oleandomycin-2018 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the oleandomycin-2018 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
ACAN aggrecan
ACBD4 acyl-CoA binding domain containing 4
ADARB1 adenosine deaminase, RNA-specific, B1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATN1 atrophin 1
ATXN7 ataxin 7
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BANP BTG3 associated nuclear protein
C16ORF58 chromosome 16 open reading frame 58
C1QTNF1 C1q and tumor necrosis factor related protein 1
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNJ cyclin J
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDHR2 cadherin-related family member 2
CEL carboxyl ester lipase
CER1 cerberus 1, DAN family BMP antagonist
CLTCL1 clathrin, heavy chain-like 1
CYB561 cytochrome b561
DAPK1 death-associated protein kinase 1
DBP D site of albumin promoter (albumin D-box) binding protein
DBT dihydrolipoamide branched chain transacylase E2
DEF6 differentially expressed in FDCP 6 homolog (mouse)
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
FAM102A family with sequence similarity 102, member A
FBXO3 F-box protein 3
FCHO1 FCH domain only 1
FES FES proto-oncogene, tyrosine kinase
GALK1 galactokinase 1
GINS3 GINS complex subunit 3 (Psf3 homolog)
GOLGA2 golgin A2
HCRP1 hepatocellular carcinoma-related HCRP1
HEMK1 HemK methyltransferase family member 1
HIST1H4J histone cluster 1, H4j
HIST3H3 histone cluster 3, H3
IDS iduronate 2-sulfatase
IFITM3 interferon induced transmembrane protein 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGHM immunoglobulin heavy constant mu
INTS1 integrator complex subunit 1
INTS7 integrator complex subunit 7
JRK Jrk homolog (mouse)
KRI1 KRI1 homolog (S. cerevisiae)
LHB luteinizing hormone beta polypeptide
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LTB4R leukotriene B4 receptor
LUZP1 leucine zipper protein 1
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAP7D3 MAP7 domain containing 3
MED6 mediator complex subunit 6
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTMR2 myotubularin related protein 2
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit
NCOA3 nuclear receptor coactivator 3
NEUROD4 neuronal differentiation 4
NFX1 nuclear transcription factor, X-box binding 1
NLRP3 NLR family, pyrin domain containing 3
NOTCH3 notch 3
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PLEC plectin
PRKCA protein kinase C, alpha
PROL1 proline rich, lacrimal 1
PRR15L proline rich 15-like
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
QTRT1 queuine tRNA-ribosyltransferase 1
REC8 REC8 meiotic recombination protein
RNF31 ring finger protein 31
SECISBP2L SECIS binding protein 2-like
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC35E3 solute carrier family 35, member E3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRPK2 SRSF protein kinase 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBC1D13 TBC1 domain family, member 13
TGM5 transglutaminase 5
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TK2 thymidine kinase 2, mitochondrial
TMEM161A transmembrane protein 161A
TMEM5 transmembrane protein 5
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TTC3 tetratricopeptide repeat domain 3
TTLL4 tubulin tyrosine ligase-like family member 4
TULP3 tubby like protein 3
UEVLD UEV and lactate/malate dehyrogenase domains
WDR61 WD repeat domain 61
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBTB44 zinc finger and BTB domain containing 44
ZNF318 zinc finger protein 318

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACIN1 apoptotic chromatin condensation inducer 1
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
AES amino-terminal enhancer of split
ARG1 arginase 1
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ASCC1 activating signal cointegrator 1 complex subunit 1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
C10ORF88 chromosome 10 open reading frame 88
CCNC cyclin C
CDC50A cell division cycle 50 P4-ATPase accessory subunit A
CLDND1 claudin domain containing 1
CLEC7A C-type lectin domain family 7, member A
CLK1 CDC-like kinase 1
CNR2 cannabinoid receptor 2 (macrophage)
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CYB5R3 cytochrome b5 reductase 3
DCAF16 DDB1 and CUL4 associated factor 16
DCAF6 DDB1 and CUL4 associated factor 6
DCTN6 dynactin 6
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DNAAF2 dynein, axonemal, assembly factor 2
DPF3 D4, zinc and double PHD fingers, family 3
DROSHA drosha, ribonuclease type III
EAPP E2F-associated phosphoprotein
EDAR ectodysplasin A receptor
EVL Enah/Vasp-like
FANCF Fanconi anemia, complementation group F
FBXO5 F-box protein 5
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GAB2 GRB2-associated binding protein 2
GATAD2A GATA zinc finger domain containing 2A
GIMAP6 GTPase, IMAP family member 6
GPN3 GPN-loop GTPase 3
GPR27 G protein-coupled receptor 27
HACD2 3-hydroxyacyl-CoA dehydratase 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB3P1 high mobility group box 3 pseudogene 1
HP haptoglobin
IGSF6 immunoglobulin superfamily, member 6
JADE1 jade family PHD finger 1
KIAA0232 KIAA0232
KLF7 Kruppel-like factor 7 (ubiquitous)
LAS1L LAS1-like (S. cerevisiae)
LIG1 ligase I, DNA, ATP-dependent
LIN7A lin-7 homolog A (C. elegans)
MAGT1 magnesium transporter 1
MEST mesoderm specific transcript
MMP2 matrix metallopeptidase 2
MRPL33 mitochondrial ribosomal protein L33
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MXRA8 matrix-remodelling associated 8
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NEK7 NIMA-related kinase 7
NSUN3 NOP2/Sun domain family, member 3
NUCLEOLIN nucleolin multifunctional protein
PCNA proliferating cell nuclear antigen
PEX12 peroxisomal biogenesis factor 12
PIGK phosphatidylinositol glycan anchor biosynthesis, class K
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PROSER1 proline and serine rich 1
RAD51AP1 RAD51 associated protein 1
RAD54L RAD54-like (S. cerevisiae)
RARS arginyl-tRNA synthetase
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RINT1 RAD50 interactor 1
RNF122 ring finger protein 122
RPL36A ribosomal protein L36a
RPS17P5 ribosomal protein S17 pseudogene 5
SECISBP2 SECIS binding protein 2
SEH1L SEH1-like (S. cerevisiae)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SPX spexin hormone
SREBF1 sterol regulatory element binding transcription factor 1
STXBP3 syntaxin binding protein 3
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMEM127 transmembrane protein 127
TMEM14A transmembrane protein 14A
TMEM184B transmembrane protein 184B
TRHDE thyrotropin-releasing hormone degrading enzyme
TRIM26 tripartite motif containing 26
TRIM8 tripartite motif containing 8
UNKL unkempt family zinc finger-like
USP6 ubiquitin specific peptidase 6
WDR3 WD repeat domain 3
WDR82 WD repeat domain 82
ZC3H3 zinc finger CCCH-type containing 3
ZNF140 zinc finger protein 140
ZNF32 zinc finger protein 32
ZNF8 zinc finger protein 8