0233338 |
| RPL23 | ribosomal protein L23 | -0.023312 |
| MYO5C | myosin VC | -0.0231132 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.02307 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0228793 |
| RPL8 | ribosomal protein L8 | -0.0228411 |
| RPS16 | ribosomal protein S16 | -0.0224643 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0223423 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0222072 |
| MKI67 | marker of proliferation Ki-67 | -0.0219902 |
