| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WAC | WW domain containing adaptor with coiled-coil | 0.0879414 |
| FNDC3B | fibronectin type III domain containing 3B | 0.07051 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0656493 |
| RBM39 | RNA binding motif protein 39 | 0.064021 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0616672 |
| PTMA | prothymosin, alpha | 0.0609089 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0509916 |
| RNF145 | ring finger protein 145 | 0.0500593 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0482992 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0480315 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0476783 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0471427 |
| ACER3 | alkaline ceramidase 3 | 0.0457443 |
| CANX | calnexin | 0.0452081 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0445894 |
| SGO2 | shugoshin 2 | 0.0445491 |
| JMJD1C | jumonji domain containing 1C | 0.0442796 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0430993 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0426684 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0423777 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0421941 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0416935 |
| FNIP1 | folliculin interacting protein 1 | 0.0416521 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0409398 |
| PRELID2 | PRELI domain containing 2 | 0.0406315 |
| MT2A | metallothionein 2A | 0.0405926 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0398765 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0398124 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0395342 |
| TMSB10 | thymosin beta 10 | 0.0394888 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0389136 |
| SDC4 | syndecan 4 | 0.0382606 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0382368 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0381011 |
| FUS | FUS RNA binding protein | 0.0374429 |
| SETD5 | SET domain containing 5 | 0.0373457 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0370108 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0369432 |
| IER3 | immediate early response 3 | 0.036841 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0364889 |
| CLINT1 | clathrin interactor 1 | 0.0360514 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0354956 |
| ERBIN | erbb2 interacting protein | 0.0354194 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0351968 |
| CALR | calreticulin | 0.0346268 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0343158 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0341299 |
| EGFR | epidermal growth factor receptor | 0.034053 |
| SNX14 | sorting nexin 14 | 0.0338658 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0337793 |
| NUP58 | nucleoporin 58 | 0.0336443 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0336105 |
| ECT2 | epithelial cell transforming 2 | 0.0331932 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0329889 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0327044 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0326194 |
| RPL37A | ribosomal protein L37a | 0.0324526 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0322287 |
| METTL15 | methyltransferase like 15 | 0.0315294 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0314543 |
| CEP295 | centrosomal protein 295kDa | 0.0313026 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0312754 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0307234 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0305484 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0305432 |
| PAPOLA | poly(A) polymerase alpha | 0.0303402 |
| DEK | DEK proto-oncogene | 0.0302777 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0301408 |
| RPL35A | ribosomal protein L35a | 0.0300331 |
| PDS5A | PDS5 cohesin associated factor A | 0.0299016 |
| APP | amyloid beta (A4) precursor protein | 0.0297699 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0296525 |
| RPL32 | ribosomal protein L32 | 0.0295274 |
| KIF5B | kinesin family member 5B | 0.0293998 |
| SUCO | SUN domain containing ossification factor | 0.0292711 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0290924 |
| SRPK2 | SRSF protein kinase 2 | 0.0290218 |
| CFDP1 | craniofacial development protein 1 | 0.0289579 |
| TPX2 | TPX2, microtubule-associated | 0.0287273 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | 0.028651 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0285393 |
| HJURP | Holliday junction recognition protein | 0.0284726 |
| SPAG9 | sperm associated antigen 9 | 0.0284347 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.028403 |
| CENPE | centromere protein E, 312kDa | 0.0283552 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0283512 |
| OLA1 | Obg-like ATPase 1 | 0.0282598 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0281603 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0281264 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0279648 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0277889 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | 0.0277656 |
| CALU | calumenin | 0.0275334 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0273809 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0273225 |
| RBM25 | RNA binding motif protein 25 | 0.0269219 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0268757 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.026813 |
