| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.448295 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0888366 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0853447 |
| CADM1 | cell adhesion molecule 1 | 0.0804352 |
| KYNU | kynureninase | 0.0760412 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0651287 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0648958 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0631261 |
| DST | dystonin | 0.0605464 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0591661 |
| FBXO32 | F-box protein 32 | 0.0584719 |
| PRELID2 | PRELI domain containing 2 | 0.0577533 |
| RPS27A | ribosomal protein S27a | 0.055098 |
| RIGI | RNA sensor RIG-I | 0.0519027 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0501897 |
| RNF213 | ring finger protein 213 | 0.0499961 |
| MX1 | MX dynamin-like GTPase 1 | 0.0478438 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0477138 |
| TMSB10 | thymosin beta 10 | 0.0474728 |
| AHNAK | AHNAK nucleoprotein | 0.044307 |
| UBC | ubiquitin C | 0.0439512 |
| CFB | complement factor B | 0.0437281 |
| ATXN1 | ataxin 1 | 0.0436246 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0433381 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.039429 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0371954 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0371302 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0365019 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0356466 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0343729 |
| PCBP3 | poly(rC) binding protein 3 | 0.0343711 |
| TPM4 | tropomyosin 4 | 0.0329522 |
| VCL | vinculin | 0.0328968 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0324973 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0310041 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0307027 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0305285 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0296215 |
| XRN1 | 5'-3' exoribonuclease 1 | 0.0295669 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0292388 |
| PHF21A | PHD finger protein 21A | 0.0286806 |
| TNS3 | tensin 3 | 0.0283836 |
| HLA-B | major histocompatibility complex, class I, B | 0.0275235 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0274339 |
| PALLD | palladin, cytoskeletal associated protein | 0.0273841 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0268828 |
| ARRDC3 | arrestin domain containing 3 | 0.0264002 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0261987 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0261939 |
| GBP1 | guanylate binding protein 1, interferon-inducible | 0.026132 |
| THBS1 | thrombospondin 1 | 0.0259368 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | 0.0258776 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0250704 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0248924 |
| PLIN2 | perilipin 2 | 0.0248039 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0245665 |
| TRIM25 | tripartite motif containing 25 | 0.0241329 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0239538 |
| RPL37A | ribosomal protein L37a | 0.0237911 |
| PRKCSH | protein kinase C substrate 80K-H | 0.0237537 |
| RAD51B | RAD51 paralog B | 0.0236305 |
| HDAC8 | histone deacetylase 8 | 0.0236166 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0235626 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0235018 |
| NNMT | nicotinamide N-methyltransferase | 0.0230303 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.0228067 |
| MX2 | MX dynamin-like GTPase 2 | 0.0224832 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0224065 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0223993 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0221533 |
| CP | ceruloplasmin (ferroxidase) | 0.0220416 |
| GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.0219589 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0214864 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.0213827 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0212927 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0212237 |
| CDK19 | cyclin-dependent kinase 19 | 0.020802 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0207734 |
| METTL15 | methyltransferase like 15 | 0.0204049 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.0202883 |
| COL1A1 | collagen, type I, alpha 1 | 0.020152 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0201301 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0201022 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0199543 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.019843 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.019822 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0196638 |
| LRRC7 | leucine rich repeat containing 7 | 0.0196518 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0194996 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.0190769 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0188321 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0188071 |
| DENND2B | DENN domain containing 2B | 0.0187745 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0187192 |
| KLHL5 | kelch-like family member 5 | 0.0186717 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.018332 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0181365 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.018048 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0179166 |
| SP100 | SP100 nuclear antigen | 0.017733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.193452 |
| FN1 | fibronectin 1 | -0.183339 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.161253 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.136613 |
| STC1 | stanniocalcin 1 | -0.110168 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0992701 |
| HMGA2 | high mobility group AT-hook 2 | -0.0905345 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0889589 |
| SPAG9 | sperm associated antigen 9 | -0.0855548 |
| VCAN | versican | -0.0804642 |
| NAV2 | neuron navigator 2 | -0.0795526 |
| MT2A | metallothionein 2A | -0.0718394 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0699828 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0685838 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0677018 |
| ICAM1 | intercellular adhesion molecule 1 | -0.06431 |
| NDRG1 | N-myc downstream regulated 1 | -0.0639871 |
| RPS2 | ribosomal protein S2 | -0.0617669 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.059648 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0595713 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0589872 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0586311 |
| RPS6 | ribosomal protein S6 | -0.0568603 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0561751 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0550719 |
| CDH13 | cadherin 13 | -0.0525011 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0509765 |
| CDCP1 | CUB domain containing protein 1 | -0.050413 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0503753 |
| MSN | moesin | -0.0498726 |
| ADM | adrenomedullin | -0.0498403 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0490236 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0468527 |
| HMGA1 | high mobility group AT-hook 1 | -0.0448507 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0438169 |
| RPLP0 | ribosomal protein, large, P0 | -0.043495 |
| FMNL2 | formin-like 2 | -0.0431764 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0425967 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0425388 |
| TMSB4X | thymosin beta 4, X-linked | -0.0420802 |
| GLIS3 | GLIS family zinc finger 3 | -0.0413096 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0404273 |
| SYNJ2 | synaptojanin 2 | -0.0395144 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0391899 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0386773 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0383932 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0382289 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0379652 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0372904 |
| PGK1 | phosphoglycerate kinase 1 | -0.037227 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0371237 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0368944 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0362656 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0359806 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0357728 |
| LOX | lysyl oxidase | -0.0355873 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0355365 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.035186 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | -0.034832 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0346146 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0341596 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0335007 |
| SNX9 | sorting nexin 9 | -0.032694 |
| GOLGA4 | golgin A4 | -0.0326044 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0319946 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318562 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0318121 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0312072 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0310587 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0310468 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0306391 |
| EFNA5 | ephrin-A5 | -0.0303371 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0303238 |
| RASA2 | RAS p21 protein activator 2 | -0.0302128 |
| IER3 | immediate early response 3 | -0.0301054 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0296248 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0293943 |
| HDAC9 | histone deacetylase 9 | -0.0290798 |
| MORF4L2 | mortality factor 4 like 2 | -0.0290583 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0283226 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0283076 |
| LAMB1 | laminin, beta 1 | -0.0281067 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0279445 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0278484 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0276758 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027364 |
| NF1 | neurofibromin 1 | -0.0271121 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0269502 |
| PKM | pyruvate kinase, muscle | -0.0267172 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0266302 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0266068 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0263788 |
| WDR45B | WD repeat domain 45B | -0.0263487 |
| RLF | rearranged L-myc fusion | -0.0262476 |
| RUNX1 | runt-related transcription factor 1 | -0.0261934 |
| AFF4 | AF4/FMR2 family, member 4 | -0.026162 |
| MAP1B | microtubule-associated protein 1B | -0.0261234 |
| ZNF292 | zinc finger protein 292 | -0.0259405 |
| DENND4C | DENN/MADD domain containing 4C | -0.0258967 |
| SEPTIN7 | septin 7 | -0.0258836 |
