omeprazole-6606 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the omeprazole-6606 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADRB3 adrenoceptor beta 3
AFF1 AF4/FMR2 family, member 1
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BLVRA biliverdin reductase A
C14ORF1 chromosome 14 open reading frame 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CADM3 cell adhesion molecule 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CD1C CD1c molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CLCN6 chloride channel, voltage-sensitive 6
CLEC4E C-type lectin domain family 4, member E
CLIC2 chloride intracellular channel 2
CRHR1 corticotropin releasing hormone receptor 1
CRHR2 corticotropin releasing hormone receptor 2
CRYGC crystallin, gamma C
CSHL1 chorionic somatomammotropin hormone-like 1
CTSE cathepsin E
CWH43 cell wall biogenesis 43 C-terminal homolog (S. cerevisiae)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGCR6L DiGeorge syndrome critical region gene 6-like
DUSP10 dual specificity phosphatase 10
EDNRA endothelin receptor type A
EFHC2 EF-hand domain (C-terminal) containing 2
ELN elastin
EMID1 EMI domain containing 1
FABP3 fatty acid binding protein 3, muscle and heart
FAM107A family with sequence similarity 107, member A
FBLN1 fibulin 1
FBXO21 F-box protein 21
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GZMK granzyme K (granzyme 3; tryptase II)
HEXA hexosaminidase A (alpha polypeptide)
HIST1H3I histone cluster 1, H3i
HOXD9 homeobox D9
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IDS iduronate 2-sulfatase
IFNA8 interferon, alpha 8
IGHD immunoglobulin heavy constant delta
IL1R1 interleukin 1 receptor, type I
ING2 inhibitor of growth family, member 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JPH3 junctophilin 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF13A kinesin family member 13A
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLK7 kallikrein-related peptidase 7
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC48 leucine rich repeat containing 48
LY9 lymphocyte antigen 9
MAGEB2 melanoma antigen family B2
MCF2L MCF.2 cell line derived transforming sequence-like
MED25 mediator complex subunit 25
MEP1B meprin A, beta
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MMP11 matrix metallopeptidase 11
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NPR1 natriuretic peptide receptor 1
OAZ3 ornithine decarboxylase antizyme 3
PACRG PARK2 co-regulated
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCH1 phospholipase C, eta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRELP proline/arginine-rich end leucine-rich repeat protein
RASAL2 RAS protein activator like 2
RBMS2 RNA binding motif, single stranded interacting protein 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCGB1D1 secretoglobin, family 1D, member 1
SCN1B sodium channel, voltage gated, type I beta subunit
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLA Src-like-adaptor
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMC1A structural maintenance of chromosomes 1A
SMR3A submaxillary gland androgen regulated protein 3A
SPI1 Spi-1 proto-oncogene
SPRED2 sprouty-related, EVH1 domain containing 2
SRPX2 sushi-repeat containing protein, X-linked 2
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TEX13A testis expressed 13A
THRA thyroid hormone receptor, alpha
TRIM22 tripartite motif containing 22
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTLL3 tubulin tyrosine ligase-like family member 3
ZC3H7B zinc finger CCCH-type containing 7B

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARRB2 arrestin, beta 2
ATP10D ATPase, class V, type 10D
AXIN1 axin 1
BCL9 B-cell CLL/lymphoma 9
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF30 chromosome 11 open reading frame 30
C22ORF29 chromosome 22 open reading frame 29
C5ORF42 chromosome 5 open reading frame 42
C9ORF91 chromosome 9 open reading frame 91
CLDN1 claudin 1
CLDN4 claudin 4
CNN2 calponin 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CUZD1 CUB and zona pellucida-like domains 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DEAF1 DEAF1 transcription factor
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRAMD1C GRAM domain containing 1C
GRWD1 glutamate-rich WD repeat containing 1
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HLX H2.0-like homeobox
IFT54 intraflagellar transport 54
IL7R interleukin 7 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IPO8 importin 8
KDM4D lysine (K)-specific demethylase 4D
KIAA0753 KIAA0753
KIRREL kin of IRRE like (Drosophila)
LIN7B lin-7 homolog B (C. elegans)
LMCD1 LIM and cysteine-rich domains 1
LOC100127972 uncharacterized LOC100127972
LRRC8E leucine rich repeat containing 8 family, member E
MANBA mannosidase, beta A, lysosomal
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MDM4 MDM4, p53 regulator
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED18 mediator complex subunit 18
MFSD12 major facilitator superfamily domain containing 12
MFSD6 major facilitator superfamily domain containing 6
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTG1 mitochondrial ribosome-associated GTPase 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYLIP myosin regulatory light chain interacting protein
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NINL ninein-like
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLL polymerase (DNA directed), lambda
PORCN porcupine homolog (Drosophila)
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRR3 proline rich 3
PTK7 protein tyrosine kinase 7 (inactive)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RECQL4 RecQ protein-like 4
RPH3AL rabphilin 3A-like (without C2 domains)
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SKI SKI proto-oncogene
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNORA21 small nucleolar RNA, H/ACA box 21
SPAG7 sperm associated antigen 7
SPATA2L spermatogenesis associated 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM132A transmembrane protein 132A
TOM1 target of myb1 (chicken)
TOR4A torsin family 4, member A
TXLNG taxilin gamma
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
YOD1 YOD1 deubiquitinase
ZFP30 ZFP30 zinc finger protein
ZNF692 zinc finger protein 692
ZSCAN31 zinc finger and SCAN domain containing 31