| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ondansetron-3575 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| APC | adenomatous polyposis coli |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BIN1 | bridging integrator 1 |
| BTG2 | BTG family, member 2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD52 | CD52 molecule |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLDN8 | claudin 8 |
| COL1A1 | collagen, type I, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| DAO | D-amino-acid oxidase |
| DRD2 | dopamine receptor D2 |
| EFNA3 | ephrin-A3 |
| ELAC2 | elaC ribonuclease Z 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FABP6 | fatty acid binding protein 6, ileal |
| FLJ11292 | |
| FLT3 | fms-related tyrosine kinase 3 |
| FRMD1 | FERM domain containing 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPR27 | G protein-coupled receptor 27 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HMG20B | high mobility group 20B |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| ICOSLG | inducible T-cell co-stimulator ligand |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KIAA0391 | KIAA0391 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRC75B | leucine rich repeat containing 75B |
| LYST | lysosomal trafficking regulator |
| MAPK14 | mitogen-activated protein kinase 14 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP25 | matrix metallopeptidase 25 |
| MYOZ1 | myozenin 1 |
| NOTCH3 | notch 3 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPR3 | natriuretic peptide receptor 3 |
| NUP88 | nucleoporin 88kDa |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIP | prolactin-induced protein |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLAC4 | placenta-specific 4 |
| PLD3 | phospholipase D family, member 3 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POLM | polymerase (DNA directed), mu |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PQLC2 | PQ loop repeat containing 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PVALB | parvalbumin |
| RAB35 | RAB35, member RAS oncogene family |
| RBM26 | RNA binding motif protein 26 |
| RNF19B | ring finger protein 19B |
| RTEL1 | regulator of telomere elongation helicase 1 |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SMAD1 | SMAD family member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNX13 | sorting nexin 13 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STXBP5L | syntaxin binding protein 5-like |
| SYN2 | synapsin II |
| SYNJ2 | synaptojanin 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TBXA2R | thromboxane A2 receptor |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TOX4 | TOX high mobility group box family member 4 |
| TRIM29 | tripartite motif containing 29 |
| UBQLN4 | ubiquilin 4 |
| UBTD1 | ubiquitin domain containing 1 |
| UBXN1 | UBX domain protein 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF446 | zinc finger protein 446 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| ACTL8 | actin-like 8 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP13A2 | ATPase type 13A2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CRLF1 | cytokine receptor-like factor 1 |
| CUEDC1 | CUE domain containing 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM198B | family with sequence similarity 198, member B |
| FAM204A | family with sequence similarity 204, member A |
| FOXN2 | forkhead box N2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GPATCH2L | G patch domain containing 2-like |
| GPR176 | G protein-coupled receptor 176 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC8 | homeobox C8 |
| ICK | intestinal cell (MAK-like) kinase |
| IMPACT | impact RWD domain protein |
| IPO8 | importin 8 |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1107 | KIAA1107 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHX1 | LIM homeobox 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED15 | mediator complex subunit 15 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHB8 | protocadherin beta 8 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLXNA3 | plexin A3 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PRSS22 | protease, serine, 22 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TAGLN | transgelin |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOM1 | target of myb1 (chicken) |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM66 | tripartite motif containing 66 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF253 | zinc finger protein 253 |
| ZNF480 | zinc finger protein 480 |
| ZNF606 | zinc finger protein 606 |
| ZNF623 | zinc finger protein 623 |
| ZNF768 | zinc finger protein 768 |
| ZNF804A | zinc finger protein 804A |
