| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the ondansetron-6270 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGFG2 | ArfGAP with FG repeats 2 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALPK1 | alpha-kinase 1 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ARF6 | ADP-ribosylation factor 6 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAIAP2 | BAI1-associated protein 2 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BIN1 | bridging integrator 1 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CHMP7 | charged multivesicular body protein 7 |
| COL7A1 | collagen, type VII, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CUL4B | cullin 4B |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DCN | decorin |
| DIXDC1 | DIX domain containing 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK4 | dedicator of cytokinesis 4 |
| EFHD1 | EF-hand domain family, member D1 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ESRRA | estrogen-related receptor alpha |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM134B | family with sequence similarity 134, member B |
| FAM214B | family with sequence similarity 214, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLRX3 | glutaredoxin 3 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HFE | hemochromatosis |
| HNMT | histamine N-methyltransferase |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HOXC5 | homeobox C5 |
| HPS4 | Hermansky-Pudlak syndrome 4 |
| INO80D | INO80 complex subunit D |
| IRF4 | interferon regulatory factor 4 |
| ITGB6 | integrin, beta 6 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KDM6A | lysine (K)-specific demethylase 6A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLF6 | Kruppel-like factor 6 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIMK2 | LIM domain kinase 2 |
| LPIN2 | lipin 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MTMR7 | myotubularin related protein 7 |
| MYOF | myoferlin |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NRG2 | neuregulin 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| PALM | paralemmin |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLAUR | plasminogen activator, urokinase receptor |
| POU2F2 | POU class 2 homeobox 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SETD1A | SET domain containing 1A |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRCAP | Snf2-related CREBBP activator protein |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STRN | striatin, calmodulin binding protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TAOK2 | TAO kinase 2 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM259 | transmembrane protein 259 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBOX5 | U-box domain containing 5 |
| UBXN1 | UBX domain protein 1 |
| VAX2 | ventral anterior homeobox 2 |
| XDH | xanthine dehydrogenase |
| ZNF292 | zinc finger protein 292 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACTL8 | actin-like 8 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BEX4 | brain expressed, X-linked 4 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CAPN15 | calpain 15 |
| CCDC25 | coiled-coil domain containing 25 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CENPJ | centromere protein J |
| CLDN15 | claudin 15 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CXORF56 | chromosome X open reading frame 56 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERO1L | ERO1-like (S. cerevisiae) |
| EVPL | envoplakin |
| F8 | coagulation factor VIII, procoagulant component |
| FANCC | Fanconi anemia, complementation group C |
| FBRS | fibrosin |
| FCHSD2 | FCH and double SH3 domains 2 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLCN | folliculin |
| FMO4 | flavin containing monooxygenase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GID4 | GID complex subunit 4 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLCE | glucuronic acid epimerase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HIST1H2BF | histone cluster 1, H2bf |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| IFT22 | intraflagellar transport 22 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| KLHL21 | kelch-like family member 21 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC20 | leucine rich repeat containing 20 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAP9 | microtubule-associated protein 9 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICALL2 | MICAL-like 2 |
| MT1H | metallothionein 1H |
| MTRF1 | mitochondrial translational release factor 1 |
| MYO1D | myosin ID |
| NDFIP1 | Nedd4 family interacting protein 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PGBD5 | piggyBac transposable element derived 5 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PYGB | phosphorylase, glycogen; brain |
| RANBP17 | RAN binding protein 17 |
| RASA2 | RAS p21 protein activator 2 |
| RCOR3 | REST corepressor 3 |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RNF39 | ring finger protein 39 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAGLN | transgelin |
| TBC1D10B | TBC1 domain family, member 10B |
| TLN1 | talin 1 |
| TMEM2 | transmembrane protein 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| UBXN6 | UBX domain protein 6 |
| YBX2 | Y box binding protein 2 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF141 | zinc finger protein 141 |
| ZNF205 | zinc finger protein 205 |
| ZNF219 | zinc finger protein 219 |
| ZNF442 | zinc finger protein 442 |
| ZNF480 | zinc finger protein 480 |
| ZNF586 | zinc finger protein 586 |
| ZNF813 | zinc finger protein 813 |
