| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | olaparib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the olaparib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.264618 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.208919 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.188784 |
| PTMA | prothymosin, alpha | 0.10744 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0871113 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0838073 |
| B2M | beta-2-microglobulin | 0.0784562 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0777631 |
| RPS6 | ribosomal protein S6 | 0.0766506 |
| CENPF | centromere protein F, 350/400kDa | 0.0742969 |
| FTL | ferritin, light polypeptide | 0.0712572 |
| SMOX | spermine oxidase | 0.0665713 |
| OSMR | oncostatin M receptor | 0.0655469 |
| ITGA1 | integrin, alpha 1 | 0.0654002 |
| HLA-B | major histocompatibility complex, class I, B | 0.0632034 |
| AHR | aryl hydrocarbon receptor | 0.0599479 |
| RBM39 | RNA binding motif protein 39 | 0.0588652 |
| TMSB10 | thymosin beta 10 | 0.0583078 |
| TPR | translocated promoter region, nuclear basket protein | 0.0560352 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0542169 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0541304 |
| MKI67 | marker of proliferation Ki-67 | 0.0522213 |
| RNF145 | ring finger protein 145 | 0.0520695 |
| RUNX2 | runt-related transcription factor 2 | 0.0517892 |
| TXNIP | thioredoxin interacting protein | 0.0515895 |
| SFTPA2 | surfactant protein A2 | 0.0507706 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0503392 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0498173 |
| TMEM156 | transmembrane protein 156 | 0.0493126 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0486033 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.048535 |
| RPL35A | ribosomal protein L35a | 0.048464 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0476632 |
| MT2A | metallothionein 2A | 0.0467988 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0462818 |
| VEGFA | vascular endothelial growth factor A | 0.043537 |
| GLIS3 | GLIS family zinc finger 3 | 0.0434126 |
| OGA | O-GlcNAcase | 0.0430801 |
| GOLGA4 | golgin A4 | 0.0429155 |
| TMSB4X | thymosin beta 4, X-linked | 0.0421578 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.041291 |
| CD44 | CD44 molecule (Indian blood group) | 0.0406349 |
| ASPH | aspartate beta-hydroxylase | 0.039702 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391977 |
| ETV1 | ets variant 1 | 0.0381756 |
| DST | dystonin | 0.0369236 |
| PLIN2 | perilipin 2 | 0.0365473 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0365204 |
| PRELID2 | PRELI domain containing 2 | 0.0356747 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0356713 |
| S100A6 | S100 calcium binding protein A6 | 0.0352719 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0348753 |
| TXNRD1 | thioredoxin reductase 1 | 0.0343595 |
| RPL37A | ribosomal protein L37a | 0.0342075 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0341814 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0340009 |
| ETV6 | ets variant 6 | 0.0338282 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0338185 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0332974 |
| TPI1 | triosephosphate isomerase 1 | 0.0332644 |
| MIS18BP1 | MIS18 binding protein 1 | 0.032932 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0328695 |
| FN1 | fibronectin 1 | 0.0326741 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0326287 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.03246 |
| NRP1 | neuropilin 1 | 0.0323277 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0320198 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0319111 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.031575 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0315738 |
| FNBP1 | formin binding protein 1 | 0.0315331 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0311931 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0307525 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0307262 |
| RTN4 | reticulon 4 | 0.0304053 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0302764 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0302161 |
| CD109 | CD109 molecule | 0.0301487 |
| SQSTM1 | sequestosome 1 | 0.0300711 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.030035 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0298961 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0298519 |
| KIF5B | kinesin family member 5B | 0.0295732 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0293301 |
| AOPEP | aminopeptidase O (putative) | 0.029269 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0290636 |
| HMGB3 | high mobility group box 3 | 0.0288674 |
| ZFR | zinc finger RNA binding protein | 0.0287933 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.028627 |
| HLA-A | major histocompatibility complex, class I, A | 0.028547 |
| CLTC | clathrin, heavy chain (Hc) | 0.0282815 |
| ADD3 | adducin 3 (gamma) | 0.0280752 |
| CAB39 | calcium binding protein 39 | 0.0280674 |
| ZNF292 | zinc finger protein 292 | 0.0279537 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0278187 |
| RPL37 | ribosomal protein L37 | 0.0277288 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0276538 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0276157 |
| PELO | pelota homolog (Drosophila) | 0.0270803 |
