| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.107398 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0681677 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0624817 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.0601456 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.059376 |
| PRELID2 | PRELI domain containing 2 | 0.0513351 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0493678 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0476271 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0442349 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0429751 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0426398 |
| ARRDC3 | arrestin domain containing 3 | 0.0409317 |
| HDLBP | high density lipoprotein binding protein | 0.0396204 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0391827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0388513 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0384659 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0384314 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0370102 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0350672 |
| RABGAP1 | RAB GTPase activating protein 1 | 0.0349714 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0349202 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0336747 |
| COL5A2 | collagen, type V, alpha 2 | 0.0333964 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0332318 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0322981 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0320307 |
| DST | dystonin | 0.0300454 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.029608 |
| GSE1 | Gse1 coiled-coil protein | 0.0290703 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.02894 |
| HMGB2 | high mobility group box 2 | 0.0288731 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0287378 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0286375 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0280522 |
| LOXL2 | lysyl oxidase-like 2 | 0.0276309 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.026867 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0267294 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0267034 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0262497 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0262388 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0259741 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.025745 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0255528 |
| COL11A1 | collagen, type XI, alpha 1 | 0.025538 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.025383 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0253499 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0252311 |
| TMF1 | TATA element modulatory factor 1 | 0.0252059 |
| TMEM39A | transmembrane protein 39A | 0.0250359 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0249362 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0248945 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0248881 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.024874 |
| SKP1 | S-phase kinase-associated protein 1 | 0.0246672 |
| GYS1 | glycogen synthase 1 (muscle) | 0.024535 |
| FAM219A | family with sequence similarity 219, member A | 0.0243878 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0242959 |
| WDR37 | WD repeat domain 37 | 0.0239586 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0237414 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0236396 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0234242 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.023396 |
| SMYD3 | SET and MYND domain containing 3 | 0.0233544 |
| STARD3NL | STARD3 N-terminal like | 0.0232166 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0231231 |
| PLCB4 | phospholipase C, beta 4 | 0.023121 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0231005 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0230544 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0229748 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.022836 |
| APOL2 | apolipoprotein L, 2 | 0.0228265 |
| CADM1 | cell adhesion molecule 1 | 0.0225458 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 0.0224181 |
| CIRSR | corepressor of RBPJ and splicing regulator | 0.0223903 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0223735 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.0223675 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0223168 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0221736 |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B | 0.0219942 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0219141 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.021864 |
| TTK | TTK protein kinase | 0.0218448 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.021649 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0216272 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0215228 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0215173 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0213044 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase | 0.0213009 |
| CD2AP | CD2-associated protein | 0.0212929 |
| BBX | bobby sox homolog (Drosophila) | 0.0210346 |
| LEPROT | leptin receptor overlapping transcript | 0.021033 |
| CEP95 | centrosomal protein 95kDa | 0.0209981 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0208852 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0208434 |
| YTHDC1 | YTH domain containing 1 | 0.0207125 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0206315 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0205983 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0203603 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0202515 |
| INVS | inversin | 0.0202192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261819 |
| MT2A | metallothionein 2A | -0.238511 |
| VIM | vimentin | -0.212335 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.147064 |
| FN1 | fibronectin 1 | -0.126682 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.11421 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.103664 |
| POTEF | POTE ankyrin domain family, member F | -0.103621 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.101704 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0962593 |
| STC1 | stanniocalcin 1 | -0.0880936 |
| HLA-B | major histocompatibility complex, class I, B | -0.0836693 |
| TMSB10 | thymosin beta 10 | -0.0831475 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0776879 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0737106 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0728799 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0694061 |
| ENO1 | enolase 1, (alpha) | -0.0664948 |
| CD44 | CD44 molecule (Indian blood group) | -0.0647149 |
| ASPH | aspartate beta-hydroxylase | -0.0608365 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0593013 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0574289 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0573463 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0544598 |
| CDH13 | cadherin 13 | -0.0525669 |
| RTN4 | reticulon 4 | -0.0517487 |
| PKM | pyruvate kinase, muscle | -0.0490384 |
| HMGA2 | high mobility group AT-hook 2 | -0.0480073 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.047886 |
| FMNL2 | formin-like 2 | -0.0471901 |
| LDHA | lactate dehydrogenase A | -0.04719 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.046516 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0465012 |
| SEPTIN7 | septin 7 | -0.0461732 |
| ECE1 | endothelin converting enzyme 1 | -0.045912 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0444686 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0437633 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0431307 |
| NAV2 | neuron navigator 2 | -0.0428396 |
| IL6 | interleukin 6 | -0.042755 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0424302 |
| RNF24 | ring finger protein 24 | -0.0418206 |
| FOSL1 | FOS-like antigen 1 | -0.0416497 |
| UBC | ubiquitin C | -0.0416067 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.041439 |
| EGR1 | early growth response 1 | -0.0408755 |
| FTL | ferritin, light polypeptide | -0.0408213 |
| MAP1B | microtubule-associated protein 1B | -0.040805 |
| PTMA | prothymosin, alpha | -0.0404023 |
| USP34 | ubiquitin specific peptidase 34 | -0.0403849 |
| ERBIN | erbb2 interacting protein | -0.0396258 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0393387 |
| HDAC9 | histone deacetylase 9 | -0.0384445 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0381501 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0377722 |
| HLA-A | major histocompatibility complex, class I, A | -0.0365617 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0348626 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0344355 |
| S100A10 | S100 calcium binding protein A10 | -0.034249 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.034043 |
| TAGLN2 | transgelin 2 | -0.0334956 |
| HIP1 | huntingtin interacting protein 1 | -0.0332954 |
| TLN1 | talin 1 | -0.0331683 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0330732 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0329734 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0323121 |
| RND3 | Rho family GTPase 3 | -0.0322532 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0317055 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0310992 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0307241 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0303391 |
| RPL23 | ribosomal protein L23 | -0.030264 |
| PTK2 | protein tyrosine kinase 2 | -0.0299357 |
| RAI1 | retinoic acid induced 1 | -0.0297811 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0297506 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0296201 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0295975 |
| S100A6 | S100 calcium binding protein A6 | -0.0295922 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0295646 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0290773 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0290013 |
| CDK6 | cyclin-dependent kinase 6 | -0.0289546 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0289527 |
| RPS6 | ribosomal protein S6 | -0.0289243 |
| QKI | QKI, KH domain containing, RNA binding | -0.0287178 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0287123 |
| MYADM | myeloid-associated differentiation marker | -0.0284904 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0280827 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0275432 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0274832 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0274488 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0273831 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0271661 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0265141 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0264284 |
| VEGFA | vascular endothelial growth factor A | -0.0262883 |
| FAM107B | family with sequence similarity 107, member B | -0.0259422 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0259246 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0257952 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0257615 |
