olig2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description oligodendrocyte lineage transcription factor 2|This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10215)
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Genes

13 genes co-occuring with the biological term olig2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
H3F3A H3 histone, family 3A
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL13RA2 interleukin 13 receptor, alpha 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMO1 LIM domain only 1 (rhombotin 1)
MAG myelin associated glycoprotein
MIR17 microRNA 17
NOTCH1 notch 1
OLIG1 oligodendrocyte transcription factor 1
OLIG2 oligodendrocyte lineage transcription factor 2
RHOA ras homolog family member A
SHH sonic hedgehog
TP53 tumor protein p53