| TMEM165 | transmembrane protein 165 | 0.0269998 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0891743 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0767323 |
| INTS6 | integrator complex subunit 6 | -0.067813 |
| HMGA2 | high mobility group AT-hook 2 | -0.0644653 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0632881 |
| FLNA | filamin A, alpha | -0.0608624 |
| UBC | ubiquitin C | -0.0576295 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0530349 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0507216 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0489672 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0473465 |
| SMAD3 | SMAD family member 3 | -0.0433131 |
| NRG1 | neuregulin 1 | -0.0407414 |
| AEBP2 | AE binding protein 2 | -0.0391419 |
| EGFR | epidermal growth factor receptor | -0.0368073 |
| LOXL2 | lysyl oxidase-like 2 | -0.0359564 |
| TUFT1 | tuftelin 1 | -0.0348407 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0344552 |
| PALLD | palladin, cytoskeletal associated protein | -0.0344178 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0341485 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.034095 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0338399 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0324371 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0306158 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0303335 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0303072 |
| RASAL2 | RAS protein activator like 2 | -0.0301451 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0294998 |
| CTBP2 | C-terminal binding protein 2 | -0.0287365 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0278655 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0277743 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0269425 |
| POTEF | POTE ankyrin domain family, member F | -0.0268131 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0266757 |
| LRRC23 | leucine rich repeat containing 23 | -0.0254815 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0251883 |
| RPS27A | ribosomal protein S27a | -0.0250886 |
| AHNAK | AHNAK nucleoprotein | -0.0250727 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0248312 |
| FLNB | filamin B, beta | -0.0243236 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0242979 |
| ABR | active BCR-related | -0.0242273 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0241261 |
| PLEC | plectin | -0.0238734 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.02355 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0235341 |
| POU2F2 | POU class 2 homeobox 2 | -0.0233847 |
| RUNX1 | runt-related transcription factor 1 | -0.0230333 |
| FGF18 | fibroblast growth factor 18 | -0.0223922 |
| STC2 | stanniocalcin 2 | -0.0223269 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0215938 |
| MYOF | myoferlin | -0.0212904 |
| NABP1 | nucleic acid binding protein 1 | -0.0209551 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0208609 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0208123 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0196202 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.019175 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.019064 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0189895 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0189417 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0183564 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.018315 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0182113 |
| IVNS1ABP | influenza virus NS1A binding protein | -0.0179605 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0176351 |
| NDRG1 | N-myc downstream regulated 1 | -0.0175876 |
| LOX | lysyl oxidase | -0.0174661 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0174344 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0173927 |
| SVIL | supervillin | -0.0173323 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0171452 |
| NEBL | nebulette | -0.0170658 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0170127 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0170036 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0169705 |
| BAIAP2 | BAI1-associated protein 2 | -0.0166671 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | -0.0165457 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0165323 |
| UBAP2 | ubiquitin associated protein 2 | -0.0164774 |
| MEF2D | myocyte enhancer factor 2D | -0.0163625 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0159999 |
| ATF6 | activating transcription factor 6 | -0.0158929 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0158373 |
| TGFB1 | transforming growth factor, beta 1 | -0.0158273 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.015771 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0157692 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0157341 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0156813 |
| SEPTIN9 | septin 9 | -0.0154947 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0154939 |
| VCL | vinculin | -0.0154616 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0154408 |
| ATN1 | atrophin 1 | -0.0153199 |
| CCDC138 | coiled-coil domain containing 138 | -0.0153008 |
| ACTN1 | actinin, alpha 1 | -0.0152993 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0150117 |
| PER1 | period circadian clock 1 | -0.0149399 |
| FOSL1 | FOS-like antigen 1 | -0.0149375 |
| NAV1 | neuron navigator 1 | -0.0149282 |
| PRKCA | protein kinase C, alpha | -0.0148821 |