| PHF21A | PHD finger protein 21A | 0.026794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0267718 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167119 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0948315 |
| CD44 | CD44 molecule (Indian blood group) | -0.0716781 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0626462 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.055397 |
| PKM | pyruvate kinase, muscle | -0.0458238 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.040728 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0399688 |
| POTEF | POTE ankyrin domain family, member F | -0.0380781 |
| ENO1 | enolase 1, (alpha) | -0.0372425 |
| FLNA | filamin A, alpha | -0.0357265 |
| LDHA | lactate dehydrogenase A | -0.0356605 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0355063 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0351435 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0339556 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0334645 |
| ANO6 | anoctamin 6 | -0.0328449 |
| SMYD3 | SET and MYND domain containing 3 | -0.0326883 |
| SQSTM1 | sequestosome 1 | -0.0325698 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0323693 |
| CCND1 | cyclin D1 | -0.031668 |
| LAMA5 | laminin, alpha 5 | -0.031205 |
| CCDC91 | coiled-coil domain containing 91 | -0.0311668 |
| IGF2 | insulin-like growth factor 2 | -0.0311039 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0305135 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0303643 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0301099 |
| DENND5B | DENN/MADD domain containing 5B | -0.0300244 |
| KDM6B | lysine (K)-specific demethylase 6B | -0.0300168 |
| PER1 | period circadian clock 1 | -0.0296623 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0295361 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0287365 |
| ZFAND5 | zinc finger, AN1-type domain 5 | -0.0287131 |
| SVIL | supervillin | -0.0284842 |
| PPHLN1 | periphilin 1 | -0.0283961 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.028163 |
| SEPTIN2 | septin 2 | -0.0278281 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0276963 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0275907 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.0273655 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0272468 |
| CNKSR3 | CNKSR family member 3 | -0.0257701 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0257149 |
| MYO10 | myosin X | -0.0255432 |
| TAGLN2 | transgelin 2 | -0.0250251 |
| RTN4 | reticulon 4 | -0.0249803 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | -0.0249799 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0249532 |
| TNRC18 | trinucleotide repeat containing 18 | -0.0249068 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0248641 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0247752 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0246342 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0242083 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0240344 |
| ABR | active BCR-related | -0.0237914 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.023735 |
| KIF2A | kinesin heavy chain member 2A | -0.0235758 |
| RFX7 | regulatory factor X, 7 | -0.0234088 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.0230299 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0229504 |
| HMGA2 | high mobility group AT-hook 2 | -0.0227051 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0226332 |
| ITGAV | integrin, alpha V | -0.0224662 |
| CPNE1 | copine I | -0.0222746 |
| HMGA1 | high mobility group AT-hook 1 | -0.0222228 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0221298 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0217804 |
| ZNF254 | zinc finger protein 254 | -0.0217522 |
| ZRANB2 | zinc finger, RAN-binding domain containing 2 | -0.0215479 |
| LARP4 | La ribonucleoprotein domain family, member 4 | -0.021533 |
| PRKCA | protein kinase C, alpha | -0.0215287 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0215124 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0210427 |
| NCKAP1 | NCK-associated protein 1 | -0.0210369 |
| ZNF292 | zinc finger protein 292 | -0.0209702 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0208226 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0207515 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0205754 |
| CASP8AP2 | caspase 8 associated protein 2 | -0.0204627 |
| INTS6 | integrator complex subunit 6 | -0.0204365 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.020314 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0201944 |
| WWC2 | WW and C2 domain containing 2 | -0.0201262 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.0199832 |
| BRD4 | bromodomain containing 4 | -0.0199396 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0199185 |
| PODXL | podocalyxin-like | -0.0199018 |
| LIMA1 | LIM domain and actin binding 1 | -0.0197609 |
| CEP152 | centrosomal protein 152kDa | -0.019747 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0197334 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0197139 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0195939 |
| SKIL | SKI-like proto-oncogene | -0.019552 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0194985 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0193978 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0192548 |
| ADIPOR2 | adiponectin receptor 2 | -0.0191441 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.0191238 |
| FRMD6 | FERM domain containing 6 | -0.0190923 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.018945 |
