oligoastrocytoma Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655)|A WHO grade II tumor composed of a conspicuous mixture of two distinct neoplastic cell types morphologically resembling the tumor cells in oligodendroglioma and diffuse astrocytoma. (WHO) (Experimental Factor Ontology, EFO_0000630)
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Genes

7 genes co-occuring with the biological term oligoastrocytoma in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
EGFR epidermal growth factor receptor
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
MIB1 mindbomb E3 ubiquitin protein ligase 1
PTEN phosphatase and tensin homolog
TP53 tumor protein p53