omeprazole-2467 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the omeprazole-2467 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALB albumin
ANK2 ankyrin 2, neuronal
AQP9 aquaporin 9
ARHGAP1 Rho GTPase activating protein 1
BCL9 B-cell CLL/lymphoma 9
BIN1 bridging integrator 1
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
C4BPB complement component 4 binding protein, beta
CD22 CD22 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDRT1 CMT1A duplicated region transcript 1
CFAP45 cilia and flagella associated protein 45
CLMN calmin (calponin-like, transmembrane)
CNGB3 cyclic nucleotide gated channel beta 3
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DNASE2B deoxyribonuclease II beta
DOC2B double C2-like domains, beta
DRD5 dopamine receptor D5
DRICH1 aspartate-rich 1
EFNA5 ephrin-A5
EPN2 epsin 2
ESR1 estrogen receptor 1
FBXO4 F-box protein 4
FCAR Fc fragment of IgA receptor
FLJ11292
FOXG1 forkhead box G1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNG12 guanine nucleotide binding protein (G protein), gamma 12
H2AFX H2A histone family, member X
HIST1H3G histone cluster 1, H3g
HIST1H3I histone cluster 1, H3i
IDS iduronate 2-sulfatase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL2 interleukin 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRTAP2-4 keratin associated protein 2-4
LMOD1 leiomodin 1 (smooth muscle)
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAGOH2P mago-nashi homolog 2, pseudogene
MAML3 mastermind-like 3 (Drosophila)
MRPS12 mitochondrial ribosomal protein S12
MTSS1L metastasis suppressor 1-like
MYO1E myosin IE
NAG18 NAG18 mRNA
NEUROD4 neuronal differentiation 4
NF2 neurofibromin 2 (merlin)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOV nephroblastoma overexpressed
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PDE4D phosphodiesterase 4D, cAMP-specific
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PGAM2 phosphoglycerate mutase 2 (muscle)
PGLYRP4 peptidoglycan recognition protein 4
PLA2G3 phospholipase A2, group III
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PLXNC1 plexin C1
PNPLA3 patatin-like phospholipase domain containing 3
PTCRA pre T-cell antigen receptor alpha
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RANBP1 RAN binding protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBPMS RNA binding protein with multiple splicing
RRBP1 ribosome binding protein 1
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLAMF7 SLAM family member 7
SLAMF8 SLAM family member 8
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A6 solute carrier family 16, member 6
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNX13 sorting nexin 13
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STMN4 stathmin-like 4
SYT5 synaptotagmin V
TCF3 transcription factor 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMEM212 transmembrane protein 212
TNK1 tyrosine kinase, non-receptor, 1
TRIM49 tripartite motif containing 49
TTC38 tetratricopeptide repeat domain 38
TUBB2A tubulin, beta 2A class IIa
TUBG2 tubulin, gamma 2
TXNRD2 thioredoxin reductase 2
UBE3A ubiquitin protein ligase E3A
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF471 zinc finger protein 471
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACO1 aconitase 1, soluble
AHR aryl hydrocarbon receptor
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASB7 ankyrin repeat and SOCS box containing 7
BPHL biphenyl hydrolase-like (serine hydrolase)
C17ORF53 chromosome 17 open reading frame 53
C21ORF91 chromosome 21 open reading frame 91
C5ORF28 chromosome 5 open reading frame 28
C5ORF30 chromosome 5 open reading frame 30
CAPN1 calpain 1, (mu/I) large subunit
CARF calcium responsive transcription factor
CCDC106 coiled-coil domain containing 106
CCDC6 coiled-coil domain containing 6
CLCN2 chloride channel, voltage-sensitive 2
CLEC2D C-type lectin domain family 2, member D
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
DBR1 debranching RNA lariats 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNM3 dynamin 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
EGR2 early growth response 2
ELMO3 engulfment and cell motility 3
EML4 echinoderm microtubule associated protein like 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM160B2 family with sequence similarity 160, member B2
FAM50B family with sequence similarity 50, member B
FKBPL FK506 binding protein like
G6PD glucose-6-phosphate dehydrogenase
GALE UDP-galactose-4-epimerase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK3P glycerol kinase 3 pseudogene
GNG7 guanine nucleotide binding protein (G protein), gamma 7
HRH2 histamine receptor H2
ICAM5 intercellular adhesion molecule 5, telencephalin
INF2 inverted formin, FH2 and WH2 domain containing
IRS1 insulin receptor substrate 1
KLHL21 kelch-like family member 21
LIMD2 LIM domain containing 2
LMAN1 lectin, mannose-binding, 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MANSC1 MANSC domain containing 1
MDM4 MDM4, p53 regulator
MED9 mediator complex subunit 9
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOCS3 molybdenum cofactor synthesis 3
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCKAP1L NCK-associated protein 1-like
NLK nemo-like kinase
NR1H3 nuclear receptor subfamily 1, group H, member 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCBP4 poly(rC) binding protein 4
PLCD1 phospholipase C, delta 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PRKCZ protein kinase C, zeta
PRSS53 protease, serine, 53
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB33A RAB33A, member RAS oncogene family
RGS13 regulator of G-protein signaling 13
SCAMP5 secretory carrier membrane protein 5
SENP7 SUMO1/sentrin specific peptidase 7
SETD1A SET domain containing 1A
SHPK sedoheptulokinase
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNX16 sorting nexin 16
STK16 serine/threonine kinase 16
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TEP1 telomerase-associated protein 1
TERT telomerase reverse transcriptase
TIAM2 T-cell lymphoma invasion and metastasis 2
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM36 tripartite motif containing 36
UNC119 unc-119 homolog (C. elegans)
ZBTB22 zinc finger and BTB domain containing 22
ZBTB39 zinc finger and BTB domain containing 39
ZBTB6 zinc finger and BTB domain containing 6
ZFAND3 zinc finger, AN1-type domain 3
ZNF134 zinc finger protein 134
ZNF345 zinc finger protein 345
ZNF37BP zinc finger protein 37B, pseudogene
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF528 zinc finger protein 528
ZNF74 zinc finger protein 74